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pro vyhledávání: '"Brian S. H. Chong"'
Autor:
Yuko Tsukahara, Beatriz Ferran, Erika T. Minetti, Brian S. H. Chong, Adam C. Gower, Markus M. Bachschmid, Reiko Matsui
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 867 (2022)
Liver fibrosis is a sign of non-alcoholic fatty liver disease progression towards steatohepatitis (NASH) and cirrhosis and is accelerated by aging. Glutaredoxin-1 (Glrx) controls redox signaling by reversing protein S-glutathionylation, induced by ox
Externí odkaz:
https://doaj.org/article/cb7319cbe9d445ce80f03a0c9c0d6241
Autor:
Yvonne M. W. Janssen-Heininger, Beatriz Ferrán, Brian S. H. Chong, Yoshimitsu Yura, Richard A. Cohen, Yosuke Watanabe, Colin E. Murdoch, Mark E. McComb, Yuko Tsukahara, Markus Bachschmid, Reiko Matsui, Jessica B. Behring, Ryan D. Johnson, Catherine E. Costello
Publikováno v:
FASEB J
Glutaredoxin-1 (Glrx) is a small cytosolic enzyme that removes S-glutathionylation, glutathione adducts of protein cysteine residues, thus modulating redox signaling and gene transcription. Although Glrx up-regulation prevented endothelial cell (EC)