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pro vyhledávání: '"Brian S. Chadwick"'
Publikováno v:
Cellular Immunology. 146:1-10
Incubation of murine splenocytes in high concentrations of the lymphokine interleukin 2 leads to the development of cytotoxic effector cells termed lymphokine-activated killer cells. Two populations of blast cells develop within these cultures, one o
Publikováno v:
Journal of Cellular Physiology. 148:485-492
Mouse thymocytes and erythrocytes form rosettes when incubated together at 4 degrees C. The frequency is much higher when the thymocytes and erythrocytes are MHC-identical. If the indolizidine alkaloid swainsonine (SW) is present during rosette forma
Autor:
Richard G. Miller, Brian S. Chadwick
Publikováno v:
Cellular Immunology. 132:168-176
Lymphokine-activated killer cells (LAK) are functionally defined by their ability to mediate the MHC-unrestricted lysis of a range of tumor targets, while sparing normal cells. They can also lyse TNP-modified normal syngeneic lymphoblasts. We show he
Publikováno v:
Cellular immunology. 127(1)
Bone marrow cells from 6- to 8-week-old athymic nude mice were depleted of nylon-wool adherent cells and cultured in vitro at low cell numbers (300 cells/well) in medium supplemented with a supernatant from a thymoma cell line. About 1% of cultured c