Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brian Volk"'
Publikováno v:
Volume 4B: Combustion, Fuels, and Emissions.
It is a common practice to relate emissions performance of Dry Low Emissions (DLE) combustion systems to the flame temperature that is estimated from the mass flows of air and fuel flowing through the premixer. In many combustion systems, the exit te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95260672409e8febb9d39e059450846e
https://doi.org/10.1115/gt2020-15304
https://doi.org/10.1115/gt2020-15304
A new obligate CXCL4–CXCL12 heterodimer for studying chemokine heterodimer activities and mechanisms
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Chemokines form a family of proteins with critical roles in many biological processes in health and disease conditions, including cardiovascular, autoimmune diseases, infections, and cancer. Many chemokines engage in heterophilic interaction
Externí odkaz:
https://doaj.org/article/9bb4e90827cd4751a21b770fa49bc1a5
Autor:
Brian Volk, Radoslaw Laufer, Andrew P. Crew, Mridula Kadalbajoo, Paula A. Tavares-Greco, Mark J. Mulvihill, Hanqing Dong, Douglas S. Werner
Publikováno v:
Tetrahedron Letters. 51:3899-3901
The preparation of 5,7-disubstituted imidazo[5,1-f][1,2,4]triazin-4-amines, exemplified by 5-[3-(benzyloxy)phenyl]-7-cyclobutylimidazo[5,1-f][1,2,4]triazin-4-amine, was developed through a linear and three convergent synthetic strategies, with the la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::311c81c2caf33edd385d0de83f43aaf3
https://doi.org/10.1016/j.tetlet.2010.05.083
https://doi.org/10.1016/j.tetlet.2010.05.083
Autor:
Andrew P. Crew, Robert A. Wild, Mark Bittner, Andrew Cooke, Meizhong Jin, Shripad V. Bhagwat, Hanqing Dong, Douglas S. Werner, Xin Chen, Christine Mantis, Jonathan A. Pachter, Jennifer Kahler, Neil W. Gibson, Prafulla C. Gokhale, Lee D. Arnold, Heather Coate, Jing Wang, Brian Volk, Ayako Honda, Mark J. Mulvihill, Anna Chan, Paula A. Tavares-Greco
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(7)
The discovery and optimization of a series of imidazo[1,5-a]pyrazine inhibitors of mTOR is described. HTS hits were optimized for potency, selectivity and metabolic stability to provide the orally bioavailable proof of concept compound 4c that demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3d9f82c18f30d1e909a368b2bbd844
https://pubmed.ncbi.nlm.nih.gov/21353551
https://pubmed.ncbi.nlm.nih.gov/21353551
Autor:
Brian Volk, Bijoy Panicker, Qinghua Weng, Meizhong Jin, Andrew P. Crew, Hanqing Dong, Xin Chen, Kathryn M. Stolz, Doug Werner, Kam W. Siu, Paula A. R. Tavares, Arno G. Steinig, Lifu Ma, Mark J. Mulvihill, Eilaf Ahmed, Matthew Cox, An-Hu Li
Publikováno v:
Organicbiomolecular chemistry. 5(1)
A highly effective one-pot Friedlander quinoline synthesis using inexpensive reagents has been developed. o-Nitroarylcarbaldehydes were reduced to o-aminoarylcarbaldehydes with iron in the presence of catalytic HCl (aq.) and subsequently condensed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9847573610e389b608711996001fc0ae
https://pubmed.ncbi.nlm.nih.gov/17164907
https://pubmed.ncbi.nlm.nih.gov/17164907
Autor:
Qinghua Weng, Andrew P. Crew, Kathryn M. Stolz, Izabela Sujka, Qun-Sheng Ji, Lydia Saroglou, Robin Wilkes, Patricia Beck, Cara Cesario, Andrew Cooke, Mark J. Mulvihill, K.W. Foreman, Brian Volk, Anthony Nigro, Matthew Cox, Gilda Mak, Doug Werner, Matthew O'Connor, Hanqing Dong, Lixin Feng
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(4)
A series of novel 8-amino-1,3-disubstituted-imidazo[1,5-a]pyrazines was designed and synthesized as IGF-IR inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029cf74ac11b81e0a031f3b2ae2e79cb
https://pubmed.ncbi.nlm.nih.gov/17127062
https://pubmed.ncbi.nlm.nih.gov/17127062
Publikováno v:
Applied optics. 36(20)
An optical design comparison is made between two 60 degrees field-of-view long-eye-relief eyepieces used for viewing a flat image-intensifier P-43 phosphor screen output. One eyepiece contains both spherical glass elements and plastic aspheric elemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2917b142e551af4ff3ac39750f334947
https://pubmed.ncbi.nlm.nih.gov/18259275
https://pubmed.ncbi.nlm.nih.gov/18259275
Publikováno v:
Diffractive Optics and Micro-Optics.
Eyepiece optical designs were developed for a wide angle eyepiece with a large exit pupil and eye relief. In addition to the design criteria listed below in Table 1, one design was of a conventional configuration (aspherics and plastics permitted) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c37e1483830c7e2fb2547ddd87b5191
https://doi.org/10.1364/domo.1996.dtua.5
https://doi.org/10.1364/domo.1996.dtua.5