Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Brian T. Luk"'
Autor:
Baharak Bahmani, Hua Gong, Brian T. Luk, Kristofer J. Haushalter, Ethel DeTeresa, Mark Previti, Jiarong Zhou, Weiwei Gao, Jack D. Bui, Liangfang Zhang, Ronnie H. Fang, Jie Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The immunostimulatory properties of TLR7/8 agonists, such as resiquimod, have been exploited for cancer immunotherapy. Here, the authors design platelet membrane-cloaked nanoparticles for selective intratumoral delivery of resiquimod, resulting in po
Externí odkaz:
https://doaj.org/article/70f51776b4444f01b293b1d2b1518bff
Autor:
Austin L. LaGrow, Phillip S. Coburn, Frederick C. Miller, Craig Land, Salai Madhumathi Parkunan, Brian T. Luk, Weiwei Gao, Liangfang Zhang, Michelle C. Callegan
Publikováno v:
mSphere, Vol 2, Iss 6 (2017)
ABSTRACT Intraocular infections are a potentially blinding complication of common ocular surgeries and traumatic eye injuries. Bacterial toxins synthesized in the eye can damage intraocular tissue, often resulting in poor visual outcomes. Enteroccocu
Externí odkaz:
https://doaj.org/article/82aadfce2f2a47458f3780d1003dfb2b
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Group A Streptococcus (GAS), an important human-specific Gram-positive bacterial pathogen, is associated with a broad spectrum of disease, ranging from mild superficial infections such as pharyngitis and impetigo, to serious invasive infections inclu
Externí odkaz:
https://doaj.org/article/33d28e744de442139d81f5fc8789011c
Publikováno v:
Theranostics, Vol 2, Iss 12, Pp 1117-1126 (2012)
The relatively new field of nanotheranostics combines the advantages of in vivo diagnosis with the ability to administer treatment through a single nano-sized carrier, offering new opportunities for cancer diagnosis and therapy. Nanotheranostics has
Externí odkaz:
https://doaj.org/article/ad333d6d8fcd42b4a6b2940b560cdd0a
Autor:
Hua Gong, Weiwei Gao, Liangfang Zhang, Mark Previti, Ethel DeTeresa, Jie Zhang, Ronnie H. Fang, Brian T. Luk, Kristofer J. Haushalter, Jiarong Zhou, Baharak Bahmani, Jack D. Bui
Publikováno v:
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Intratumoral immunotherapy is an emerging modality for the treatment of solid tumors. Toll-like receptor (TLR) agonists have shown promise for eliciting immune responses, but systemic administration often results in the development of adverse side ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0db4db29ccae02a9cdf386542bf5fd
http://europepmc.org/articles/PMC8012593
http://europepmc.org/articles/PMC8012593
Publikováno v:
Autophagy. 14:1359-1375
Although antiretroviral therapy is highly effective in suppressing human immunodeficiency virus type-1 (HIV) replication, treatment has failed to eliminate viral reservoirs and discontinuation of treatment results in viral reactivation. Here, we demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb211618be66fd86f8452bc23a9bef8
https://doi.org/10.1080/15548627.2018.1476014
https://doi.org/10.1080/15548627.2018.1476014
Autor:
Joshua Olson, Tamara Escajadillo, Brian T. Luk, Weiwei Gao, Victor Nizet, Ronnie H. Fang, Sophia Zhang, Soracha Thamphiwatana, Liangfang Zhang, Pavimol Angsantikul, Qiangzhe Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 43
Sepsis, resulting from uncontrolled inflammatory responses to bacterial infections, continues to cause high morbidity and mortality worldwide. Currently, effective sepsis treatments are lacking in the clinic, and care remains primarily supportive. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ee067f50ebcdc4d21f0002c9c01582
https://doi.org/10.1073/pnas.1714267114
https://doi.org/10.1073/pnas.1714267114
Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides
Autor:
Gang Zhang, Liangfang Zhang, Grant R. Campbell, Xiaoli Wei, Brian T. Luk, Ronnie H. Fang, Stephen A. Spector
Publikováno v:
Cell death & disease, vol 10, iss 6
Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
Despite significant advances in the treatment of human immunodeficiency virus type-1 (HIV) infection, antiretroviral therapy only suppresses viral replication but is unable to eliminate infection. Thus, discontinuation of antiretrovirals results in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a1a1bbedc175d67617d09cdc18cf97
https://escholarship.org/uc/item/9s3213w2
https://escholarship.org/uc/item/9s3213w2
Autor:
Gang, Zhang, Brian T, Luk, Xiaoli, Wei, Grant R, Campbell, Ronnie H, Fang, Liangfang, Zhang, Stephen A, Spector
Publikováno v:
Cell Death & Disease
Despite significant advances in the treatment of human immunodeficiency virus type-1 (HIV) infection, antiretroviral therapy only suppresses viral replication but is unable to eliminate infection. Thus, discontinuation of antiretrovirals results in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed1e4b063e42259b339dc1d30de379d0
https://pubmed.ncbi.nlm.nih.gov/31142734
https://pubmed.ncbi.nlm.nih.gov/31142734
Autor:
Diana Dehaini, Fei Wang, Zhiqing Pang, Che Ming Jack Hu, Weiyue Lu, Pavimol Angsantikul, Liangfang Zhang, Weiwei Gao, Ronnie H. Fang, Brian T. Luk, Ashley V. Kroll, Soracha Thamphiwatana
Publikováno v:
Advanced Functional Materials. 26:1628-1635
With the rising threat of antibiotic-resistant bacteria, vaccination is becoming an increasingly important strategy to prevent and manage bacterial infections. Made from deactivated bacterial toxins, toxoid vaccines are widely used in the clinic as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18d99e19cab0e317221e71b6f5d45795
https://doi.org/10.1002/adfm.201505231
https://doi.org/10.1002/adfm.201505231