Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Brian T. Bloomquist"'
Autor:
H. Mark Skolnick, D. Ted Adams, Thanh Tran, Srikanth Jammulapati, Charles H. Hensel, Brian T. Bloomquist, Steven C. Hunt, Richard E. Gress, Robyn Riley, Drew Gibbs, Chris Neff, Victor Abkevich, Alexander Gutin, Donna Shattuck, Jennifer Potter, Deanna L. Russell, M.M. Peter Rae, David Sexton, Steven Stone, Georges C. Frech, Diana Iliev, John Amatruda
Publikováno v:
The American Journal of Human Genetics. 70:1459-1468
Although the predisposition to morbid obesity is heritable, the identities of the disease-causing genes are largely unknown. Therefore, we have conducted a genomewide search with 628 markers, using multigenerational Utah pedigrees to identify genes i
Autor:
Brian T. Bloomquist, Ann R. Gore-Willse, Su-Ellen Brown, Leonid Zhelnin, Paul Gregor, Linda J. Cornfield, Michelle R. Beauchamp
Publikováno v:
Biochemical and Biophysical Research Communications. 243:474-479
Galanin is a peptide hormone which modulates a wide variety of physiological processes, including secretion, muscle contraction, cognitive function, the reproductive axis, and feeding. Two galanin receptor subtypes, GalR1 and GalR2, have been cloned;
Autor:
Brian T. Bloomquist, Lore Lewis-Higgins, Nelson Velazquez, Linda J. Cornfield, Peiling Jiang, Yinghe Hu, Michael L. McCaleb, Lizbeth Friedman, Jaime R. Flores-Riveros, Lynn B. DeCarr, Jean Schaefer, Yola Sadlowski
Publikováno v:
Journal of Biological Chemistry. 271:26315-26319
Neuropeptide Y (NPY) plays important roles in the central control of appetite and energy balance, but the receptor subtype responsible for this function has not been cloned. Here we report the cloning by expression of a novel NPY receptor subtype fro
Publikováno v:
Endocrinology. 135:2714-2722
Regulated endocrine-specific protein-18 (RESP18) is an 18-kilodalton endocrine-specific transcript whose expression is regulated by a number of different physiological and pharmacological stimuli in different tissues. RESP18 messenger RNA was identif
Publikováno v:
Endocrinology. 135:1178-1185
Low stringency screening of a rat hypothalamic complementary DNA library for additional members of the subtilisin-like prohormone convertase (PC) family identified rat PACE4, which is 90% identical to human PACE4 in amino acid sequence, with much low
Publikováno v:
Journal of Biological Chemistry. 269:9113-9122
The homogeneous nature of the rat intermediate pituitary makes it a powerful model system in which to study peptide hormone secretion. Adult male rats were treated with bromocriptine, a dopamine agonist, or haloperidol, a dopamine antagonist, for 3 w
Publikováno v:
Annals of the New York Academy of Sciences. 680:147-160
Studies on the mRNAs encoding PAM and on the various PAM proteins have begun to reveal some of the intricate mechanisms used to optimize the ability of this enzyme to carry out the alpha-amidation of peptides. Comparison of the regulatory elements go
Autor:
Richard E. Mains, Brian T. Bloomquist
Publikováno v:
Cellular Physiology and Biochemistry. 3:197-212
The control of gene expression is critical to the proper development of all organisms. Genetic control at the posttranslational level is an important system of such regulation. Recent developments in
Publikováno v:
Journal of Biological Chemistry. 268:1763-1769
Two subtilisin-like endoproteases called PC1 and PC2 are distributed in a tissue-specific manner in the pituitary and in the brain. AtT-20 cells and corticotropes of the anterior pituitary express primarily PC1 and perform a limited number of cleavag
Publikováno v:
DNA and Cell Biology. 11:791-797
A method is described for quickly and reproducibly isolating genomic DNA contiguous with known DNA sequence by means of the polymerase chain reaction (PCR). Flanking genomic DNA is isolated using a biotinylated sequence-specific primer in combination