Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Brian Y. Lee"'
Autor:
Brian Y. Lee, Elizabeth K. J. Hogg, Christopher R. Below, Alexander Kononov, Adrian Blanco-Gomez, Felix Heider, Jingshu Xu, Colin Hutton, Xiaohong Zhang, Tamara Scheidt, Kenneth Beattie, Angela Lamarca, Mairéad McNamara, Juan W. Valle, Claus Jørgensen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Cancer-associated fibroblasts (CAFs) are a major component of the desmoplastic stroma in pancreatic ductal adenocarcinoma (PDA). Here the authors report the importance of macrophage-derived Oncostatin M in reprogramming CAFs to drive a pro-tumorigeni
Externí odkaz:
https://doaj.org/article/3b444973af7e4c88bad9060cb4eb9f37
Autor:
Janet Y. Sheung, Jonathan Garamella, Stella K. Kahl, Brian Y. Lee, Ryan J. McGorty, Rae M. Robertson-Anderson
Publikováno v:
Frontiers in Physics, Vol 10 (2022)
The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion
Externí odkaz:
https://doaj.org/article/c03d9bcfe6fa490691312c3697008152
Autor:
Roger J. Daly, Lisa G. Horvath, S. Martin Shreeve, Mark J. Raftery, Jianmin Wu, Lesley Castillo, Hui-Ming Lin, Falko Hochgräfe, Brian Y. Lee
PDF - 260KB, Supplementary Figure 1. Validation of the Docetaxel-resistant prostate cancer cell line DU145-Rx. Supplementary Figure 1. Validation of the Docetaxel-resistant prostate cancer cell line DU145-Rx. Supplementary Figure 3. Co-treatment-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fa43c1d3d8e394aca4294dd847528c
https://doi.org/10.1158/1535-7163.22504215
https://doi.org/10.1158/1535-7163.22504215
Autor:
Lisa G. Horvath, Susan M. Henshall, Robert L. Sutherland, Samuel N. Breit, Warren Kaplan, Martin R. Stockler, Michael J. Boyer, Nick Pavlakis, Gavin M. Marx, Mark P. Molloy, David A. Brown, Brian Y. Lee, Liangli Zhao
Docetaxel chemotherapy improves symptoms and survival in men with metastatic hormone-refractory prostate cancer (HRPC). However, ∼50% of patients do not respond to Docetaxel and are exposed to significant toxicity without direct benefit. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::833c172d49d8815ba862917d16b152f9
https://doi.org/10.1158/0008-5472.c.6499137.v1
https://doi.org/10.1158/0008-5472.c.6499137.v1
Autor:
Lisa G. Horvath, Susan M. Henshall, Robert L. Sutherland, Samuel N. Breit, Warren Kaplan, Martin R. Stockler, Michael J. Boyer, Nick Pavlakis, Gavin M. Marx, Mark P. Molloy, David A. Brown, Brian Y. Lee, Liangli Zhao
Supplementary Table 1 from Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68454b64d1796e9cf06b72d460cd8400
https://doi.org/10.1158/0008-5472.22379100.v1
https://doi.org/10.1158/0008-5472.22379100.v1
Autor:
Lisa G. Horvath, Susan M. Henshall, Robert L. Sutherland, Samuel N. Breit, Warren Kaplan, Martin R. Stockler, Michael J. Boyer, Nick Pavlakis, Gavin M. Marx, Mark P. Molloy, David A. Brown, Brian Y. Lee, Liangli Zhao
Supplementary Figure 2 from Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e3ddc436f903cb0ef9f1c268a6b4e7
https://doi.org/10.1158/0008-5472.22379106.v1
https://doi.org/10.1158/0008-5472.22379106.v1
Autor:
Lisa G. Horvath, Susan M. Henshall, Robert L. Sutherland, Samuel N. Breit, Warren Kaplan, Martin R. Stockler, Michael J. Boyer, Nick Pavlakis, Gavin M. Marx, Mark P. Molloy, David A. Brown, Brian Y. Lee, Liangli Zhao
Supplementary Figure Legends 1-2, Table Legend from Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df897a187e52aff0da6b1302f451419
https://doi.org/10.1158/0008-5472.22379103
https://doi.org/10.1158/0008-5472.22379103
Autor:
Lisa G. Horvath, Susan M. Henshall, Robert L. Sutherland, Samuel N. Breit, Warren Kaplan, Martin R. Stockler, Michael J. Boyer, Nick Pavlakis, Gavin M. Marx, Mark P. Molloy, David A. Brown, Brian Y. Lee, Liangli Zhao
Supplementary Figure 1 from Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42eb6108afd3e636d4ae3f724da28fe
https://doi.org/10.1158/0008-5472.22379109
https://doi.org/10.1158/0008-5472.22379109
Autor:
Christopher Below, Joanna Kelly, Alexander Brown, Jonathan D. Humphries, Colin Hutton, Jingshu Xu, Brian Y. Lee, Celia Cintas, Xiaohong Zhang, Victor Hernandez-Gordillo, Janet Askari, Jessica Burns, Linda Stockdale, Matthew A. Goldsworthy, Joe Geraghty, Lucy Foster, Derek A. O'Reilly, Barbara Schedding, Nigel Hodson, Duncan Smith, Catherine Lally, Garry Ashton, David Knight, Aleksandr Mironov, Antonia Banyard, Johannes A Eble, Jennifer P. Morton, Martin J. Humphries, Linda G. Griffith, Claus Jørgensen
Experimental in vitro models that accurately capture pathophysiological characteristics of human tumours are essential for basic and translational cancer biology. Here, we describe a fully synthetic hydrogel extracellular matrix, specifically designe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e48cf8fbdc8e9d8e315d99e3fd60199
Autor:
Nicole K. Yeung, Brian Y. Lee, S. Martin Shreeve, Hui-Ming Lin, Anne Maree Haynes, Phillip D. Stricker, Calan Spielman, Margaret M. Centenera, Lisa M. Butler, Lisa G. Horvath, Judith Grogan, Roger J. Daly, Lesley Castillo, James G. Kench
Publikováno v:
The Prostate. 78:308-317
Background Docetaxel, the standard chemotherapy for metastatic castration-resistant prostate cancer (CRPC) also enhances the survival of patients with metastatic castration-sensitive prostate cancer (CSPC) when combined with androgen-deprivation ther