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pro vyhledávání: '"Brian S. Sohn"'
Autor:
Matthew K. Howard, Karlie R. Miller, Brian S. Sohn, Jeremy J. Ryan, Andy Xu, Meredith E. Jackrel
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Phenol-soluble modulins (PSMs) are the primary proteinaceous component of Staphylococcus aureus biofilms. Residence in the protective environment of biofilms allows bacteria to rapidly evolve and acquire antimicrobial resistance, which can l
Externí odkaz:
https://doaj.org/article/61adf2fa236b4edabda0ec692c3ce899
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103900- (2022)
Summary: Matrin-3 (MATR3) is a DNA- and RNA-binding protein implicated in amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and distal myopathy. Here, we report the development of a yeast model of MATR3 proteotoxicity and aggregatio
Externí odkaz:
https://doaj.org/article/e3d0707b0cd24cf28239b5605c33ad43
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230198 (2020)
Hsp104 is a hexameric AAA+ yeast disaggregase capable of solubilizing disordered aggregates and amyloid. Hsp104 couples ATP hydrolysis to polypeptide translocation through its central channel. Substrate binding by Hsp104 is mediated primarily by two
Externí odkaz:
https://doaj.org/article/bd0e173ea6014261a77f73e4966b670a