Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Brian R. Rosborough"'
Autor:
Georgios D Kitsios, Dario A. A. Vignali, Feng Shan, Callie Drohan, N. Bensen, Haopu Yang, Rebecca S. DeSensi, William Bain, Barbara Methé, Yingze Zhang, Bryan J. McVerry, Tullia C. Bruno, Caleb Lampenfeld, Nameer Al-Yousif, Alison Morris, Tomeka Suber, Carly Cardello, Faraaz Ali Shah, Janet S. Lee, Brian R. Rosborough, Prabir Ray, Anthony R. Cillo, Creg J. Workman, Ashwin Somasundaram, Caitlin Schaefer, Anuradha Ray
Publikováno v:
Annals of the American Thoracic Society
Rationale: There is an urgent need for improved understanding of the mechanisms and clinical characteristics of acute respiratory distress syndrome (ARDS) due to coronavirus disease (COVID-19). Objectives: To compare key demographic and physiologic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273fe45c58785d5d19507e15725ae7a2
http://europepmc.org/articles/PMC8328355
http://europepmc.org/articles/PMC8328355
Autor:
Jie Chen, Y. Jiang, Brian R. Rosborough, Anuradha Ray, Bryan J. McVerry, Wei Chen, Prabir Ray, Georgios D Kitsios
Publikováno v:
D35. LUNG INJURY AND REPAIR: CELLULAR MECHANISMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f0f0dc46ea3fc2ed40db948948710d
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6541
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6541
Autor:
Wei Chen, Anuradha Ray, Yale Jiang, Bryan J. McVerry, Rama K. Mallampalli, Jie Chen, Prabir Ray, Janet S. Lee, Brian R. Rosborough, Georgios D Kitsios, Sudipta Das
Publikováno v:
JCI Insight
Acute respiratory distress syndrome (ARDS) results from overwhelming pulmonary inflammation. Prior bulk RNA sequencing provided limited insights into ARDS pathogenesis. We used single cell RNA sequencing to probe ARDS at a higher resolution. PBMCs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e1deaa414954731d54899888228926
https://pubmed.ncbi.nlm.nih.gov/32554932
https://pubmed.ncbi.nlm.nih.gov/32554932
Autor:
Bryan J. McVerry, Brian R. Rosborough, Sarah F. Rapport, Anuradha Ray, Yale Jiang, Prabir Ray, Wei Chen
Publikováno v:
D32. ACUTE LUNG INJURY AND ARDS: CLINICAL AND MECHANISTIC STUDIES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0aa23726a3019c59d979f8e2609c91c
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6152
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6152
Autor:
Brian R Rosborough, Jie Chen, Yale Jiang, Georgios Kitsios, Bryan McVerry, Janet S Lee, Anuradha Ray, Wei Chen, Prabir Ray
Publikováno v:
The Journal of Immunology. 204:69.19-69.19
The acute respiratory distress syndrome (ARDS) is a common etiology of acute respiratory failure that results from overwhelming pulmonary inflammation. Since prior bulk RNA sequence analyses have provided limited insights into ARDS pathogenesis, we u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ed79147b207ac8427380517816b972
https://doi.org/10.4049/jimmunol.204.supp.69.19
https://doi.org/10.4049/jimmunol.204.supp.69.19
Autor:
Dirk J. van der Windt, Brian R. Rosborough, Samer Tohme, Allan Tsung, Hai Huang, Heth R. Turnquist, Donna Beer-Stolz, Sheng Tai, Hui-Wei Chen, Patricia Loughran, Vikas Sud, Hamza O. Yazdani
Publikováno v:
Journal of hepatology.
Background & Aims Neutrophils and liver sinusoidal endothelial cells (LSECs) both contribute to sterile inflammatory injury during ischemia/reperfusion (I/R), a well-known liver surgical stress. Interleukin-33 (IL-33) has been shown to drive neutroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd526adc68635c064ea2144df40d9c9
https://pubmed.ncbi.nlm.nih.gov/28943296
https://pubmed.ncbi.nlm.nih.gov/28943296
Autor:
Jeremy M. Lott, Brian R. Rosborough, Bruce R. Blazar, Benjamin M. Matta, Lisa R. Mathews, Quan Liu, Heth R. Turnquist
Publikováno v:
The Journal of Immunology. 193:4010-4020
IL-33 is a recently characterized IL-1 family member that is proposed to function as an alarmin, or endogenous signal of cellular damage, as well as act as a pleiotropic cytokine. The ability of IL-33 to potentiate both Th1 and Th2 immunity supports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e792c0e61ddbe5a143e98726cc09ffc1
https://doi.org/10.4049/jimmunol.1400481
https://doi.org/10.4049/jimmunol.1400481
Autor:
Quan Liu, Dàlia Raïch-Regué, Brian R. Rosborough, Raman Venkataramanan, Heth R. Turnquist, Angus W. Thomson
Publikováno v:
American Journal of Transplantation. 14:2173-2180
The mechanistic/mammalian target of rapamycin (mTOR) is inhibited clinically to suppress T cell function and prevent allograft rejection. mTOR is the kinase subunit of two mTOR-containing complexes, mTOR complex (mTORC) 1 and 2. Although mTORC1 is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b061acf865a5a6c41832d5e1ea56b0c3
https://doi.org/10.1111/ajt.12799
https://doi.org/10.1111/ajt.12799
Publikováno v:
Transplantation. 97:367-379
Regulatory myeloid cells (RMC) are emerging as novel targets for immunosuppressive (IS) agents and hold considerable promise as cellular therapeutic agents. Herein, we discuss the ability of regulatory macrophages (Mreg), regulatory dendritic cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9512b3f95e40eae1dcaeadc79877c932
https://doi.org/10.1097/tp.0b013e3182a860de
https://doi.org/10.1097/tp.0b013e3182a860de
Autor:
Heth R. Turnquist, Angus W. Thomson, Brian R. Rosborough, A. Jake Demetris, Kathryn J. Wood, Foo Y. Liew, Zhiliang Wang, Kumiko Isse, Donna B. Stolz, Quan Liu, Zhenlin Zhao, Xin Xiao Zheng, Megan Lang, A. Castellaneta
IL-33 administration is associated with facilitation of Th2 responses and cardioprotective properties in rodent models. However, in heart transplantation, the mechanism by which IL-33, signaling through ST2L (the membrane-bound form of ST2), promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b30c6754dfff9e8a7da0294f3232dc4
https://ora.ox.ac.uk/objects/uuid:49cfaaf3-7de3-4f0c-b665-8dd6c6dd96f8
https://ora.ox.ac.uk/objects/uuid:49cfaaf3-7de3-4f0c-b665-8dd6c6dd96f8
