Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brianna H. Shares"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 3, Pp 24-24 (2019)
OBJECTIVES/SPECIFIC AIMS: The study aims to further investigate how cyclophilin D (CypD), the key mPTP opening regulator, affects BMSCs fate and to determine potential regulatory mechanisms involved in CypD regulation during osteogenesis. METHODS/STU
Externí odkaz:
https://doaj.org/article/7c6b232b3e6141c3a7713dc92a7c835e
Autor:
Ananta Paine, Gisela Beutner, Brianna H. Shares, Edward B. Brown, Hani A. Awad, Rubens Sautchuk, Charles O. Smith, Gira E, Tzong-Jen Sheu, Roman A. Eliseev, Kevin Schilling, Laura C. Shum
Bone fracture is accompanied by mechanical stresses and inflammation – conditions that impair mitochondria via the phenomenon of permeability transition. This phenomenon occurs due to opening of the mitochondrial permeability transition pore (MPTP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492dc3bc16de0270a60efa8b4e3aef5d
https://doi.org/10.1101/771691
https://doi.org/10.1101/771691
Autor:
Charles O. Smith, Edward B. Brown, Aric Huber, Roman A. Eliseev, Laura C. Shum, Kevin Schilling, Rubens Sautchuk, Tzong-Jen Sheu, Hani A. Awad, Emma Gira, Brianna H. Shares, Ananta Paine
Publikováno v:
Bone
Bone fracture is accompanied by trauma, mechanical stresses, and inflammation – conditions known to induce the mitochondrial permeability transition. This phenomenon occurs due to opening of the mitochondrial permeability transition pore (MPTP) pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9062416773f2c008b81f795578f97e2
https://doi.org/10.1016/j.bone.2020.115391
https://doi.org/10.1016/j.bone.2020.115391
Bone marrow stromal (a.k.a. mesenchymal stem) cells (BMSCs) can differentiate into osteoblasts (OBs), adipocytes, or chondrocytes. As BMSCs undergo OB differentiation, they up-regulate mitochondrial oxidative phosphorylation (OxPhos). Here, we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b67b86734f86444cc59ee0b74a9d4ff
https://europepmc.org/articles/PMC6187642/
https://europepmc.org/articles/PMC6187642/
Publikováno v:
Journal of Clinical and Translational Science
OBJECTIVES/SPECIFIC AIMS: The study aims to further investigate how cyclophilin D (CypD), the key mPTP opening regulator, affects BMSCs fate and to determine potential regulatory mechanisms involved in CypD regulation during osteogenesis. METHODS/STU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dc37371813fe7961542c82c63cd8e3
https://doi.org/10.1017/cts.2019.58
https://doi.org/10.1017/cts.2019.58