Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Brianna A. Smith"'
Autor:
Ashwini K. Yenamandra, Rebecca B. Smith, Adam C. Seegmiller, Brianna N. Smith, Debra L. Friedman, Christine M. Smith
Publikováno v:
DNA, Vol 4, Iss 3, Pp 318-327 (2024)
Diffuse large B cell lymphoma, not otherwise specified (DLBCL, NOS) is the most common type of non-Hodgkin lymphoma (NHL). Significant efforts have been focused on utilizing advanced genomic technologies to further subclassify DLBCL, NOS into clinica
Externí odkaz:
https://doaj.org/article/d063c8b14ae9467abb03607aa4115a26
Autor:
Gregory Caleb Howard, Jing Wang, Kristie L Rose, Camden Jones, Purvi Patel, Tina Tsui, Andrea C Florian, Logan Vlach, Shelly L Lorey, Brian C Grieb, Brianna N Smith, Macey J Slota, Elizabeth M Reynolds, Soumita Goswami, Michael R Savona, Frank M Mason, Taekyu Lee, Stephen Fesik, Qi Liu, William P Tansey
Publikováno v:
eLife, Vol 12 (2024)
The chromatin-associated protein WD Repeat Domain 5 (WDR5) is a promising target for cancer drug discovery, with most efforts blocking an arginine-binding cavity on the protein called the ‘WIN’ site that tethers WDR5 to chromatin. WIN site inhibi
Externí odkaz:
https://doaj.org/article/843d9e309e8c4e569cdd20374b77da61
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 19, Iss 1, Pp 1-10 (2023)
Abstract Background COVID-19 disproportionately affects those with preexisting conditions, but little research has determined whether those with chronic diseases view the pandemic itself differently - and whether there are differences between chronic
Externí odkaz:
https://doaj.org/article/fc3d8b4e53464a37990f40b41fde332d
Autor:
Haley E. Ramsey, Agnieszka E. Gorska, Brianna N. Smith, Andrew J. Monteith, Londa Fuller, Maria P. Arrate, Michael R. Savona
Publikováno v:
Haematologica, Vol 999, Iss 1 (2023)
CD47-SIRPa is a myeloid check point pathway that inhibits phagocytosis of cells lacking markers for self-recognition. Tumor cells can overexpress CD47 and bind to SIRPa on macrophages, preventing phagocytosis. CD47 expression is enhanced and correlat
Externí odkaz:
https://doaj.org/article/a5d6642b97a7419d8495b6ce1990441f
Autor:
Melissa A. Fischer, Yuanbin Song, Maria P. Arrate, Rana Gbyli, Matthew T. Villaume, Brianna N. Smith, Merrida A. Childress, Thomas P. Stricker, Stephanie Halene, Michael R. Savona
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Treatment for myelodysplastic syndromes (MDS) remains insufficient due to clonal heterogeneity and lack of effective clinical therapies. Dysregulation of apoptosis is observed across MDS subtypes regardless of mutations and represents an attractive t
Externí odkaz:
https://doaj.org/article/59613419e2c2473984ff9a5e86775d97
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
CRISPR-Cas12a based detection systems can be sensitive down to the picomolar range. Here the authors modify the 3′- and 5′-ends of the crRNA and show this enhances trans-cleavage for improved sensitivity.
Externí odkaz:
https://doaj.org/article/de5c4909e62841dd937390825877c68b
Autor:
Dan Cojocari, Brianna N. Smith, Julie J. Purkal, Maria P. Arrate, Jason D. Huska, Yu Xiao, Agnieszka Gorska, Leah J. Hogdal, Haley E. Ramsey, Erwin R. Boghaert, Darren C. Phillips, Michael R. Savona
Publikováno v:
Haematologica, Vol 107, Iss 4 (2021)
Dysregulation of apoptotic machinery is one mechanism by which acute myeloid leukemia (AML) acquires a clonal survival advantage. B-cell lymphoma protein-2 (BCL2) overexpression is a common feature in hematologic malignancies. The selective BCL2 inhi
Externí odkaz:
https://doaj.org/article/fcbff983b81140129e1223aefa05499e
Publikováno v:
Journal of Family Trauma, Child Custody & Child Development. 19:402-416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed308eb48b2ed7196be0ead9c44de584
https://doi.org/10.1080/26904586.2022.2066595
https://doi.org/10.1080/26904586.2022.2066595
Publikováno v:
Journal of Experimental Political Science. 10:21-33
The American reaction to the COVID-19 pandemic is polarized, with conservatives often less willing to engage in risk-mitigation strategies such as mask-wearing and vaccination. COVID-19 narratives are also polarized, as some conservative elites focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7177079e9f1ff5dd9e4f5cc076f36382
https://doi.org/10.1017/xps.2022.6
https://doi.org/10.1017/xps.2022.6
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20117-z
Externí odkaz:
https://doaj.org/article/fd8478c6f5db4766997805b36a0b1d9d