Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Brian R. Wynne"'
1
Akademický článek
Effects of the HIV‐1 maturation inhibitor GSK3640254 on QT interval in healthy participants
Autor: Ying Zhang, Mark Bush, Parto Yazdani, Joyce Zhan, Bo Wen, Veronica Bainbridge, Brian R. Wynne, Samit Joshi, Max Lataillade
Publikováno v: Pharmacology Research & Perspectives, Vol 11, Iss 6, Pp n/a-n/a (2023)
Abstract GSK3640254 (GSK'254) is a novel HIV‐1 maturation inhibitor with pharmacokinetics supporting once‐daily (QD) therapy for HIV‐1 treatment. This thorough QT/corrected QT (QTc) study evaluated the effect of GSK'254 on cardiac repolarizatio
Externí odkaz: https://doaj.org/article/5191d91a05ac43c2a70b1bf6d821069a
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2
1267. Efficacy and Safety of Switching to DTG/3TC in Virologically Suppressed PLWH by Age, Including Those Aged ≥65 Years: Pooled Results from the TANGO and SALSA Studies
Autor: Manyu Prakash, Richard Grove, Brian R Wynne, Choy Man, Jean A van Wyk, Clifford B Jones, Chinyere Okoli, Emilio Letang, Mounir Ait-Khaled, Andrew Clark
Publikováno v: Open Forum Infectious Diseases. 9
Background The proportion of older adults living with HIV is growing, increasing the focus of managing age-related comorbidities and polypharmacy while maintaining virologic suppression. DTG/3TC is an international guidelines–recommended 2-drug reg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec58ee5688d5d9b4949f302d322e7462
https://doi.org/10.1093/ofid/ofac492.1098
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3
Sustained Virologic Suppression With Dolutegravir/Lamivudine in a Test-and-Treat Setting Through 48 Weeks
Autor: Charlotte-Paige Rolle, Mezgebe Berhe, Tulika Singh, Roberto Ortiz, Anson Wurapa, Moti Ramgopal, Dushyantha T Jayaweera, Peter A Leone, Jessica E Matthews, Michael Cupo, Mark R Underwood, Konstantinos Angelis, Brian R Wynne, Deanna Merrill, Christopher Nguyen, Jean van Wyk, Andrew R Zolopa
Publikováno v: Open Forum Infectious Diseases. 10
BackgroundWe assessed the efficacy and safety of dolutegravir/lamivudine (DTG/3TC) in a US test-and-treat setting at a secondary 48-week time point of the multicenter, single-arm, phase IIIb STAT study.MethodsParticipants were eligible adults newly d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ba11ab6a80a3b2169a20e556ad0bf79
https://doi.org/10.1093/ofid/ofad101
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4
Akademický článek
Dolutegravir/Lamivudine Efficacy and Safety Outcomes in People With HIV-1 With or Without Historical Resistance Results at Screening: 48-Week Pooled Analysis.
Autor: Scholten, Stefan1 (AUTHOR), Cahn, Pedro2 (AUTHOR), Portilla, Joaquín3 (AUTHOR), Bisshop, Fiona4 (AUTHOR), Hodder, Sally5 (AUTHOR), Ruane, Peter6 (AUTHOR), Kaplan, Richard7 (AUTHOR), Wynne, Brian R8 (AUTHOR), Man, Choy Y8 (AUTHOR), Grove, Richard9 (AUTHOR), Wang, Ruolan8 (AUTHOR), Jones, Bryn10 (AUTHOR), Ait-Khaled, Mounir10 (AUTHOR), Kisare, Michelle10 (AUTHOR) michelle.o.kisare@viivhealthcare.com, Okoli, Chinyere10 (AUTHOR)
Publikováno v: Open Forum Infectious Diseases. Jul2024, Vol. 11 Issue 7, p1-8. 8p.
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5
Akademický článek
Effects of the HIV‐1 maturation inhibitor GSK3640254 on QT interval in healthy participants.
Autor: Zhang, Ying1 (AUTHOR) ying.16.zhang@gsk.com, Bush, Mark2 (AUTHOR), Yazdani, Parto3 (AUTHOR), Zhan, Joyce1 (AUTHOR), Wen, Bo1 (AUTHOR), Bainbridge, Veronica4 (AUTHOR), Wynne, Brian R.2 (AUTHOR), Joshi, Samit5 (AUTHOR), Lataillade, Max5 (AUTHOR)
Publikováno v: Pharmacology Research & Perspectives. Dec2023, Vol. 11 Issue 6, p1-10. 10p.
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6
Akademický článek
Sustained Virologic Suppression With Dolutegravir/Lamivudine in a Test-and-Treat Setting Through 48 Weeks.
Autor: Rolle, Charlotte-Paige1 (AUTHOR) crolle@oicorlando.com, Berhe, Mezgebe2 (AUTHOR), Singh, Tulika3 (AUTHOR), Ortiz, Roberto4 (AUTHOR), Wurapa, Anson5 (AUTHOR), Ramgopal, Moti6 (AUTHOR), Jayaweera, Dushyantha T7 (AUTHOR), Leone, Peter A8 (AUTHOR), Matthews, Jessica E8 (AUTHOR) crolle@oicorlando.com, Cupo, Michael9 (AUTHOR), Underwood, Mark R8 (AUTHOR), Angelis, Konstantinos10 (AUTHOR), Wynne, Brian R8 (AUTHOR), Merrill, Deanna8 (AUTHOR), Nguyen, Christopher8 (AUTHOR), Wyk, Jean van11 (AUTHOR), Zolopa, Andrew R8,12 (AUTHOR)
Publikováno v: Open Forum Infectious Diseases. Mar2023, Vol. 10 Issue 3, p1-9. 9p.
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7
Akademický článek
11. TÜRKİYE EKMUD BİLİMSEL KONGRESİ - 03-07 MAYIS 2023.
Publikováno v: Mediterranean Journal of Infection, Microbes & Antimicrobials. 2023 Supplement, Vol. 12, p1-289. 296p.
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8
Akademický článek
IDWeek Advancing Science, Improving Care 2022 Abstract.
Publikováno v: Open Forum Infectious Diseases. 2022 Supplement, Vol. 9, pS1-S936. 2220p.
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9
Akademický článek
Relative Bioavailability of a Dolutegravir Dispersible Tablet and the Effects of Low‐ and High‐Mineral‐Content Water on the Tablet in Healthy Adults.
Autor: Buchanan, Ann M.1 ann.m.buchanan@viivhealthcare.com, Holton, Michael2, Conn, Ian2, Davies, Mark3, Choukour, Mike4, Wynne, Brian R.5
Publikováno v: Clinical Pharmacology in Drug Development. Nov2017, Vol. 6 Issue 6, p577-583. 7p.
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