Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brianna Hoffman"'
Autor:
Jeffrey R. Jones, Linghai Kong, Michael G. Hanna, IV, Brianna Hoffman, Robert Krencik, Robert Bradley, Tracy Hagemann, Jeea Choi, Matthew Doers, Marina Dubovis, Mohammad Amin Sherafat, Anita Bhattacharyya, Christina Kendziorski, Anjon Audhya, Albee Messing, Su-Chun Zhang
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 947-958.e4 (2018)
Summary: How mutations in glial fibrillary acidic protein (GFAP) cause Alexander disease (AxD) remains elusive. We generated iPSCs from two AxD patients and corrected the GFAP mutations to examine the effects of mutant GFAP on human astrocytes. AxD a
Externí odkaz:
https://doaj.org/article/8661b3e265394aa380281091f516e8d2
Autor:
Albee Messing, Anita Bhattacharyya, Jeea Choi, Anjon Audhya, Marina Dubovis, Michael G. Hanna, Jeffrey R. Jones, Robert Krencik, Matthew E. Doers, Brianna Hoffman, Tracy L. Hagemann, Robert A. Bradley, Mohammad Amin Sherafat, Su-Chun Zhang, Linghai Kong, Christina Kendziorski
Publikováno v:
Cell reports
Cell Reports, Vol 25, Iss 4, Pp 947-958.e4 (2018)
Cell Reports, Vol 25, Iss 4, Pp 947-958.e4 (2018)
SUMMARY How mutations in glial fibrillary acidic protein (GFAP) cause Alexander disease (AxD) remains elusive. We generated iPSCs from two AxD patients and corrected the GFAP mutations to examine the effects of mutant GFAP on human astrocytes. AxD as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d843baf9fe6e5266497b63adb8f830f
https://doi.org/10.1016/j.celrep.2018.09.083
https://doi.org/10.1016/j.celrep.2018.09.083
Autor:
Xiang Li, Yezheng Tao, Robert Bradley, Zhongwei Du, Yunlong Tao, Linghai Kong, Yi Dong, Jeffrey Jones, Yuanwei Yan, Cole R.K. Harder, Lindsay Morgan Friedman, Magd Bilal, Brianna Hoffmann, Su-Chun Zhang
Publikováno v:
Stem Cell Reports, Vol 11, Iss 4, Pp 998-1008 (2018)
Summary: Differentiation of astrocytes from human pluripotent stem cells (hPSCs) is a tedious and variable process. This hampers the study of hPSC-generated astrocytes in disease processes and drug development. By using CRISPR/Cas9-mediated inducible
Externí odkaz:
https://doaj.org/article/d7a591da868c47328917641f6b3c6cda