Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brianna Fernandez"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Senescence, a state of irreversible cell-cycle withdrawal, is difficult to distinguish from quiescence, a state of reversible cell-cycle withdrawal. This difficulty arises because quiescent and senescent cells are defined by overlapping biom
Externí odkaz:
https://doaj.org/article/cef1f2379a154bd2af8fcb70b3a73463
Autor:
Evan D. Muse, Shang-Fu Chen, Shuchen Liu, Brianna Fernandez, Brian Schrader, Bhuvan Molparia, André Nicolás León, Raymond Lee, Neha Pubbi, Nolan Mejia, Christina Ren, Ahmed El-kalliny, Ernesto Prado Montes de Oca, Hector Aguilar, Arjun Ghoshal, Raquel Dias, Doug Evans, Kai-Yu Chen, Yunyue Zhang, Nathan E. Wineinger, Emily G. Spencer, Eric J. Topol, Ali Torkamani
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-9 (2022)
Abstract We developed a smartphone application, MyGeneRank, to conduct a prospective observational cohort study (NCT03277365) involving the automated generation, communication, and electronic capture of response to a polygenic risk score (PRS) for co
Externí odkaz:
https://doaj.org/article/b864692d37b448dda555fd2e23d8986a
Autor:
Daniel Cunningham-Bryant, Brianna Fernandez, Jesse G. Zalatan, Emily R. Cliff, Joseph L. Harman, Robin L. Kirkpatrick
Publikováno v:
ACS Synth Biol
To investigate the relationship between genome structure and function, we have developed a programmable CRISPR-Cas system for nuclear peripheral recruitment in yeast. We benchmarked this system at the HMR and GAL2 loci, both of which are well-charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86f238d6b13d32983043608fb782097
https://europepmc.org/articles/PMC8627703/
https://europepmc.org/articles/PMC8627703/
Autor:
Evan D. Muse, Shang-Fu Chen, Shuchen Liu, Brianna Fernandez, Brian Schrader, Bhuvan Molparia, André Nicolás León, Raymond Lee, Neha Pubbi, Nolan Mejia, Christina Ren, Ahmed El-kalliny, Ernesto Prado Montes de Oca, Hector Aguilar, Arjun Ghoshal, Raquel Dias, Doug Evans, Kai-Yu Chen, Yunyue Zhang, Nathan E. Wineinger, Emily G. Spencer, Eric J. Topol, Ali Torkamani
Publikováno v:
NPJ digital medicine. 5(1)
We developed a smartphone application, MyGeneRank, to conduct a prospective observational cohort study (NCT03277365) involving the automated generation, communication, and electronic capture of response to a polygenic risk score (PRS) for coronary ar
Autor:
Emily R. Cliff, Robin L. Kirkpatrick, Jesse G. Zalatan, Brianna Fernandez, Daniel Cunningham-Bryant
To investigate the relationship between genome structure and function, we have developed a programmable CRISPR-Cas system for nuclear peripheral recruitment in yeast. We benchmarked this system at the HMR and GAL2 loci, both well-characterized model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80541b65871a0f8a1657f45e9ba151a8
https://doi.org/10.1101/2021.04.30.442211
https://doi.org/10.1101/2021.04.30.442211
Publikováno v:
Chembiochem : a European journal of chemical biology. 20(12)
Synthetic CRISPR-Cas transcription factors enable the construction of complex gene expression programs, and chemically-inducible systems allow precise control over the expression dynamics. To provide additional modes of regulatory control, we have co