Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brian R. Wynne"'
Autor:
Ying Zhang, Mark Bush, Parto Yazdani, Joyce Zhan, Bo Wen, Veronica Bainbridge, Brian R. Wynne, Samit Joshi, Max Lataillade
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 6, Pp n/a-n/a (2023)
Abstract GSK3640254 (GSK'254) is a novel HIV‐1 maturation inhibitor with pharmacokinetics supporting once‐daily (QD) therapy for HIV‐1 treatment. This thorough QT/corrected QT (QTc) study evaluated the effect of GSK'254 on cardiac repolarizatio
Externí odkaz:
https://doaj.org/article/5191d91a05ac43c2a70b1bf6d821069a
Autor:
Charlotte-Paige Rolle, Mezgebe Berhe, Tulika Singh, Roberto Ortiz, Anson Wurapa, Moti Ramgopal, Dushyantha T Jayaweera, Peter A Leone, Jessica E Matthews, Michael Cupo, Mark R Underwood, Konstantinos Angelis, Brian R Wynne, Deanna Merrill, Christopher Nguyen, Jean van Wyk, Andrew R Zolopa
Publikováno v:
Open Forum Infectious Diseases. 10
BackgroundWe assessed the efficacy and safety of dolutegravir/lamivudine (DTG/3TC) in a US test-and-treat setting at a secondary 48-week time point of the multicenter, single-arm, phase IIIb STAT study.MethodsParticipants were eligible adults newly d
Autor:
Manyu Prakash, Richard Grove, Brian R Wynne, Choy Man, Jean A van Wyk, Clifford B Jones, Chinyere Okoli, Emilio Letang, Mounir Ait-Khaled, Andrew Clark
Publikováno v:
Open Forum Infectious Diseases. 9
Background The proportion of older adults living with HIV is growing, increasing the focus of managing age-related comorbidities and polypharmacy while maintaining virologic suppression. DTG/3TC is an international guidelines–recommended 2-drug reg