Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Brian Salmons"'
Autor:
Brian Salmons, Walter H. Gunzburg
Publikováno v:
Life, Vol 13, Iss 12, p 2357 (2023)
Background: The use of encapsulated cells for the in vivo delivery of biotherapeutics is a promising new technology to potentiate the effectiveness of cell-based therapies for veterinary and human application. One use of the technology is to locally
Externí odkaz:
https://doaj.org/article/7935943e52b54f96a4e1d082563c468e
Autor:
Walter H. Gunzburg, Myo Myint Aung, Pauline Toa, Shirelle Ng, Eliot Read, Wee Jin Tan, Eva Maria Brandtner, John Dangerfield, Brian Salmons
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-14 (2020)
Abstract Background Gut microbiota in humans and animals play an important role in health, aiding in digestion, regulation of the immune system and protection against pathogens. Changes or imbalances in the gut microbiota (dysbiosis) have been linked
Externí odkaz:
https://doaj.org/article/6cf71bd6e4b24965af1c618dde1f7618
Autor:
Walter H. Gunzburg, Brian Salmons
Publikováno v:
Viruses, Vol 14, Iss 11, p 2342 (2022)
Most of the evidence that a human betaretrovirus (HBRV/HMTV) highly related to mouse mammary tumour virus (MMTV) has an etiological role in breast cancer has been summarized in a recent comprehensive Special Issue of “Viruses” entitled “Human B
Externí odkaz:
https://doaj.org/article/8a8e820c2bb24ebebed3b2c4962a275e
Autor:
Gabriela Zavala, María-Paz Ramos, Aliosha I. Figueroa-Valdés, Pablo Cisternas, Ursula Wyneken, Macarena Hernández, Pauline Toa, Brian Salmons, John Dangerfield, Walter H. Gunzburg, Maroun Khoury
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their secretome. This paracrine effect is mediated by secreted growth factors and extracellular v
Externí odkaz:
https://doaj.org/article/a8bac53d341549bd929258b00f83f395
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
BackgroundAlthough the risk factors for breast cancer are well established, namely female gender, early menarche and late menopause plus the protective influence of early pregnancy, the underlying causes of breast cancer remain unknown. The developme
Externí odkaz:
https://doaj.org/article/5670f5cf730d46948b014ff6cae87ac6
Autor:
J. Matthias Löhr, Stephan L. Haas, Jens C. Kröger, Helmut M. Friess, Raimund Höft, Peter E. Goretzki, Christian Peschel, Markus Schweigert, Brian Salmons, Walter H. Gunzburg
Publikováno v:
Pharmaceutics, Vol 6, Iss 3, Pp 447-466 (2014)
Despite progress in the treatment of pancreatic cancer, there is still a need for improved therapies. In this manuscript, we report clinical experience with a new therapy for the treatment of pancreatic cancer involving the implantation of encapsulat
Externí odkaz:
https://doaj.org/article/434329c2a44c4e2799229a8dc22d2f9b
Autor:
Monika Michałowska, Stanislaw Winiarczyk, Łukasz Adaszek, Wojciech Łopuszyński, Zbigniew Grądzki, Brian Salmons, Walter H Günzburg
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102061 (2014)
Based upon promising preclinical studies, a clinical trial was performed in which encapsulated cells overexpressing cytochrome P450 enzyme isoform 2B1 were implanted around malignant mammary tumours arising spontaneously in dogs. The dogs were then g
Externí odkaz:
https://doaj.org/article/4b821ea2311f40ed8bb05cb522000c32
Autor:
Juraj Hlavaty, Helga Petznek, Harry Holzmüller, Angelika Url, Gerrit Jandl, André Berger, Brian Salmons, Walter H Günzburg, Matthias Renner
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40611 (2012)
BACKGROUND: Gene-directed enzyme prodrug therapy (GDEPT) is a two-step treatment protocol for solid tumors that involves the transfer of a gene encoding a prodrug-activating enzyme followed by administration of the inactive prodrug that is subsequent
Externí odkaz:
https://doaj.org/article/e95c2c5e237c44b4b28b111708b35556
Publikováno v:
Cell Transplantation, Vol 18 (2009)
Cell transplantation after enclosing in microcapsules has been studied as an alternative approach for treatment of wide variety of diseases. In the present study, we examined the feasibility of using agarose microcapsules, having a cell-enclosing hol
Externí odkaz:
https://doaj.org/article/61fcbc64520641a1b93f835692e3d8c0
Autor:
Noel J. Whitaker, Louise Lutze-Mann, Warick Delprado, William D. Rawlinson, Harpreet Johal, Patrick Moody, Benjamin Heng, Yulan Ye, Brian Salmons, Wendy K. Glenn, James S. Lawson
Mouse mammary tumor virus (MMTV) sequences have been reported to be present in some human breast cancers, but it is unclear whether they have any causal role. In mice, MMTV promotes tumor formation indirectly by insertional mutagenesis of Wnt oncogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a10e9de369db63b9026ea1b90b7d60a
https://doi.org/10.1158/0008-5472.c.6501581.v1
https://doi.org/10.1158/0008-5472.c.6501581.v1
