Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Brian R. Linton"'
Publikováno v:
Journal of Chemical Education. 92:135-138
A discovery chemistry laboratory has been developed for the introductory organic chemistry student to investigate the concepts of polarity, miscibility, solubility, and density. The simple procedure takes advantage of the solubility of two colored dy
Publikováno v:
Chemistry - A European Journal. 19:15101-15104
Autor:
Anthony J. Metrano, Christopher R. Shugrue, Justin R. DeFrancisco, Brian R. Linton, Benjamin D. Brink, R. S. Nomoto
Publikováno v:
Organicbiomolecular chemistry. 14(7)
Hydrogen/deuterium (H/D) exchange can be a sensitive technique for measuring the strength of hydrogen bonding to neutral organic nitro and fluoro groups. The slower rates of reaction in comparison to suitable controls suggest that hydrogen bonding is
Autor:
Timothy J. Cashman, Brian R. Linton
Publikováno v:
Organic Letters. 9:5457-5460
Cystine peptides have been shown to adopt conformations in organic solvents that mimic small beta-sheets. Relative hydrogen bond strengths, beta-strand aggregation, and the identity of individual hydrogen bond donors and acceptors have been identifie
Autor:
Catherine A. Evans, Elizabeth A. Richardson, Scott J. Miller, Michael H. Reutershan, Kristen R. Brownell, Brian R. Linton, Charles W. Ashley, Christopher M. Aderman
Publikováno v:
Tetrahedron Letters. 48:1993-1997
Peptide-based catalysts have been developed that promote the asymmetric Michael addition of nitroalkanes. The most effective peptides contain a β-turn structural element as well as a basic histidine and an arylsulfonamide-protected arginine. Excelle
Publikováno v:
Chemistry - A European Journal. 6:2449-2455
Nitronate anions were shown to form complexes in DMSO with hydrogen-bonding receptors such as 1,3-dimethylthiourea 1 (K(a)= 120M(-1)) and bicyclic guanidinium 2 (K(a) = 3200M(-1)). A ditopic bis-thiourea exhibited increased association with substrate
Autor:
Brian R. Linton, Andrew D. Hamilton
Publikováno v:
Current Opinion in Chemical Biology. 3:307-312
A combinatorial approach to receptor design provides an expedient method to discover the most effective host-guest complexes from within a library. Recent advances focus on generation of larger libraries, facile detection, combinatorial catalysis and
Autor:
Andrew D. Hamilton, Brian R. Linton
Publikováno v:
Tetrahedron. 55:6027-6038
Isothermal titration calorimetry was utilized to study the association between a series of guanidinium derivatives and tetrabutylammonium acetate. This technique provides a measure of association strength, stoichiometry of binding, as well as thermod
Autor:
Brian R. Linton, N. Balabai, David H. Waldeck, Satyam Priyadarshy, and A. P. Sukharevsky, Andrew M. Napper
Publikováno v:
The Journal of Physical Chemistry B. 102:9617-9624
The structure and dynamics of organic dye molecules included in β-cyclodextrin are studied using spectroscopic measurements and theoretical models. The effect of the charge and the size of the guest molecule on the properties of the host−guest com
Autor:
Ian Read, David H. Waldeck, Alexander P. Sukharevsky, and Andrew D. Hamilton, Brian R. Linton
Publikováno v:
The Journal of Physical Chemistry B. 102:5394-5403
A direct temporal measurement of the internal motion of a host−guest bimolecular complex is reported. Time-resolved polarization spectroscopy is used to monitor the motion of a guest chromophore, anthracene-1,3-dicarboxylate, bound to a bis(guanidi