Impact of molecular subtype and race on HR+, HER2− breast cancer survival

Autor: Ann Tezak, Tuya Pal, Yuwei Zhu, Wei Zheng, Anne Weidner, Jaleesa Moore, Xiao-Ou Shu, Ingrid A. Mayer, Sonya Reid, Xuefeng Wang, Sydney Cadiz, Diane N. Haddad, Brian S. Mautz

Publikováno v: Breast Cancer Res Treat

PURPOSE: There is an urgent need to understand the biological factors contributing to the racial survival disparity among women with hormone receptor-positive (HR+), HER2− breast cancer. In this study, we examined the impact of PAM50 subtype on 10-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04368a6a5fd88c544709ea900a0ac48b
https://doi.org/10.1007/s10549-021-06342-0

Development time mediates the effect of larval diet on ageing and mating success of male antler flies in the wild

Autor: Christopher S. Angell, Russell Bonduriansky, Howard D. Rundle, Nicolas O. Rode, Mathieu J. Oudin, Brian S. Mautz

Publikováno v: Proceedings of the Royal Society B: Biological Sciences
Proceedings of the Royal Society B: Biological Sciences, Royal Society, The, 2020, 287 (1938), pp.20201876. ⟨10.1098/rspb.2020.1876⟩
Proc Biol Sci
Proceedings of the Royal Society B: Biological Sciences, 2020, 287 (1938), pp.20201876. ⟨10.1098/rspb.2020.1876⟩

High-quality developmental environments often improve individual performance into adulthood, but allocating toward early life traits, such as growth, development rate and reproduction, may lead to trade-offs with late-life performance. It is, therefo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41576e5615413d9018da5f9b9dd3f0dc
https://hal.inrae.fr/hal-02990009

Temporal changes in genetic admixture are linked to heterozygosity and health diagnoses in humans

Autor: Digna R. Velez Edwards, Chun Li, Jacklyn N. Hellwege, Siwei Zhang, Yaomin Xu, Joshua C. Denny, Todd L. Edwards, Dan M. Roden, Brian S. Mautz, Tracy L. McGregor

Reproduction between individuals from different ancestral populations creates genetically admixed offspring. Admixture can have positive and negative impacts on individual health, feeding back to population health. Historical and forced migrations, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1e679a085b5a27bfd33a16e9e2b5cc
https://doi.org/10.1101/697581

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Autor: Dennis O. Mook-Kanamori, J M Gaziano, Harst Pvd., Derek Klarin, K A Birdwell, Josh C. Denny, Martin Farrall, Thibaud Boutin, Najim Lahrouchi, Nabi Shah, Scott M. Damrauer, Cecilia P. Chung, Neil Poulter, Herzig K-H., E E Siew, John Concato, Yan V. Sun, Sara M. Willems, Louise V. Wain, Philip S. Tsao, Massimo Mangino, Wei W-Q., Ioanna Ntalla, Brian S. Mautz, David Schlessinger, Daniel I. Chasman, Branwen J. Hennig, Christopher Newton-Cheh, Michael E. Matheny, Palmer Cna., Caroline Hayward, Zhao J-H., Eleftheria Zeggini, Paul Elliott, C M Lindgren, Praveen Surendran, Csaba P. Kovesdy, Jacob M. Keaton, Chengxiang Qiu, Claudia Langenberg, Christopher Oldmeadow, Stéphanie Debette, D.R. Velez Edwards, Evangelos Evangelou, Howson Jmm., Adriana M. Hung, Yaomin Xu, Nicholas J. Wareham, James P. Cook, Scott L. DuVall, Peter Almgren, Jacklyn N. Hellwege, Sébastien Thériault, Helen R. Warren, Jian'an Luan, Ching-Ti Liu, Christopher J. O'Donnell, Michael Boehnke, Peter S. Sever, Ruifang Li-Gao, Cassianne Robinson-Cohen, Robert A. Scott, Muralidharan Sargurupremraj, Mark J. Caulfield, Jarvelin M-R., Tim D. Spector, Todd L. Edwards, Elena V. Feofanova, Francesco Cucca, Jihwan Park, Savita Karthikeyan, J C Smith, Wilson Pwf., Markku Laakso, Ayush Giri, Christianne L. Roumie, Rojesh Shrestha, Claudia P. Cabrera, Kelly Cho, Laura J. Scott, Elvis A. Akwo, Yu Wang, Tom G. Richardson, Patricia B. Munroe, Eric S. Torstenson, Katalin Susztak, John Attia, Bruce M. Psaty, Aldi T. Kraja, Olle Melander, Nicholas J. Timpson, George Dedoussis, Paul M. Ridker, Niek Verweij, David Conen, Philippe Amouyel, Otis D. Wilson, Nuno Sepúlveda

Publikováno v: NATURE GENETICS
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.51-62. ⟨10.1038/s41588-018-0303-9⟩
Nature Genetics, 51(1), 51
Nature genetics, 51(1), 51-62. Nature Publishing Group
Nature Genetics, 51(1), 51-62. Nature Publishing Group
Giri, A, Hellwege, J N, Keaton, J M, Park, J, Qiu, C, Warren, H R, Torstenson, E S, Kovesdy, C P, Sun, Y V, Wilson, O D, Robinson-Cohen, C, Roumie, C L, Chung, C P, Birdwell, K A, Damrauer, S M, DuVall, S L, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, C P, Wain, L V, Shrestha, R, Mautz, B S, Akwo, E A, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, L J, Luan, J, Zhao, J-H, Willems, S M, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, T S, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, J P, Richardson, T G, Zeggini, E, Scott, R A, Palmer, C N A & Timpson, N J & Wilson, P W F 2019, ' Trans-ethnic association study of blood pressure determinants in over 750,000 individuals ', Nature Genetics, vol. 51, no. 1, pp. 51-62 . https://doi.org/10.1038/s41588-018-0303-9

International audience; In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc65101b526e49b26bca973f7ee89ec

Facultative adjustment of the offspring sex ratio and male attractiveness: a systematic review and meta-analysis

Autor: Brian S. Mautz, Shinichi Nakagawa, Isobel Booksmythe, Jacqueline Davis, Michael D. Jennions

Publikováno v: Biological Reviews. 92:108-134

Females can benefit from mate choice for male traits (e.g. sexual ornaments or body condition) that reliably signal the effect that mating will have on mean offspring fitness. These male-derived benefits can be due to material and/or genetic effects.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::446a0830f574a6d7eadf337d79e0ef80
https://doi.org/10.1111/brv.12220