Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Briana Spolding"'
Autor:
Trang TT. Truong, Chiara C. Bortolasci, Briana Spolding, Bruna Panizzutti, Zoe SJ. Liu, Srisaiyini Kidnapillai, Mark Richardson, Laura Gray, Craig M. Smith, Olivia M. Dean, Jee Hyun Kim, Michael Berk, Ken Walder
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Long non-coding RNAs (lncRNAs) may play a role in psychiatric diseases including bipolar disorder (BD). We investigated mRNA-lncRNA co-expression patterns in neuronal-like cells treated with widely prescribed BD medications. The aim was to unveil ins
Externí odkaz:
https://doaj.org/article/1b7db7b99d394d6a8ba7f29dfa0e8f8f
Autor:
Trang T. T. Truong, Chiara C. Bortolasci, Srisaiyini Kidnapillai, Briana Spolding, Bruna Panizzutti, Zoe S. J. Liu, Jee Hyun Kim, Olivia M. Dean, Mark F. Richardson, Michael Berk, Ken Walder
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7508 (2022)
There is little understanding of the underlying molecular mechanism(s) involved in the clinical efficacy of antipsychotics for schizophrenia. This study integrated schizophrenia-associated transcriptional perturbations with antipsychotic-induced gene
Externí odkaz:
https://doaj.org/article/44c12c8946514f9bafad2f1307382fce
Autor:
Zoe S. J. Liu, Trang T. T. Truong, Chiara C. Bortolasci, Briana Spolding, Bruna Panizzutti, Courtney Swinton, Jee Hyun Kim, Srisaiyini Kidnapillai, Mark F. Richardson, Laura Gray, Olivia M. Dean, Sean L. McGee, Michael Berk, Ken Walder
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7180 (2022)
Altered protein synthesis has been implicated in the pathophysiology of several neuropsychiatric disorders, particularly schizophrenia. Ribosomes are the machinery responsible for protein synthesis. However, there remains little information on whethe
Externí odkaz:
https://doaj.org/article/4474d965ae014f8eb0c03d92a04e2d92
Autor:
Bruna Panizzutti, Chiara C. Bortolasci, Briana Spolding, Srisaiyini Kidnapillai, Timothy Connor, Mark F. Richardson, Trang T. T. Truong, Zoe S. J. Liu, Laura Gray, Jee Hyun Kim, Olivia M. Dean, Michael Berk, Ken Walder
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 18, p 4095 (2021)
Weight gain and consequent metabolic alterations are common side-effects of many antipsychotic drugs. Interestingly, several studies have suggested that improvement in symptoms and adverse metabolic effects are correlated. We used next generation seq
Externí odkaz:
https://doaj.org/article/ebb4464f683e46209a8b4d268ac18ac7
Autor:
Bruna Panizzutti, Chiara C. Bortolasci, Briana Spolding, Srisaiyini Kidnapillai, Timothy Connor, Mark F. Richardson, Trang T. T. Truong, Zoe S. J. Liu, Gerwyn Morris, Laura Gray, Jee Hyun Kim, Olivia M. Dean, Michael Berk, Ken Walder
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7164 (2021)
Recent reports suggest a link between positive regulation of the Hippo pathway with bipolar disorder (BD), and the Hippo pathway is known to interact with multiple other signaling pathways previously associated with BD and other psychiatric disorders
Externí odkaz:
https://doaj.org/article/bf46b7c355d64b9a825ab2cc7540a34e
Autor:
Chiara C. Bortolasci, Briana Spolding, Srisaiyini Kidnapillai, Timothy Connor, Trang T.T. Truong, Zoe S.J. Liu, Bruna Panizzutti, Mark F. Richardson, Laura Gray, Michael Berk, Olivia M. Dean, Ken Walder
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8333 (2020)
Although neurogenesis is affected in several psychiatric diseases, the effects and mechanisms of action of psychoactive drugs on neurogenesis remain unknown and/or controversial. This study aims to evaluate the effects of psychoactive drugs on the ex
Externí odkaz:
https://doaj.org/article/9756fab77f5b4a568ed7f9b95f6d5f4b
Autor:
Briana Spolding, Timothy Connor, Carrie Wittmer, Lelia L F Abreu, Antony Kaspi, Mark Ziemann, Gunveen Kaur, Adrian Cooper, Shona Morrison, Scott Lee, Andrew Sinclair, Yann Gibert, James L Trevaskis, Jonathon D Roth, Assam El-Osta, Richard Standish, Ken Walder
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92656 (2014)
BACKGROUND AND AIMS: A major impediment to establishing new treatments for non-alcoholic steatohepatitis is the lack of suitable animal models that accurately mimic the biochemical and metabolic characteristics of the disease. The aim of this study w
Externí odkaz:
https://doaj.org/article/13a67a5e3d2a4746890cfefb42e46c36
Autor:
Chiara C. Bortolasci, Srisaiyini Kidnapillai, Briana Spolding, Trang T. T. Truong, Timothy Connor, Courtney Swinton, Bruna Panizzutti, Zoe S. J. Liu, Andrew Sanigorski, Olivia M. Dean, Tamsyn Crowley, Mark Richardson, Kiymet Bozaoglu, Katerina Vlahos, Stephanie Cowdery, Brad Watmuff, Stephan F. Steyn, De Wet Wolmarans, Barend J. Engelbrecht, Christina Perry, Katherine Drummond, Terence Pang, Stéphane Jamain, Laura Gray, Sean L. McGee, Brian H. Harvey, Jee Hyun Kim, Marion Leboyer, Michael Berk, Ken Walder
Publikováno v:
Bipolar Disorders.
Autor:
Olivia M Dean, Lauren Arancini, Michael Berk, Chiara C. Bortolasci, Briana Spolding, Robson Zazula, Seetal Dodd, Mohammadreza Mohebbi
Publikováno v:
European Neuropsychopharmacology. 53:120-126
Smoking represents a significant health threat to the population, however there remains a core group of consistent smokers that are largely unable to break the addiction. Novel therapies are required to assist this group with cessation. N-acetylcyste
Autor:
Jacqueline Lake, Chiara C. Bortolasci, Amanda L. Stuart, Julie A. Pasco, Srisaiyini Kidnapillai, Briana Spolding, Trang T. T. Truong, Bruna Panizzutti, Zoe S. J. Liu, Olivia M. Dean, Tamsyn Crowley, Mark Richardson, Jee Hyun Kim, Michael Berk, Lana J. Williams, Ken Walder
Publikováno v:
Pharmacopsychiatry. 56(1)
Introduction Mood disorders are a major cause of disability, and current treatment options are inadequate for reducing the burden on a global scale. The aim of this project was to identify drugs suitable for repurposing to treat mood disorders. Metho