Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brian R. Pearce"'
Autor:
Jeff S Davies, Seo-Kyung Chung, Rhys H Thomas, Angela Robinson, Carrie L Hammond, Jonathan G L Mullins, Eloisa Carta, Brian R Pearce, Kirsten Harvey, Robert J Harvey, Mark I Rees
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 3 (2010)
Human startle disease, also known as hyperekplexia (OMIM 149400), is a paroxysmal neurological disorder caused by defects in glycinergic neurotransmission. Hyperekplexia is characterised by an exaggerated startle reflex in response to tactile or acou
Externí odkaz:
https://doaj.org/article/ba58d2bc7f0a425cad44123b79781c6e
Autor:
Robert J Harvey, Eloisa Carta, Brian R Pearce, Seo-Kyung Chung, Stéphane Supplisson, Mark I Rees, Kirsten Harvey
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 1 (2008)
Defects in mammalian glycinergic neurotransmission result in a complex motor disorder characterized by neonatal hypertonia and an exaggerated startle refl ex, known as hyperekplexia (OMIM 149400). This affects newborn children and is characterized by
Externí odkaz:
https://doaj.org/article/4e27d8c72fd3467f956eb43c46d6ea0c
Autor:
Gary R. Dutton, Brian R. Pearce
Publikováno v:
FEBS Letters. 135:215-218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab31f7b27e8eee24433c9ecde102e103
https://doi.org/10.1016/0014-5793(81)80980-5
https://doi.org/10.1016/0014-5793(81)80980-5
Autor:
Gary R. Dutton, Brian R. Pearce
Publikováno v:
Brain research. 255(3)
The effects of l-glutamate on the spontaneous release of [3H]GABA from cerebellar neurons in well characterized cerebellar monolayer cultures were investigated. The release process was dependent on Ca2+, elicited by neuronal depolarization and specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5e2cf2ab4d77f36c2d715450ec37cd
https://pubmed.ncbi.nlm.nih.gov/6121612
https://pubmed.ncbi.nlm.nih.gov/6121612
Publikováno v:
Journal of neurochemistry. 41(1)
We examined the ability of developing cerebellar cell cultures to synthesize a 71,000 MW stress protein (SP71) in response to heat shock and Cd2+ treatment. The induction of SP71 synthesis appeared to be dependent on both the age of the culture and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb835f05e40f32c97232b9bc4d95840c
https://pubmed.ncbi.nlm.nih.gov/6864227
https://pubmed.ncbi.nlm.nih.gov/6864227
Publikováno v:
Journal of neurochemistry. 40(3)
The effect of tetanus toxin pretreatment on K+-stimulated [3H]gamma-aminobutyric acid release from neuron-enriched cerebellar cell cultures at various stages during their development in vitro was assessed. Tetanus toxin had little inhibitory effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c384a0d736d44feef12cf8801fce8621
https://pubmed.ncbi.nlm.nih.gov/6827285
https://pubmed.ncbi.nlm.nih.gov/6827285
Publikováno v:
European journal of pharmacology. 82(3-4)
We investigated the effect of GABA, muscimol and THIP on the K+ -stimulated and spontaneous release of [3H]GABA from neuron-enriched cell cultures of the rat cerebellum. Each agonist produced significant reductions in evoked [3H]GABA without causing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26f1de8109058f2da84b8d0051b27ea
https://pubmed.ncbi.nlm.nih.gov/6290234
https://pubmed.ncbi.nlm.nih.gov/6290234