Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Brian Seed"'
Autor:
Sandip Datta, Brian Seed
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191152 (2018)
Experimental data indicate that stochastic effects exerted at the level of translation contribute substantially to the variation in abundance of proteins expressed at moderate to high levels. This study analyzes the theoretical consequences of fluctu
Externí odkaz:
https://doaj.org/article/ce28d891fdd6403385babbb607960090
GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses.
Autor:
Danfeng Dong, Haisheng Zhou, Soon-Young Na, Rasma Niedra, Yibing Peng, Huajun Wang, Brian Seed, Guo Ling Zhou
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205303 (2018)
Higher vertebrates have evolved innate and adaptive immune systems to defend against foreign substances and pathogens. Sophisticated regulatory circuits are needed to avoid inappropriate immune responses and inflammation. GPR108 is a seven-transmembr
Externí odkaz:
https://doaj.org/article/0c92ee2a9aa04a3eaf9bcab58bfcd8af
Autor:
Michael L. Fitzgerald, Ramnik Xavier, Kathleen J. Haley, Ruth Welti, Julie L. Goss, Cari E. Brown, Debbie Z. Zhuang, Susan A. Bell, Naifang Lu, Mary Mckee, Brian Seed, Mason W. Freeman
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 621-632 (2007)
The highly branched mammalian lung relies on surfactant, a mixture of phospholipids, cholesterol, and hydrophobic proteins, to reduce intraalveolar surface tension and prevent lung collapse. Human mutations in the ABCA3 transporter have been associat
Externí odkaz:
https://doaj.org/article/ff30baedb58c4507ad5fe288a371c737
Autor:
Guo Ling Zhou, Arkadi Beloiartsev, Binglan Yu, David M Baron, Weihua Zhou, Rasma Niedra, Naifang Lu, Laurel T Tainsh, Warren M Zapol, Brian Seed, Kenneth D Bloch
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003950 (2013)
Epoxyeicosatrienoic acids (EETs) confer vasoactive and cardioprotective functions. Genetic analysis of the contributions of these short-lived mediators to pathophysiology has been confounded to date by the allelic expansion in rodents of the portion
Externí odkaz:
https://doaj.org/article/8dc92b3772fe40a68d870e96ab003376
Autor:
Sabine Lindquist, Diana Karitkina, Kristina Langnaese, Anita Posevitz-Fejfar, Burkhart Schraven, Ramnik Xavier, Brian Seed, Jonathan A Lindquist
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23978 (2011)
Src family kinases (SFK) control multiple processes during brain development and function. We show here that the phosphoprotein associated with glycosphigolipid-enriched microdomains (PAG)/Csk binding protein (Cbp) modulates SFK activity in the brain
Externí odkaz:
https://doaj.org/article/a4d5872ed6ca481f9709e7029a09a720
Autor:
Rakesh K. Jain, Brian Seed, Peigen Huang, Edward B. Brown, Michael F. Booth, Lance L. Munn, Dai Fukumura, Dan G. Duda
Supplementary Movie 1 from Differential Transplantability of Tumor-Associated Stromal Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201660f262ff4ef69fcb6d025b5c1189
https://doi.org/10.1158/0008-5472.22363308.v1
https://doi.org/10.1158/0008-5472.22363308.v1
Autor:
Rakesh K. Jain, Brian Seed, Peigen Huang, Edward B. Brown, Michael F. Booth, Lance L. Munn, Dai Fukumura, Dan G. Duda
Supplementary Movie 2 from Differential Transplantability of Tumor-Associated Stromal Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4085ac2608470ba34aa28aa4d2c4895e
https://doi.org/10.1158/0008-5472.22363305
https://doi.org/10.1158/0008-5472.22363305
Autor:
Rakesh K. Jain, Brian Seed, Peigen Huang, Edward B. Brown, Michael F. Booth, Lance L. Munn, Dai Fukumura, Dan G. Duda
At the time of transplantation, tumor fragments contain “passenger” cells: endothelial cells and other stromal cells from the original host. Here, we investigated the fate of genetically labeled endothelial and nonendothelial stromal cells after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa55b2aa986a51aac558511d0dfa6d1
https://doi.org/10.1158/0008-5472.c.6493647.v1
https://doi.org/10.1158/0008-5472.c.6493647.v1
Autor:
Bobby J. Cherayil, Chithirachelvi Vasudevan, Vladimir Yeliseyev, Nitya Jain, Stefan Halvorsen, Samira Ibrahim, Shaniah Prosper, Slim Sassi, Smriti Verma, Maria Ennamorati, Kara Clerkin, Joseph A. Gardecki, Brian Seed, Lynn Bry, Caryn Porter, Margot Kim, Guillermo J. Tearney
Publikováno v:
Proc Natl Acad Sci U S A
The thymus generates cells of the T cell lineage that seed the lymphatic and blood systems. Transcription factor regulatory networks control the lineage programming and maturation of thymic precursor cells. Whether extrathymic antigenic events, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c17f9b804f569aabcfbb0c222c16c46
https://doi.org/10.1073/pnas.1915047117
https://doi.org/10.1073/pnas.1915047117
Autor:
André Veillette, Dominique Davidson, Hua Gu, Xin Li, Ming-Chao Zhong, Silvia Bolland, Pier Paolo Pandolfi, Ramnik J. Xavier, Brian Seed
Publikováno v:
Elsevier
Summary - The transmembrane adaptor PAG (Cbp) has been proposed to mediate membrane recruitment of Csk, a cytoplasmic protein tyrosine kinase playing a critical inhibitory role during T cell activation, by inactivating membrane-associated Src kinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea246452e79ca69b3950e0f5634d6ade