Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Brian R. Worth"'
Autor:
Brian R. Worth, James P. Kutney, G. Eigendorf, Anthony H. Conner, Bhimsen A. Nagasampagi, John W. Rowe
Publikováno v:
Helvetica Chimica Acta. 64:1183-1207
Eleven new triterpenes with the lanostene-type skeleton were isolated from the benzene extract of western white pine bark. Their structures were determined mainly on the basis of physical and spectral data.
Autor:
A. H. Ratcliffe, Toshio Honda, Isamu Itoh, Brian R. Worth, John Balsevich, Gordon H. Bokelman, Toshihiko Hibino, James P. Kutney
Publikováno v:
Canadian Journal of Chemistry. 56:62-70
Studies involving selective functionalization of the indole unit in a number of bisindole alkaloids and related synthetic derivatives are described. These investigations include such reagents as tert-butyl hydroperoxide, which provides an efficient p
Autor:
Brian R. Worth, Norman G. Lewis, Toshio Honda, James P. Kutney, Kenneth L. Stuart, Lewis S. L. Choi, Toshitsugu Sato
Publikováno v:
Helvetica Chimica Acta. 65:2088-2101
Cell-free systems from Catharanthus roseus plants are utilized for various studies relating to the biosynthesis of indole alkaloids. Tryptamine (5) and secologanin (6), two fundamental building units, are shown to be incorporated into the alkaloid vi
Autor:
Brian R. Worth, James P Kutney, Lewis S L Choi, Stephen K. Sleigh, Friedrich Constabel, K. B. Chatson, Pawel Kolodziejczyk, Wolfgang G. W. Kurz, Kenneth L. Stuart
Publikováno v:
Phytochemistry. 19:2583-2587
Several hundred serially cultured cell suspensions derived from three cultivars of periwinkle ( Catharanthus roseus ) were established in Gamborg's B 5 medium and then transferred to Zenk's alkaloid production medium. Total alkaloid concentration ran
Publikováno v:
Canadian Journal of Chemistry. 60:323-326
Reaction of 1,2- and 1,6-dihydro-3-ethyl-N-methyl pyridine tricarbonylchromium(0) complexes with methyllithium at low temperature afforded a high yield of dimeric tricarbonylchromium(0) complexes. Structures of the latter products were established by
Autor:
Friedrich Constabel, K. B. Chatson, Kenneth L. Stuart, W. G. W. Kurz, Pawel Kolodziejczyk, James P. Kutney, Brian R. Worth, Lewis S. L. Choi, Stephen K. Sleigh
Publikováno v:
Phytochemistry. 19:2589-2595
A detailed study of one cell line (coded as 943) of Catharanthus roseus cell cultures has revealed the presence of the following alkaloids: ajmalicine, vallesiachotamine, horhammerinine, horhammericine, vindolinine, 19- epi - vindolinine, 19-acetoxy-
Autor:
Friedrich Constabel, Pawel Kolodziejczyk, James P. Kutney, Lewis S. L. Choi, Wolfgang G. W. Kurz, Kenneth L. Stuart, K. B. Chatson, Stephen K. Sleigh, Brian R. Worth
Publikováno v:
Helvetica Chimica Acta. 63:1891-1896
The 953 cell line, one of the cell lines from Catharanthus roseus, has been investigated in terms of its ability to produce indole alkaloids. Various parameters (mitotic index, pH, cell dry weight, growth period) were evaluated in the fermentation pr
Autor:
Gary M. Hewitt, Brian R. Worth, Phillip J. Salisbury, R. Gordon, Dennis W. Martens, James A. Servizi, James P. Kutney, Mahatam Singh
Publikováno v:
Canadian Journal of Chemistry. 59:2334-2341
A study related to biological detoxification of kraft pulp mill effluent is presented. A series of fungal and bacterial preparations were evaluated for their action on dehydroabietic acid (DHA), one of the effluent constituents toxic to fish. Mortier
Isolation and characterization of natural products from plant tissue cultures of Maytenus buchananii
Autor:
Kristina Nilsson, Michael H. Beale, William T. Chalmers, James P. Kutney, Phillip M. Townsley, Giullo G. Jacoli, Brian R. Worth, Kenneth L. Stuart, Phillip J. Salisbury
Publikováno v:
Phytochemistry. 20:653-657
Explants of Maytenus buchananii were induced to form a callus aid subsequently to form suspension cultures on a wide variety of media. Culture extracts showed cytotoxic activity, but examination by TLC did not indicate the presence of maytansine. Iso
Autor:
James P. Kutney, Brian R. Worth, Masaki Noda, Ying Hung So, Robert Greenhouse, A. Zanarotti, William R. Cullen, Vicente E. Ridaura-Sanz, Rodney A. Badger
Publikováno v:
Canadian Journal of Chemistry. 57:300-303
Controlled reduction of N-methyl-3-ethylpyridinium iodide afforded the corresponding 1,2-dihydropyridine which was stabilised by complexation to give 1,2- and 1,6-dihydro-3-ethyl-N-methylpyridinetricarbonylchromium(0). These stable, isomeric complexe