Výsledky vyhledávání - "Brian W Davis"

Akademický článek

Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci

Autor: Fan Han, Minal Jamsandekar, Mats E Pettersson, Leyi Su, Angela P Fuentes-Pardo, Brian W Davis, Dorte Bekkevold, Florian Berg, Michele Casini, Geir Dahle, Edward D Farrell, Arild Folkvord, Leif Andersson

Publikováno v: eLife, Vol 9 (2020)

Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to minute genetic differentiation at selectively neutral loci. He

Externí odkaz: https://doaj.org/article/3c6b5aa30c8647b1b2d3595d9657903e

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Akademický článek

A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism.

Autor: Reuben M Buckley, Brian W Davis, Wesley A Brashear, Fabiana H G Farias, Kei Kuroki, Tina Graves, LaDeana W Hillier, Milinn Kremitzki, Gang Li, Rondo P Middleton, Patrick Minx, Chad Tomlinson, Leslie A Lyons, William J Murphy, Wesley C Warren

Publikováno v: PLoS Genetics, Vol 16, Iss 10, p e1008926 (2020)

The domestic cat (Felis catus) numbers over 94 million in the USA alone, occupies households as a companion animal, and, like humans, suffers from cancer and common and rare diseases. However, genome-wide sequence variant information is limited for t

Externí odkaz: https://doaj.org/article/f66873bec5b54e57a16b45a9e350d059

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Akademický článek

The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring

Autor: Minal Jamsandekar, Mafalda S. Ferreira, Mats E. Pettersson, Edward D. Farrell, Brian W. Davis, Leif Andersson

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Abstract Chromosomal inversions are associated with local adaptation in many species. However, questions regarding how they are formed, maintained and impact various other evolutionary processes remain elusive. Here, using a large genomic dataset of

Externí odkaz: https://doaj.org/article/55bbfc9ad98d47a296383c18ff46dd21

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Akademický článek

Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness.

Autor: Jocelyn Plassais, Maud Rimbault, Falina J Williams, Brian W Davis, Jeffrey J Schoenebeck, Elaine A Ostrander

Publikováno v: PLoS Genetics, Vol 13, Iss 3, p e1006661 (2017)

Domestic dog breeds display significant diversity in both body mass and skeletal size, resulting from intensive selective pressure during the formation and maintenance of modern breeds. While previous studies focused on the identification of alleles

Externí odkaz: https://doaj.org/article/9f1e839f0ebc4e40a75bd1154ac998ce

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Akademický článek

An intronic copy number variation in Syntaxin 17 determines speed of greying and melanoma incidence in Grey horses

Autor: Carl-Johan Rubin, McKaela Hodge, Rakan Naboulsi, Madeleine Beckman, Rebecca R. Bellone, Angelica Kallenberg, Stephanie J’Usrey, Hajime Ohmura, Kazuhiro Seki, Risako Furukawa, Aoi Ohnuma, Brian W. Davis, Teruaki Tozaki, Gabriella Lindgren, Leif Andersson

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)

Abstract The Greying with age phenotype in horses involves loss of hair pigmentation whereas skin pigmentation is not reduced, and a predisposition to melanoma. The causal mutation was initially reported as a duplication of a 4.6 kb intronic sequence

Externí odkaz: https://doaj.org/article/6d1e89a9321a4cff8fdffdebfd0b73fa

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Akademický článek

Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs.

Publikováno v: PLoS Genetics, Vol 12, Iss 3, p e1005851 (2016)

Controlling for background demographic effects is important for accurately identifying loci that have recently undergone positive selection. To date, the effects of demography have not yet been explicitly considered when identifying loci under select

Externí odkaz: https://doaj.org/article/73f7b6a47b734c7b8753485838c3cece

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Akademický článek

Proteomic analysis of sperm from fertile stallions and subfertile stallions due to impaired acrosomal exocytosis

Autor: Camilo Hernández-Avilés, Luisa Ramírez-Agámez, Susan T. Weintraub, Charles F. Scoggin, Brian W. Davis, Terje Raudsepp, Dickson D. Varner, Charles C. Love

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Thoroughbred stallions that carry a double-homozygous genotype A/A-A/A for SNPs rs397316122 and rs69101140 in exon 5 of the FKBP6 gene (chr13; EquCab3.0) are uniquely subfertile due to impaired acrosomal exocytosis (IAE). In this study, the

Externí odkaz: https://doaj.org/article/24ec28fad45d4cac88cfe0dada331666

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Akademický článek

Trio-binning of a hinny refines the comparative organization of the horse and donkey X chromosomes and reveals novel species-specific features

Autor: Matthew J. Jevit, Caitlin Castaneda, Nandina Paria, Pranab J. Das, Donald Miller, Douglas F. Antczak, Theodore S. Kalbfleisch, Brian W. Davis, Terje Raudsepp

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract We generated single haplotype assemblies from a hinny hybrid which significantly improved the gapless contiguity for horse and donkey autosomal genomes and the X chromosomes. We added over 15 Mb of missing sequence to both X chromosomes, 60

Externí odkaz: https://doaj.org/article/7a3a7eeafa724ef084ff3d2841a5a4f2

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