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Autor:
Keith Sides, James Pribish, Magali Mathieu, Sam Rebello, Gregory H. Merriman, Henry W. Pauls, Guyan Liang, Xin Chen, Julian Levell, Jennifer Cairns, Isabelle Morize, Brian Whitely, Joseph T. Tsay, Aldous Suzanne C, Sébastien Maignan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1049-1054
A solid phase combinatorial library was designed based on X-ray structures and in-silico models to explore an inducible S4+ pocket, which is formed by a simple side-chain rotation of Tyr95. This inducible S4+ pocket is unique to β-tryptase and does
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f671f9914d4892d516d5bdd70e540e8f
https://doi.org/10.1016/j.bmcl.2011.11.119
https://doi.org/10.1016/j.bmcl.2011.11.119
