Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brian S. Freed"'
Autor:
R. Richard L. Hamer, Lawrence L. Martin, John J. Tegeler, Ellen S. Kurtz, Penelope A. Przekop, Mary Ellen Elliott, Luther Hellyer, Steven C. Bailey, Richard C. Allen, Helsley Grover C, John H. White, Brian S. Freed
Publikováno v:
Journal of Medicinal Chemistry. 39:246-252
Hydroxylamine and hydroxamic acid derivatives of a known nonsteroidal antiinflammatory dibenzoxepine series display both cyclooxygenase (CO) and 5-lipoxygenase (5-LO) inhibitory properties. Many of these new dual CO/5-LO inhibitors also exhibit poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3471acc01b0cd7d342a64e3625c94b84
https://doi.org/10.1021/jm950563z
https://doi.org/10.1021/jm950563z
Autor:
Rauckman Barbara S, Brian S. Freed, John J. Tegeler, Gregory H. Merriman, Marie Ortega-Nanos, R. Richard L. Hamer, Luther Hellyer, Ellen S. Kurtz, Steven C. Bailey
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2477-2482
Novel aryl-fused sphingolipids, in which aryl-/heteroaryl-moieties were incorporated into the allylic 4,5,6-positions of sphingosine, were prepared and found to possess good in vitro PKC inhibitory activity. (3-(1-Dodecynyl)phenyl)- and (4- and (5-(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceadbec253667ba3e4cc7eca6f7fb763
https://doi.org/10.1016/0960-894x(95)00427-u
https://doi.org/10.1016/0960-894x(95)00427-u
Autor:
R. Richard L. Hamer, Luther Hellyer, John J. Tegeler, Marie Ortega-Nanos, Penelope A. Przekop, Rauckman Barbara S, Brian S. Freed, Steven C. Bailey, Gregory H. Merriman, Ellen S. Kurtz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2483-2488
Recently we identified three promising topically active antiinflammatory agents ( 2 , 3 , and 4 ) from a series of racemic aryl-sphingolipids that inhibit protein kinase C (PKC). We now wish to report the enantioselective synthesis of the aforementio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::361f411e5c07a3ef8d3394c4d5d432bc
https://doi.org/10.1016/0960-894x(95)00428-v
https://doi.org/10.1016/0960-894x(95)00428-v
Autor:
Penelope A. Przekop, Gregory H. Merriman, Steven C. Bailey, Luther Hellyer, Brian S. Freed, Marie Ortega-Nanos, R. Richard L. Hamer, John J. Tegeler, Ellen S. Kurtz, Rauckman Barbara S
Publikováno v:
ChemInform. 27
Recently we identified three promising topically active antiinflammatory agents ( 2 , 3 , and 4 ) from a series of racemic aryl-sphingolipids that inhibit protein kinase C (PKC). We now wish to report the enantioselective synthesis of the aforementio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bd028e045e24bec382fbbbe3d9f104f
https://doi.org/10.1002/chin.199609278
https://doi.org/10.1002/chin.199609278
Autor:
Steven C. Bailey, Luther Hellyer, Penelope A. Przekop, Lawrence L. Martin, John H. White, Mary Ellen Elliott, Brian S. Freed, Helsley Grover C, R. Richard L. Hamer, Ellen S. Kurtz, Richard C. Allen, John J. Tegeler
Publikováno v:
ChemInform. 27
Hydroxylamine and hydroxamic acid derivatives of a known nonsteroidal antiinflammatory dibenzoxepine series display both cyclooxygenase (CO) and 5-lipoxygenase (5-LO) inhibitory properties. Many of these new dual CO/5-LO inhibitors also exhibit poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39df8bb023c63c090f846186f9796a38
https://doi.org/10.1002/chin.199618158
https://doi.org/10.1002/chin.199618158
Autor:
Erich F. Paulus, Fink David M, Kurys Barbara E, Brian S. Freed, Gregory H. Merriman, Jennifer Varriano, Shelly Pavlek
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647b5231d26336fdbf09555dd1f88c90
https://doi.org/10.1002/chin.200017141
https://doi.org/10.1002/chin.200017141
Autor:
Jennifer Varriano, Brian S. Freed, Kurys Barbara E, Shelly Pavlek, Erich F. Paulus, Gregory H. Merriman, Fink David M
Publikováno v:
Synlett. 2000:137-139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abf231f6758c7691c6b1457bf98bdcc8
https://doi.org/10.1055/s-2000-6462
https://doi.org/10.1055/s-2000-6462