Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Brian Revennaugh"'
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103441- (2024)
Summary: While some tumor driver mutations inhibit existing protein-protein interactions (PPIs), others can create neomorph interactions (neoPPIs) not characteristic of the wild-type counterparts. Such tumor-specific neoPPIs may represent targets for
Externí odkaz:
https://doaj.org/article/fd7c37d637974fa7b5103899bb58a316
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110035- (2024)
Summary: Genomic alterations, such as missense mutations, often lead to the activation of oncogenic pathways and cell transformation by rewiring protein-protein interaction (PPI) networks. Understanding how mutant-directed neomorph PPIs (neoPPIs) dri
Externí odkaz:
https://doaj.org/article/29ab20f9157d41b4b17e03eeeafbf58a
Autor:
Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno, Lee A. D. Cooper, Yuhong Du, Fadlo R. Khuri, Haian Fu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Understanding of dysregulation in cancers requires knowledge, beyond cancer genomes, of the interactions of cancer-associated proteins. Here, the authors use high-throughput, time-resolved FRET to map protein–protein interactions to establish a lun
Externí odkaz:
https://doaj.org/article/68054ffe48384c37b6507f6dc7acbd25
Autor:
Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno, Lee A. D. Cooper, Yuhong Du, Fadlo R. Khuri, Haian Fu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14356 (2017); Published: 16 February 2017; Updated: 18 April 2017 The original version of this Article contained an error in the spelling of the author Carlos S. Moreno, which was incorrectly given as Carlos M
Externí odkaz:
https://doaj.org/article/12da3c8ff4c64c0e9a24b64a9111b4c9
Autor:
Xiulei Mo, Andrei A. Ivanov, Haian Fu, Brian Revennaugh, Lee Cooper, Fadlo R. Khuri, Carlos S. Moreno, Lauren Rusnak, Valentina Gonzalez-Pecchi, Margaret A. Johns, Yuhong Du
Motivation As cancer genomics initiatives move toward comprehensive identification of genetic alterations in cancer, attention is now turning to understanding how interactions among these genes lead to the acquisition of tumor hallmarks. Emerging pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fa1d7d4dc8d3cab69fd343c3787a92
https://europepmc.org/articles/PMC6030952/
https://europepmc.org/articles/PMC6030952/
Autor:
Valentina Gonzalez-Pecchi, Margaret A. Johns, Andrei A. Ivanov, Yuhong Du, Wei Zhou, Adam I. Marcus, Elizabeth A. McMillan, Qi Qi, Xiulei Mo, Cau Pham, Haian Fu, Lee Cooper, Songlin Liu, Brian Revennaugh, Michael A. White, Xiaoqian Chen, Philip J. Webber, Carlos S. Moreno, Rina Su, Fadlo R. Khuri, Lauren Rusnak, Zenggang Li, Sahar Harati, Xiang Chen
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
As genomics advances reveal the cancer gene landscape, a daunting task is to understand how these genes contribute to dysregulated oncogenic pathways. Integration of cancer genes into networks offers opportunities to reveal protein–protein interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d2b34d3e270fb29372dc1ff3e4e299
https://doi.org/10.1038/ncomms15350
https://doi.org/10.1038/ncomms15350
Autor:
Cau Pham, Haian Fu, Rina Su, Wei Zhou, Xiaoqian Chen, Fadlo R. Khuri, Lee Cooper, Songlin Liu, Valentina Gonzalez-Pecchi, Margaret A. Johns, Adam I. Marcus, Elizabeth A. McMillan, Brian Revennaugh, Lauren Rusnak, Yuhong Du, Xiang Chen, Zenggang Li, Sahar Harati, Carlos S. Moreno, Michael A. White, Xiulei Mo, Andrei A. Ivanov, Philip J. Webber, Qi Qi
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
As genomics advances reveal the cancer gene landscape, a daunting task is to understand how these genes contribute to dysregulated oncogenic pathways. Integration of cancer genes into networks offers opportunities to reveal protein–protein interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863d08e6693eead3cbce1fc9a47cbbb8
https://doi.org/10.1038/ncomms14356
https://doi.org/10.1038/ncomms14356
Autor:
Haian Fu, Eric Rhoden, Yuhong Du, Raymond Dingledine, Jillian R. Gunther, Sung Hoon Kim, Brian Revennaugh, Terry W. Moore, John A. Katzenellenbogen, Iestyn Lewis
Publikováno v:
SLAS Discovery. 14:181-193
Therapeutic block of estrogen action is typically achieved with conventional antagonists (CAs), compounds that displace estradiol from the estrogen receptor (ER) and induce formation of an ER conformation that cannot bind to coactivator proteins, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0317673cdedff9c9e73dfa8805ed77dc
https://doi.org/10.1177/1087057108329349
https://doi.org/10.1177/1087057108329349