Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Brian W, Wong"'
Autor:
Zhiyi Liu, Fuyi Liao, Jihong Zhu, Dequan Zhou, Gyu Seong Heo, Hannah P. Leuhmann, Davide Scozzi, Antanisha Parks, Ramsey Hachem, Derek E. Byers, Laneshia K. Tague, Hrishikesh S. Kulkarni, Marlene Cano, Brian W. Wong, Wenjun Li, Howard J. Huang, Alexander S. Krupnick, Daniel Kreisel, Yongjian Liu, Andrew E. Gelman
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an immunomodulatory therapy that shows promise in stabilizing BOS patients,
Externí odkaz:
https://doaj.org/article/0ccd9c3986a04f8c80494fe161c5497a
Autor:
Yuehui Zhu, Hao Dun, Li Ye, Yuriko Terada, Leah P. Shriver, Gary J. Patti, Daniel Kreisel, Andrew E. Gelman, Brian W. Wong
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Monocytes play an important role in the regulation of alloimmune responses after heart transplantation (HTx). Recent studies have highlighted the importance of immunometabolism in the differentiation and function of myeloid cells. While the importanc
Externí odkaz:
https://doaj.org/article/c19029f8401e4fd9bb0af007c2d13bf8
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0230649 (2020)
BackgroundAllograft vasculopathy (AV) remains a major obstacle to long-term allograft survival. While the mouse aortic transplantation model has been proven as a useful tool for study of the pathogenesis of AV, simultaneous transplantation of the aor
Externí odkaz:
https://doaj.org/article/5a113d37716944db9f28ade8395be7f7
Autor:
Bert Cruys, Brian W. Wong, Anna Kuchnio, Dries Verdegem, Anna Rita Cantelmo, Lena-Christin Conradi, Saar Vandekeere, Ann Bouché, Ivo Cornelissen, Stefan Vinckier, Roeland M. H. Merks, Elisabetta Dejana, Holger Gerhardt, Mieke Dewerchin, Katie Bentley, Peter Carmeliet
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Glycolytic regulator PFKFB3 is a key player in vessel sprouting. Here the authors develop a computational model predicting that PFKFB3 drives endothelial cell rearrangement during vessel sprouting by promoting filopodia formation and reducing interce
Externí odkaz:
https://doaj.org/article/f168b79c697d4569b921c383b7c0a3c0
Autor:
Cliona O'Farrelly, Brian W. Wong, Min Xu, Ola Ahmed, Yiing Lin, Alexander N Wein, Fangyu Zhou, William C. Chapman, Gundumi A. Upadhya, Li Ye
Publikováno v:
American Journal of Transplantation. 22:58-70
Antioxidant defence mechanisms, such as the nuclear factor-erythroid 2-related-factor-2 (NRF2) axis, are integral to oxidative stress responses and ischemic injury. Hepatic antioxidant capacity is contingent on parenchymal quality, and there is a nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d609272c1481e899ac2fa526565ec9
https://doi.org/10.1111/ajt.16789
https://doi.org/10.1111/ajt.16789
Autor:
Renee Wu, Ray A. Ohara, Suin Jo, Tian-Tian Liu, Stephen T. Ferris, Feiya Ou, Sunkyung Kim, Derek J. Theisen, David A. Anderson, Brian W. Wong, Timothy Gershon, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Publikováno v:
Nat Immunol
CD40 signaling in classical type 1 dendritic cells (cDC1s) is required for CD8 T cell-mediated tumor rejection, but the underlying mechanisms are incompletely understood. Here, we identified CD40-induced genes in cDC1s, including Cd70, Tnfsf9, Ptgs2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73098e06eb50c5f3184eb4070018f0b1
https://europepmc.org/articles/PMC9896965/
https://europepmc.org/articles/PMC9896965/
Autor:
Brian W. Wong
Publikováno v:
American Journal of Transplantation. 20:1992-2000
With the recent advances in our understanding of the function and biology of the lymphatic vascular system, it is clear that the lymphatic system plays an integral role in physiology, and in pathological settings, may contribute to either enhance or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9cc87972a6567959e6a689ebe171786
https://doi.org/10.1111/ajt.15806
https://doi.org/10.1111/ajt.15806
Autor:
Yuehui Zhu, Hao Dun, Li Ye, Yuriko Terada, Leah P. Shriver, Gary J. Patti, Daniel Kreisel, Andrew E. Gelman, Brian W. Wong
Monocytes play an important role in the regulation of alloimmune responses after heart transplantation (HTx). Recent studies have highlighted the importance of immunometabolism in the differentiation and function of myeloid cells. While the importanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb4aec895577b08c4654c62973529a92
https://doi.org/10.1101/2022.02.09.479789
https://doi.org/10.1101/2022.02.09.479789
Autor:
Renee, Wu, Ray A, Ohara, Suin, Jo, Tian-Tian, Liu, Stephen T, Ferris, Feiya, Ou, Sunkyung, Kim, Derek J, Theisen, David A, Anderson, Brian W, Wong, Timothy, Gershon, Robert D, Schreiber, Theresa L, Murphy, Kenneth M, Murphy
Publikováno v:
Nature immunology. 23(11)
CD40 signaling in classical type 1 dendritic cells (cDC1s) is required for CD8 T cell-mediated tumor rejection, but the underlying mechanisms are incompletely understood. Here, we identified CD40-induced genes in cDC1s, including Cd70, Tnfsf9, Ptgs2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0af5605f55e6f5a1b9fe75f0f2d35a7
https://pubmed.ncbi.nlm.nih.gov/36271150
https://pubmed.ncbi.nlm.nih.gov/36271150
Autor:
Jianwei Xing, Li Ye, Min Xu, Jae-Sung Kim, Zhengyan Zhang, Yiing Lin, Gundumi A. Upadhya, Ola Ahmed, Kathleen Byrnes, So Hee Shim, Choonghee Lee, Fangyu Zhou, Brian W. Wong, William C. Chapman, Jianluo Jia
Publikováno v:
Transplantation
BACKGROUND Hepatic steatosis is now the leading cause of liver discards in deceased donors. Previous studies [Yarmush formula (Y) defatting] have successfully reduced the fat content by treating rat steatotic livers on extracorporeal normothermic mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d75660a2bfeb74a53fc4010e9b9432
https://europepmc.org/articles/PMC8356968/
https://europepmc.org/articles/PMC8356968/