Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations

Autor: Alexandra C. Willcox, Jack D. Griffith, Shuai Jiang, Altaf H. Sarker, Priscilla K. Cooper, Albino Bacolla, Clifford Ng, Mai Zong Her, John A. Tainer, Daniel J. Rosenberg, Aye C. Thwin, Andrew S. Arvai, Miaw Sheue Tsai, Michal Hammel, Kelly S. Trego, Alan G. Raetz, Brian Shih, Susan E. Tsutakawa, David S. Shin

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance DNA repair is essential to life and to avoidance of genome instability and cancer. Xeroderma pigmentosum group G (XPG) protein acts in multiple DNA repair pathways, both as an active enzyme and as a scaffold for coordinating with other r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d593687d33295b79020224b75f084ffa
https://doi.org/10.1073/pnas.1921311117

Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability

Autor: Jan H.J. Hoeijmakers, Priscilla K. Cooper, Brian Shih, Ann C. Parplys, Miaw Sheue Tsai, Torsten Groesser, Kelly S. Trego, Janice M. Pluth, Ayesu Hlaing, Michael R. Nelson, Weixing Zhao, Patrick Sung, Claudia Wiese, Albert R. Davalos, Björn Rydberg, Judith Campisi

Publikováno v: Trego, K S, Groesser, T, Davalos, A R, Parplys, A C, Zhao, W, Nelson, M R, Hlaing, A, Shih, B, Rydberg, B, Pluth, J M, Tsai, M-S, Hoeijmakers, J H J, Sung, P, Wiese, C, Campisi, J & Cooper, P K 2016, ' Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability ', Molecular Cell, vol. 61, pp. 535–546 . https://doi.org/10.1016/j.molcel.2015.12.026
Molecular cell, vol 61, iss 4
Trego, KS; Groesser, T; Davalos, AR; Parplys, AC; Zhao, W; Nelson, MR; et al.(2016). Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability. Molecular Cell, 61(4), 535-546. doi: 10.1016/j.molcel.2015.12.026. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2618t9h0
Molecular Cell, 61(4), 535-546. Cell Press

© 2016 Elsevier Inc. XPG is a structure-specific endonuclease required for nucleotide excision repair, and incision-defective XPG mutations cause the skin cancer-prone syndrome xeroderma pigmentosum. Truncating mutations instead cause the neurodevel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcfec2d212a7de1b61ea0d9e00e48d8
https://doi.org/10.1016/j.molcel.2015.12.026

P158: Vascular Compromise in Deep Neck Space Infections

Autor: Benjamin D. Webb, Kevin D. Pereira, Brian Shih-Ning Wang

Publikováno v: Otolaryngology–Head and Neck Surgery. 135

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ad08ddf337d42a52c0cb905c102dd76
https://doi.org/10.1016/j.otohns.2006.06.1192

Impalement injuries of the pediatric craniofacial skeleton with retained foreign bodies

Autor: Kevin D. Pereira, Benjamin D. Webb, Brian Shih-Ning Wang

Publikováno v: Archives of otolaryngology--headneck surgery. 131(2)

Penetrating trauma to the pediatric craniofacial skeleton, though uncommon, often presents a diagnostic and management dilemma in emergency departments and trauma centers because of the variety and complexity of potential injuries, some of which can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f6091f2941a320b54efd44e645b280
https://pubmed.ncbi.nlm.nih.gov/15723949

Invasive Fungal Rhinosinusitis at a Tertiary Care Cancer Center

Autor: Brian Shih-Ning Wang, Hend Hanna, Ehab Y. Hanna, Ray Y Hachem, Issam I Raad, Maha Boktour

Publikováno v: Otolaryngology - Head and Neck Surgery. 133:P173-P173

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0504557fe0d9edea05c9f27b406222d0
https://doi.org/10.1016/j.otohns.2005.05.393