Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Briana Prager"'
Autor:
Sajina Shakya, Anthony D. Gromovsky, James S. Hale, Arnon M. Knudsen, Briana Prager, Lisa C. Wallace, Luiz O. F. Penalva, H. Alex Brown, Bjarne W. Kristensen, Jeremy N. Rich, Justin D. Lathia, J. Mark Brown, Christopher G. Hubert
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has long been advocated as a therapy against many tumors including GBM, but how lipid me
Externí odkaz:
https://doaj.org/article/f740fb738c5c45e4ad68a8ab8f9b28c9
Autor:
Junfeng Bi, Atif Khan, Jun Tang, Aaron M. Armando, Sihan Wu, Wei Zhang, Ryan C. Gimple, Alex Reed, Hui Jing, Tomoyuki Koga, Ivy Tsz-Lo Wong, Yuchao Gu, Shunichiro Miki, Huijun Yang, Briana Prager, Ellis J. Curtis, Derek A. Wainwright, Frank B. Furnari, Jeremy N. Rich, Timothy F. Cloughesy, Harley I. Kornblum, Oswald Quehenberger, Andrey Rzhetsky, Benjamin F. Cravatt, Paul S. Mischel
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109957- (2021)
Summary: The highly lethal brain cancer glioblastoma (GBM) poses a daunting challenge because the blood-brain barrier renders potentially druggable amplified or mutated oncoproteins relatively inaccessible. Here, we identify sphingomyelin phosphodies
Externí odkaz:
https://doaj.org/article/8516b7196aa84c49af33aefb9f94a103
Publikováno v:
Cancer Research. 80:CT053-CT053
Natural killer (NK) cells play a key role in tumor immune surveillance by their ability to recognize and kill both hematological and solid tumor cells. NK cell-based immunotherapy is emerging as a powerful treatment against certain malignancies. Howe