Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Brian S. Cox"'
Autor:
Patricia A Parmelee, Emily A Behrens, Kyrsten Costlow Hill, Brian S Cox, Jason A DeCaro, Francis J Keefe, Dylan M Smith
Publikováno v:
J Gerontol B Psychol Sci Soc Sci
Objectives This research examined main and moderating effects of global depressive symptoms upon in-the-moment associations of pain and affect among individuals with knee osteoarthritis (OA). Effects of depression on short-term change in pain and aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca2ca25f2a16aa1e0704f5e4549c339
https://doi.org/10.1093/geronb/gbab221
https://doi.org/10.1093/geronb/gbab221
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4670 (2009)
BACKGROUND:Yeast (Saccharomyces cerevisiae) prions are efficiently propagated and the on-going generation and transmission of prion seeds (propagons) to daughter cells during cell division ensures a high degree of mitotic stability. The reversible in
Externí odkaz:
https://doaj.org/article/191603b2d1474e8d96aa3a0cb7ded9de
Publikováno v:
PLoS Biology, Vol 2, Iss 4, p E86 (2004)
Many proteins can misfold into beta-sheet-rich, self-seeding polymers (amyloids). Prions are exceptional among such aggregates in that they are also infectious. In fungi, prions are not pathogenic but rather act as epigenetic regulators of cell physi
Externí odkaz:
https://doaj.org/article/7b141c458a474820bf10b30edc58f5d2
Publikováno v:
Molecular Microbiology. 104:125-143
The ability of a yeast cell to propagate [PSI+ ], the prion form of the Sup35 protein, is dependent on the molecular chaperone Hsp104. Inhibition of Hsp104 function in yeast cells leads to a failure to generate new propagons, the molecular entities n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d74758170a1e913734bfc9fde4315e40
https://doi.org/10.1111/mmi.13617
https://doi.org/10.1111/mmi.13617
Autor:
Brian S. Cox, Mick F. Tuite
Publikováno v:
Current Genetics
The AAA+ disaggregase Hsp104 is essential for the maintenance and inheritance of nearly all known prions of the yeast Saccharomyces cerevisiae. Uniquely for [PSI +], the prion form of the Sup35 protein, there seem to be two activities, involving diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef3ff4e01ea0351083c085b885438fb
https://kar.kent.ac.uk/62387/1/10.1007%2Fs00294-017-0714-7.pdf
https://kar.kent.ac.uk/62387/1/10.1007%2Fs00294-017-0714-7.pdf
Publikováno v:
Molecular microbiology. 104(1)
The ability of a yeast cell to propagate [PSI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd0ed8ccb1e6cb5e58207496873294d7
https://pubmed.ncbi.nlm.nih.gov/28073182
https://pubmed.ncbi.nlm.nih.gov/28073182
Publikováno v:
Prion. 1:170-178
The rate of spontaneous change from psi(-) to the psi(+) condition, determined in yeast by states of the Sup35p protein, is briefly discussed together with the conditions necessary for such change to occur. Conditions that promote and which affect th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85d0893934e517f9a1c463bdd9fc66a
https://doi.org/10.4161/pri.1.3.4839
https://doi.org/10.4161/pri.1.3.4839
Publikováno v:
Prion. 9(5)
The year 2015 sees the fiftieth anniversary of the publication of a research paper that underpins much of our understanding of fungal prion biology, namely "ψ, a cytoplasmic suppressor of super-suppressor in yeast" by Brian Cox. Here we show how our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c765837c6ebe211d2c10c9e5fc3afb1
https://pubmed.ncbi.nlm.nih.gov/26645632
https://pubmed.ncbi.nlm.nih.gov/26645632
Autor:
Mick F. Tuite, Brian S. Cox
Publikováno v:
Methods. 39:9-22
The [PSI(+)] prion of the yeast Saccharomyces cerevisiae was first identified by Brian Cox some 40 years ago as a non-Mendelian genetic element that modulated the efficiency of nonsense suppression. Following the suggestion by Reed Wickner in 1994 th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be81768f415fb39140ab5e5b80d7b26b
https://doi.org/10.1016/j.ymeth.2006.04.001
https://doi.org/10.1016/j.ymeth.2006.04.001
Publikováno v:
Journal of Applied Behavior Analysis. 38:533-536
Senior drivers are vulnerable to automobile crashes and subsequent injury and death. Safety belts reduce health risks associated with auto crashes. Therefore, it is important to encourage senior drivers to wear safety belts while driving. Using a rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f203251d28f40c2c1b58986c3b83f23
https://doi.org/10.1901/jaba.2005.34-03
https://doi.org/10.1901/jaba.2005.34-03