Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Brian R. Keegan"'
Autor:
Robert S. Kirsner, Aliette Espinosa, Joshua D. Fox, Flor Macquhae, Carmen Perez, Paolo Romanelli, Brian R. Keegan, Katherine L. Baquerizo-Nole, Julia Escandon
Publikováno v:
International Wound Journal. 13:963-966
Venous leg ulcers (VLUs) have higher tumor necrosis factor-α (TNF-α) levels compared with normal skin. Refractory VLUs of long duration have higher TNF-α levels compared with VLUs of shorter duration. As up to 75% of VLUs fail to heal with standar
Publikováno v:
Developmental Cell. 15(6):923-934
SummaryHow adjacent organ fields communicate during development is not understood. Here, we identify a mechanism in which signaling within the forelimb field restricts the potential of the neighboring heart field. In zebrafish embryos deficient in re
Publikováno v:
Fertility and Sterility. 88:1583-1588
To reevaluate clinical management of isolated teratozoospermia, in couples initiating IVF.Retrospective analysis of fertility indices in 535 cycles.A large, university-based fertility center.Consecutive couples (n = 495) who had a semen analysis usin
Autor:
William Fangman, Seth J. Orlow, Julie V. Schaffer, Hideko Kamino, Helen T. Shin, Brian R. Keegan
Publikováno v:
Pediatric Dermatology. 24:621-627
We describe two young children who developed relapsing, pruritic, papulovesicular eruptions in multiple bands along Blaschko lines on the neck, trunk, and extremities. Skin specimens in both revealed spongiotic dermatitis. This represents the first r
Publikováno v:
Development. 131:3081-3091
Organogenesis requires the specification of a variety of cell types and the organization of these cells into a particular three-dimensional configuration. The embryonic vertebrate heart is organized into two major chambers, the ventricle and atrium,
Autor:
Deborah Yelon, Diana H. Lee, Brian R. Keegan, Didier Y.R. Stainier, David S. Koos, Robert K. Ho, Jessica L. Feldman
Publikováno v:
Development. 129:1623-1632
Precise temporal and spatial control of transcription is a fundamental component of embryonic development. Regulation of transcription elongation can act as a rate-limiting step during mRNA synthesis. The mechanisms of stimulation and repression of t
Autor:
William Bleazard, Brian R. Keegan, Ellen Brisch, Janet M. Shaw, Greg J. Hermann, John Thatcher, Denichiro Otsuga
Publikováno v:
The Journal of Cell Biology
The Saccharomyces cerevisiae Dnm1 protein is structurally related to dynamin, a GTPase required for membrane scission during endocytosis. Here we show that Dnm1p is essential for the maintenance of mitochondrial morphology. Disruption of the DNM1 gen
Publikováno v:
Science (New York, N.Y.). 307(5707)
Organogenesis begins with specification of a progenitor cell population, the size of which provides a foundation for the organ's final dimensions. Here, we present a new mechanism for regulating the number of progenitor cells by limiting their densit
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 67
Publikováno v:
Molecular biology of the cell. 9(4)
In wild-type yeast mitochondrial inheritance occurs early in the cell cycle concomitant with bud emergence. Cells lacking thePTC1 gene initially produce buds without a mitochondrial compartment; however, these buds later receive part of the mitochond