Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brianna M, Rivera"'
Autor:
Noah R. Johnson, Peng Yuan, Erika Castillo, T. Peter Lopez, Weizhou Yue, Annalise Bond, Brianna M. Rivera, Miranda C. Sullivan, Masakazu Hirouchi, Kurt Giles, Atsushi Aoyagi, Carlo Condello
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Tau-mediated neurodegeneration is driven by disease-activated microglia and suppressed by their pharmacological blockade. The authors identified drug dose- and sex-dependent residual microglial phenotypes, neuronal excitotoxicity, and animal survival
Externí odkaz:
https://doaj.org/article/b48523c2ca3f4e85a7a80f256c64823a
Autor:
Alison M. Maxwell, Peng Yuan, Brianna M. Rivera, Wilder Schaaf, Mihovil Mladinov, Vee P. Prasher, Andrew C. Robinson, William F. DeGrado, Carlo Condello
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Amyloid beta (Aβ) is thought to play a critical role in the pathogenesis of Alzheimer’s disease (AD). Prion-like Aβ polymorphs, or “strains”, can have varying pathogenicity and may underlie the phenotypic heterogeneity of the disease
Externí odkaz:
https://doaj.org/article/dce996dec328498197f03187eecb924c
Autor:
Carlo Condello, Jacob I. Ayers, Clifton L. Dalgard, M. Madhy Garcia Garcia, Brianna M. Rivera, William W. Seeley, Daniel P. Perl, Stanley B. Prusiner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 13
The amyotrophic lateral sclerosis–parkinsonism dementia complex (ALS-PDC) of Guam is an endemic neurodegenerative disease that features widespread tau tangles, occasional α-synuclein Lewy bodies, and sparse β-amyloid (Aβ) plaques distributed in
Autor:
Leah C, Dorman, Phi T, Nguyen, Caroline C, Escoubas, Ilia D, Vainchtein, Yinghong, Xiao, Peter V, Lidsky, Haruna, Nakajo, Nicholas J, Silva, Christian, Lagares-Linares, Ellen Y, Wang, Sunrae E, Taloma, Beatriz, Cuevas, Hiromi, Nakao-Inoue, Brianna M, Rivera, Bjoern, Schwer, Carlo, Condello, Raul, Andino, Tomasz J, Nowakowski, Anna V, Molofsky
Publikováno v:
bioRxiv : the preprint server for biology.
Microglia, the innate immune cells of the brain, are exquisitely sensitive to dynamic changes in the neural environment. Using single cell RNA sequencing of the postnatal somatosensory cortex during topographic remapping, we identified a type I inter
Autor:
Mihovil Mladinov, Alison M. Maxwell, Carlo Condello, Brianna M. Rivera, Vee P. Prasher, Wilder Schaaf, William F. DeGrado, Peng Yuan, Andrew C Robinson
0.ABSTRACTAmyloid beta (Aβ) is thought to play a critical role in the pathogenesis of Alzheimer’s disease (AD). Prion-like Aβ polymorphs, or “strains”, can have varying pathogenicity and may underlie the phenotypic heterogeneity of the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3209fa300548cb577d150fb2b729a8fd
https://doi.org/10.1101/2021.07.30.454527
https://doi.org/10.1101/2021.07.30.454527
Autor:
Noah R. Johnson, Brianna M. Rivera, Lopez Tp, Atsushi Aoyagi, Hirouchi M, Bond A, Yue W, Yuan P, Carlo Condello, Kurt Giles
Microglia are a fundamental component of pathogenesis in many neurological conditions and have specialized functions that vary by disease stage or specific pathology. Drugs targeting colony-stimulating factor-1 receptor (CSF1R) to block microglial pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc45eb63433603aeffff89bb009c9cc5
https://doi.org/10.1101/2021.03.20.436288
https://doi.org/10.1101/2021.03.20.436288
Autor:
Glenda M. Halliday, Carlo Condello, Sjoerd G. van Duinen, Lars Lannfelt, Stanley B. Prusiner, Joanne C. Lee, Weizhou Yue, C. Dirk Keene, Amanda L. Woerman, Brianna M. Rivera, Martin Ingelsson, William F. DeGrado, Atsushi Aoyagi, Jan Stöhr, Caroline Graff, Thomas D. Bird, William W. Seeley
Publikováno v:
Sci Transl Med
Science Translational Medicine, 11(490). AMER ASSOC ADVANCEMENT SCIENCE
Science Translational Medicine, 11(490). AMER ASSOC ADVANCEMENT SCIENCE
The hallmarks of Alzheimer's disease (AD) are the accumulation of A beta plaques and neurofibrillary tangles composed of hyperphosphorylated tau. We developed sensitive cellular assays using human embryonic kidney-293T cells to quantify intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525e4ae40e33592fd831ddb18fadabae
https://hdl.handle.net/1887/121879
https://hdl.handle.net/1887/121879
Autor:
Craig H. Kerr, Kathy H. Li, John D. Gross, Peter V. Lidsky, Arabinda Nayak, Brianna M. Rivera, Dong Young Kim, Judith Frydman, Michael J. Trnka, Eric Jan, Alma L. Burlingame, David J. Stanley, Raul Andino
Publikováno v:
Cell host & microbe, vol 24, iss 4
Summary The dicistrovirus, Cricket paralysis virus (CrPV) encodes an RNA interference (RNAi) suppressor, 1A, which modulates viral virulence. Using the Drosophila model, we combined structural, biochemical, and virological approaches to elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bbe9a164693cb974c2fd586e082944
https://europepmc.org/articles/PMC6450077/
https://europepmc.org/articles/PMC6450077/
Autor:
William F. DeGrado, Glenda M. Halliday, Stanley B. Prusiner, Sjoerd G. van Duinen, Amanda L. Woerman, Carlo Condello, Lars Lannfelt, Thomas D. Bird, Joanne C. Lee, Jan Stöhr, Atsushi Aoyagi, William W. Seeley, Caroline Graff, C. Dirk Keene, Brianna M. Rivera, Martin Ingelsson
Publikováno v:
Alzheimer's & Dementia. 14