Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Brian W. Rous"'
Autor:
John S. Magyar, John C. Payne, Gerard Parkin, David F. Dye, James E. Penner-Hahn, Jeffrey M. Zaleski, Brian M. Bridgewater, Charlotte M. Stern, Hilary A. Godwin, Brian W. Rous, Ana Mijovilovich, O Tsu-Chien Weng
Recent studies suggest that the developmental toxicity associated with childhood lead poisoning may be attributable to interactions of Pb(II) with proteins containing thiol-rich structural zinc-binding sites. Here, we report detailed structural studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a46b925295a79324fa85fe445d8eee
https://resolver.caltech.edu/CaltechAUTHORS:20170427-083925553
https://resolver.caltech.edu/CaltechAUTHORS:20170427-083925553
Publikováno v:
Biochemistry. 42(48)
Zinc binding to the two Cys(4) sites present in the DNA-binding domain (DBD) of nuclear hormone receptor proteins is required for proper folding of the domain and for protein activity. By utilizing Co(2+) as a spectroscopic probe, we have characteriz