Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Brian W, Allwood"'
Autor:
Nicolas A. Menzies, Brian W. Allwood, Anna S. Dean, Pete J. Dodd, Rein M. G. J. Houben, Lyndon P. James, Gwenan M. Knight, Jamilah Meghji, Linh N. Nguyen, Andrea Rachow, Samuel G. Schumacher, Fuad Mirzayev, Ted Cohen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract In 2020, almost half a million individuals developed rifampicin-resistant tuberculosis (RR-TB). We estimated the global burden of RR-TB over the lifetime of affected individuals. We synthesized data on incidence, case detection, and treatmen
Externí odkaz:
https://doaj.org/article/67db4f0e99bd484ab56a1ea0cdfb46bf
Autor:
Jennifer K. van Heerden, Elizabeth H. Louw, Friedrich Thienemann, Mark E. Engel, Brian W. Allwood
Publikováno v:
European Respiratory Review, Vol 33, Iss 171 (2024)
Background: The prevalence of tuberculosis (TB)-associated pulmonary hypertension (PH) has not previously been quantified, resulting in an underappreciated burden of disease. We aimed to estimate the prevalence of PH in post-TB and active TB populati
Externí odkaz:
https://doaj.org/article/c30bb97f8b114e8a9a89ffbacf7a8c15
Autor:
Elsa du Bruyn, Cari Stek, Remi Daroowala, Qonita Said-Hartley, Marvin Hsiao, Georgia Schafer, Rene T. Goliath, Fatima Abrahams, Amanda Jackson, Sean Wasserman, Brian W. Allwood, Angharad G. Davis, Rachel P.-J. Lai, Anna K. Coussens, Katalin A. Wilkinson, Jantina de Vries, Nicki Tiffin, Maddalena Cerrone, Ntobeko A. B. Ntusi, HIATUS consortium, Catherine Riou, Robert J. Wilkinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Here the authors describe outcomes of SARS-CoV-2 infection in an African setting of high HIV-1 and tuberculosis prevalence. They find that tuberculosis is a common co-morbidity in patients admitted to hospital with COVID-19 and that the immune respon
Externí odkaz:
https://doaj.org/article/d34350d162f94a06b08193aa90938e4d
Autor:
Arifa Parker, Linda Boloko, Muhammad S. Moolla, Nabilah Ebrahim, Birhanu T. Ayele, Alistair G. B. Broadhurst, Boitumelo Mashigo, Gideon Titus, Timothy de Wet, Nicholas Boliter, Michael-Jon Rosslee, Nectarios Papavarnavas, Riezaah Abrahams, Marc Mendelson, Sipho Dlamini, Jantjie J. Taljaard, Hans W. Prozesky, Abdurasiet Mowlana, Abraham J. Viljoen, Neshaad Schrueder, Brian W. Allwood, Usha Lalla, Joel A. Dave, Greg Calligaro, Dion Levin, Deborah Maughan, Ntobeko A. B. Ntusi, Peter S. Nyasulu, Graeme Meintjes, Coenraad F. N. Koegelenberg, Ayanda T. Mnguni, Sean Wasserman
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background There is still a paucity of evidence on the outcomes of coronavirus disease 2019 (COVID-19) among people living with human immunodeficiency virus (PWH) and those co-infected with tuberculosis (TB), particularly in areas where thes
Externí odkaz:
https://doaj.org/article/232c699cb84945ff9fc52e88a03daf17
Autor:
Marwan Almubarek, Darryl P. Boy, Usha Lalla, Brian W. Allwood, Elvis M. Irusen, Coenraad F. N. Koegelenberg
Publikováno v:
Respirology Case Reports, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract A 65‐year‐old female was admitted with rapidly progressive respiratory failure requiring intubation and mechanical ventilation. She was considered to have an infective exacerbation of underlying interstitial lung disease (ILD). She impro
Externí odkaz:
https://doaj.org/article/a43a97d4f71445138c9c4e688eb49916
Autor:
Anneke C Hesseling, Alex Doruyter, Elizabeth Whittaker, James A Seddon, Brian W Allwood, Graeme Hoddinott, David A J Moore, Stephanus Malherbe, H Simon Schaaf, Gert Van Zyl, Marieke M van der Zalm, Jeremi Swanepoel, Klassina Zimri, Megan Palmer, Gezila De Beer, Leanie Kleynhans, Sarah M Johnson, Vita Jongen, Dillon Wademan, Khanyisa Mcimeli, Stephanie Jacobs, Ruan Swanepoel, Charlotte Heuvelings, Stephanie Griffith-Richards
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Introduction A considerable burden of the tuberculosis (TB) epidemic is found in adolescents. The reasons for increased susceptibility to TB infection and higher incidence of TB disease in adolescence, compared with the 5–10 years old age group, ar
Externí odkaz:
https://doaj.org/article/25e179c2055c41f89bb7b4eb98219aef
Autor:
Leigh Ann Kotze, Gian van der Spuy, Bryan Leonard, Adam Penn-Nicholson, Munyaradzi Musvosvi, Shirley McAnda, Stephanus T. Malherbe, Mzwandile Erasmus, Thomas Scriba, Coenraad F. N. Koegelenberg, Brian W. Allwood, Gerhard Walzl, Nelita du Plessis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Myeloid-derived suppressor cells (MDSC) have been identified in the peripheral blood and granulomas of patients with active TB disease, but their phenotype-, function-, and immunosuppressive mechanism- spectrum remains unclear. Importantly, the frequ
Externí odkaz:
https://doaj.org/article/e20a5a117b5e45b88563e406f947afea
Autor:
Peter S Nyasulu, Birhanu T Ayele, Coenraad F Koegelenberg, Elvis Irusen, Usha Lalla, Razeen Davids, Yazied Chothia, Francois Retief, Marianne Johnson, Stephen Venter, Renilda Pillay, Hans Prozesky, Jantjie Taljaard, Arifa Parker, Eric H Decloedt, Portia Jordan, Sa'ad Lahri, M Rafique Moosa, Muhammad Saadiq Moolla, Anteneh Yalew, Nicola Baines, Padi Maud, Elizabeth Louw, Andre Nortje, Rory Dunbar, Lovemore N Sigwadhi, Veranyuy D Ngah, Jacques L Tamuzi, Annalise Zemlin, Zivanai Chapanduka, René English, Brian W Allwood
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279565 (2022)
BackgroundOver 130 million people have been diagnosed with Coronavirus disease 2019 (COVID-19), and more than one million fatalities have been reported worldwide. South Africa is unique in having a quadruple disease burden of type 2 diabetes, hyperte
Externí odkaz:
https://doaj.org/article/177aaa47a0a4477bbc01ba1094211319
Autor:
Nicolas A Menzies, PhD, Matthew Quaife, PhD, Brian W Allwood, PhD, Anthony L Byrne, PhD, Anna K Coussens, PhD, Anthony D Harries, ProfMD, Florian M Marx, PhD, Jamilah Meghji, PhD, Debora Pedrazzoli, PhD, Joshua A Salomon, ProfPhD, Sedona Sweeney, PhD, Sanne C van Kampen, PhD, Robert S Wallis, ProfMD, Rein M G J Houben, PhD, Ted Cohen, ProfDPH
Publikováno v:
The Lancet Global Health, Vol 9, Iss 12, Pp e1679-e1687 (2021)
Summary: Background: Many individuals who survive tuberculosis disease face ongoing disability and elevated mortality risks. However, the impact of post-tuberculosis sequelae is generally omitted from policy analyses and disease burden estimates. We
Externí odkaz:
https://doaj.org/article/21d914f0666c40ee84545434ff596058
Autor:
Leigh A. Kotze, Caroline G. G. Beltran, Dirk Lang, Andre G. Loxton, Susan Cooper, Maynard Meiring, Coenraad F. N. Koegelenberg, Brian W. Allwood, Stephanus T. Malherbe, Andriette M. Hiemstra, Brigitte Glanzmann, Craig Kinnear, Gerhard Walzl, Nelita du Plessis
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
TB is a highly infectious disease, with granulomas as its hallmark. Granulomas play an important role in the control of M. tuberculosis
Externí odkaz:
https://doaj.org/article/b3f1a5f1eb7747178c7f7312ef5a5750