Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Brian W, LeBlanc"'
Autor:
Nicholas A. Schmitz, Ritesh P. Thakare, Chun-Shiang Chung, Chang-Min Lee, Jack A. Elias, Chun Geun Lee, Brian W. LeBlanc
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mammalian cells do not produce chitin, an insoluble polymer of N-acetyl-D-glucosamine (GlcNAc), although chitin is a structural component of the cell wall of pathogenic microorganisms such as Candida albicans. Mammalian cells, including cells of the
Externí odkaz:
https://doaj.org/article/8e7c9cc3d9564937a46eab27077eb84e
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Paresthesia, a common feature of epidural spinal cord stimulation (SCS) for pain management, presents a challenge to the double-blind study design. Although sub-paresthesia SCS has been shown to be effective in alleviating pain, empirical cr
Externí odkaz:
https://doaj.org/article/a9111833c1f940ad87b61fc53d6ca57d
Autor:
Catherine M. Dickinson, Brian W. LeBlanc, Muhammad M. Edhi, Daithi S. Heffernan, Mohd. Hafeez Faridi, Vineet Gupta, William G. Cioffi, Xian O’Brien, Jonathan S. Reichner
Publikováno v:
Journal of Intensive Care, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Background Multi-organ failure occurs during critical illness and is mediated in part by destructive neutrophil-to-endothelial interactions. The β2 integrin receptor, CR3 (complement receptor 3; Mac-1; CD11b/CD18), which binds endothelial i
Externí odkaz:
https://doaj.org/article/8ed77ccae653466eadf09e0eeeb3f743
Autor:
Brian W. LeBlanc, Brent Cross, Kelsey A. Smith, Catherine Roach, Jimmy Xia, Yu-Chieh Chao, Joshua Levitt, Suguru Koyama, Christopher I. Moore, Carl Y. Saab
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract We tested the relation between pain behavior, theta (4–8 Hz) oscillations in somatosensory cortex and burst firing in thalamic neurons in vivo. Optically-induced thalamic bursts attenuated cortical theta and mechanical allodynia. It is pro
Externí odkaz:
https://doaj.org/article/1294ec178cf74cba946d2b0729643c9a
Autor:
Brian W, LeBlanc, Craig T, Lefort
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2321
The rapid innate immune response to respiratory infection is essential to prevent the systemic dissemination of pathogens. This chapter outlines an experimental mouse model of respiratory infection by gram-negative Pseudomonas aeruginosa and analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1d9547e4504514527fe77cf3c45a067
https://pubmed.ncbi.nlm.nih.gov/34048007
https://pubmed.ncbi.nlm.nih.gov/34048007
Autor:
Brian W. LeBlanc, Craig T. Lefort
Publikováno v:
Methods in Molecular Biology ISBN: 9781071614877
The rapid innate immune response to respiratory infection is essential to prevent the systemic dissemination of pathogens. This chapter outlines an experimental mouse model of respiratory infection by gram-negative Pseudomonas aeruginosa and analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b2018a3fafb42c219559f436558710
https://doi.org/10.1007/978-1-0716-1488-4_6
https://doi.org/10.1007/978-1-0716-1488-4_6
Publikováno v:
Drugs of Today. 58:335
Molnupiravir (MK-4482, EIDD-2801) is a promising broad-spectrum experimental antiviral developed by MerckCo. It is a nucleoside analogue prodrug that undergoes rapid conversion into nucleoside triphosphate (NTP) by intracellular metabolic processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa1305167453a8b023a38c5e1efcbf7
https://doi.org/10.1358/dot.2022.58.7.3419558
https://doi.org/10.1358/dot.2022.58.7.3419558
Autor:
Joshua Levitt, Aki Tanikawa, Takayuki Komatsu, Kelsey A. Smith, Muhammad Muzzammil Edhi, Satoru Yoshikawa, Suguru Koyama, Mai Michishita, Okishi Mashita, Catherine Roach, Brian W. LeBlanc, Carl Y. Saab
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
We present a multimodal method combining quantitative electroencephalography (EEG), behavior and pharmacology for pre-clinical screening of analgesic efficacy in vivo. The method consists of an objective and non-invasive approach for realtime assessm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faae52f5b4e6b2b0e10b889c2b8666aa
http://link.springer.com/article/10.1038/s41598-018-34594-2
http://link.springer.com/article/10.1038/s41598-018-34594-2
Publikováno v:
Brain Research Bulletin. 130:75-80
Recent studies in our laboratory showed that cortical theta oscillations correlate with pain in rodent models. In this study, we sought to validate our pre-clinical data using EEG recordings in humans during immersion of the hand in ice cold water, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27460150dd5c888e248b8c6d4712a78
https://doi.org/10.1016/j.brainresbull.2016.12.011
https://doi.org/10.1016/j.brainresbull.2016.12.011
Autor:
Angelo Mandarino, John J. Godleski, Loreilys Mejias Rivera, Hadley Witt, David Gregory, Brian W. LeBlanc, Alexey V. Fedulov, Connor C. McGuire
Publikováno v:
Environ Res
Talc and titanium dioxide are naturally occurring water-insoluble mined products usually available in the form of particulate matter. This study was prompted by epidemiological observations suggesting that perineal use of talc powder is associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ce5e446faa8cd5dbfcbb31e3e27b30
https://pubmed.ncbi.nlm.nih.gov/31785414
https://pubmed.ncbi.nlm.nih.gov/31785414