Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Briana M. Bohannon"'
Autor:
Briana M Bohannon, Jessica J Jowais, Leif Nyberg, Vanessa Olivier-Meo, Valentina Corradi, D Peter Tieleman, Sara I Liin, H Peter Larsson
Publikováno v:
eLife, Vol 12 (2023)
Voltage-gated potassium (KV) channels are important regulators of cellular excitability and control action potential repolarization in the heart and brain. KV channel mutations lead to disordered cellular excitability. Loss-of-function mutations, for
Externí odkaz:
https://doaj.org/article/7551a63ea06f42c399ecf18db23a441f
Autor:
Briana M Bohannon, Alicia de la Cruz, Xiaoan Wu, Jessica J Jowais, Marta E Perez, Derek M Dykxhoorn, Sara I Liin, H Peter Larsson
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/916e39ef8eff457f849713b47ca7bd82
Autor:
Briana M Bohannon, Alicia de la Cruz, Xiaoan Wu, Jessica J Jowais, Marta E Perez, Derek M Dykxhoorn, Sara I Liin, H Peter Larsson
Publikováno v:
eLife, Vol 9 (2020)
The cardiac ventricular action potential depends on several voltage-gated ion channels, including NaV, CaV, and KV channels. Mutations in these channels can cause Long QT Syndrome (LQTS) which increases the risk for ventricular fibrillation and sudde
Externí odkaz:
https://doaj.org/article/e07a4e0605884ed9905949525bae0d17
Voltage-gated potassium (KV) channels are important regulators of cellular excitability and control action potential repolarization in the heart and brain. KVchannel mutations lead to disordered cellular excitability. Loss-of-function mutations, for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03986ba4b524b6f111dc26714b02f583
https://doi.org/10.1101/2023.01.12.523777
https://doi.org/10.1101/2023.01.12.523777
Autor:
Jessica J Jowais, Marta E. Perez, Sara I. Liin, Derek M. Dykxhoorn, Briana M. Bohannon, Alicia de la Cruz, Xiaoan Wu, H. Peter Larsson
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f243245d8387bae81e059ab8b77194
https://elifesciences.org/articles/60141
https://elifesciences.org/articles/60141
Autor:
Sara I. Liin, Jessica J Jowais, Derek M. Dykxhoorn, Xiaoan Wu, Marta E. Perez, Briana M. Bohannon, Hans Peter Larsson, Alicia de la Cruz
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The cardiac ventricular action potential depends on several voltage-gated ion channels, including Na-V, Ca-V, and K-V channels. Mutations in these channels can cause Long QT Syndrome (LQTS) which increases the risk for ventricular fibrillation and su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32aacfc3b510bd4c28f8e2c2bc0f1f3
https://elifesciences.org/articles/51453
https://elifesciences.org/articles/51453
Publikováno v:
The Journal of General Physiology
Bohannon et al. show that polyunsaturated fatty acids (PUFAs) vary in their ability to activate cardiac IKs potassium channels depending on the pKa of the PUFA head group, allowing PUFAs to be tuned to treat long QT syndrome mutants with different di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444d4b1e34f90f791c76290645654b5a
https://doi.org/10.1085/jgp.201912396
https://doi.org/10.1085/jgp.201912396
The cardiac ventricular action potential depends on several voltage-gated ion channels, including Nav, Cav, and Kv channels. Mutations in these channels can cause Long QT Syndrome (LQTS) which increases the risk for ventricular fibrillation and sudde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf5543e9c2918be1c33bf82b85c0f6e
Aim The I-Ks channel is important for termination of the cardiac action potential. Hundreds of loss-of-function mutations in the I-Ks channel reduce the K+ current and, thereby, delay the repolarization of the action potential, causing Long QT Syndro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcb307ebdee779cb4a46d74d4a06b04
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-154317
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-154317