Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Brian T, David"'
Publikováno v:
PAIN Reports, Vol 9, Iss 6, p e1184 (2024)
Abstract. Introduction:. Central neuropathic pain (CNP) commonly develops in patients after spinal cord injury (SCI), causing debilitating symptoms and sensory abnormalities to mechanical and thermal stimuli. The biological variability of pain phenot
Externí odkaz:
https://doaj.org/article/db041e98abcd4e36bc968a6fc41f77ca
Autor:
Usha Nekanti, Pooja S. Sakthivel, Atena Zahedi, Dana A. Creasman, Rebecca A. Nishi, Courtney M. Dumont, Katja M. Piltti, Glenn L. Guardamondo, Norbert Hernandez, Xingyuan Chen, Hui Song, Xiaoxiao Lin, Joshua Martinez, Lillian On, Anita Lakatos, Kiran Pawar, Brian T. David, Zhiling Guo, Stephanie K. Seidlits, Xiangmin Xu, Lonnie D. Shea, Brian J. Cummings, Aileen J. Anderson
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-20 (2024)
Abstract Regeneration in the injured spinal cord is limited by physical and chemical barriers. Acute implantation of a multichannel poly(lactide-co-glycolide) (PLG) bridge mechanically stabilizes the injury, modulates inflammation, and provides a per
Externí odkaz:
https://doaj.org/article/a83ff1b397fa4089b91e5e42b4e4bde0
Publikováno v:
Journal of Neurotrauma. 40:793-806
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Spinal cord injury (SCI) is a devastating neurological disorder that damages motor, sensory, and autonomic pathways. Recent advances in stem cell therapy have allowed for the in vitro generation of motor neurons (MNs) showing electrophysiological and
Externí odkaz:
https://doaj.org/article/a03ee119ed58489189627d32a6c5aee3
Spinal cord injury (SCI)-induced tissue damage spreads to neighboring spared cells in the hours, days and weeks following injury leading to exacerbation of tissue damage and functional deficits. Among the biochemical changes is the rapid reduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7cf07d29e1c7e0a05482fe9f56374c
https://doi.org/10.1101/2023.01.17.524307
https://doi.org/10.1101/2023.01.17.524307
Publikováno v:
Medicines, Vol 7, Iss 5, p 27 (2020)
Background: Although many therapeutic approaches have been attempted to treat spinal cord injury, cellular transplantation offers the greatest promise in reconstituting the architecture of the damaged cord. Methods: A literature review was conducted
Externí odkaz:
https://doaj.org/article/9b842bb221b54ad8825c4d047f97ccdd
Publikováno v:
Journal of neurotrauma.
Spinal cord injury (SCI) affects approximately 1.3 million people living in the United States. Most research efforts have been focused on reversing paralysis, as this is arguably the most defining feature of SCI. The damage due to SCI, however, exten
Autor:
Brian T. David, Jessica J. Curtin, Jennifer L. Brown, Kerri Scorpio, Veena Kandaswamy, David J. C. Coutts, Ana Vivinetto, Paola Bianchimano, Saravanan S. Karuppagounder, Mariajose Metcalfe, John W. Cave, Caitlin E. Hill
Publikováno v:
GliaREFERENCES.
Hypoxic preconditioning is protective in multiple models of injury and disease, but whether it is beneficial for cells transplanted into sites of spinal cord injury (SCI) is largely unexplored. In this study, we analyzed whether hypoxia-related preco
Autor:
Josha Woodward, John Paul G. Kolcun, Hani R. Malone, Richard G. Fessler, Mena G. Kerolus, Christopher D. Witiw, Shahjehan Ahmad, R David Fessler, Lacin Koro, Kevin C. Keegan, Brian T. David
Publikováno v:
Journal of Neurosurgery: Spine. :1-7
OBJECTIVE The goal of this study was to evaluate the clinical and radiographic outcomes of a novel multidirectional in situ expandable minimally invasive surgery (MIS) transforaminal lumbar interbody fusion (TLIF) cage. METHODS A retrospective analys
Autor:
John E. O'Toole, Richard G. Fessler, Kevin C. Keegan, Ziev B. Moses, Sharmeen Razvi, Harel Deutsch, Brian T. David, Ricardo B. V. Fontes, Fadi Hamati, Seok Yoon Oh, Andrew Platt, Christopher D. Witiw
Publikováno v:
J Spine Surg
BACKGROUND: Single-level lumbar degenerative disc disease (DDD) remains a significant cause of morbidity in adulthood. Anterior lumbar interbody fusion (ALIF) and Transforaminal lumbar interbody fusion (TLIF) are surgical techniques developed to trea