Zobrazeno 1 - 10 of 187 pro vyhledávání: '"Brian R. Curtis"'
1
Anchoring IgG-degrading enzymes to the surface of platelets selectively neutralizes antiplatelet antibodies
Autor: Donald R. Lynch, Emily N. Stringham, Boya Zhang, Ginette Balbin-Cuesta, Brian R. Curtis, Joseph S. Palumbo, Colin F. Greineder, Benjamin E. Tourdot
Publikováno v: Blood Advances. 6:4645-4656
Immune thrombocytopenia (ITP) is an acquired bleeding disorder characterized by immunoglobulin G (IgG)–mediated platelet destruction. Current therapies primarily focus on reducing antiplatelet antibodies using immunosuppression or increasing platel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb17c278eeaab7be39df7a72080bde77
https://doi.org/10.1182/bloodadvances.2022007195
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3
Generation of ‘designer erythroblasts’ lacking one or more blood group systems from CRISPR/Cas9 gene‐edited human‐induced pluripotent stem cells
Autor: Peter J. Newman, Brian R. Curtis, Nanyan Zhang, Gregory A. Denomme, Priyanka Pandey
Publikováno v: Journal of Cellular and Molecular Medicine
Despite the recent advancements in transfusion medicine, red blood cell (RBC) alloimmunization remains a challenge for multiparous women and chronically transfused patients. At times, diagnostic laboratories depend on difficult‐to‐procure rare re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa23a71145a524526414fadc106d7fb8
https://doi.org/10.1111/jcmm.16872
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5
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia
Autor: Eugene Schneider, Li-Jung Tai, Sebastien A. Burel, Padmakumar Narayanan, Joseph A. Tami, Lijiang Shen, Joseph L. Witztum, T. Jesse Kwoh, Scott P. Henry, Suzanne Paz, Brett P. Monia, Steven G. Hughes, Jeffery A Engelhardt, Sanford J. Shattil, Shuting Xia, Todd Machemer, Brian R. Curtis
Publikováno v: Nucleic Acid Therapeutics. 30:94-103
Inotersen, a 2'-O-methoxyethyl (2'-MOE) phosphorothioate antisense oligonucleotide, reduced disease progression and improved quality of life in patients with hereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN) in the NEURO-TTR and NEU
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ffffb1daa283b051e7ec72a1e47a2
https://doi.org/10.1089/nat.2019.0829
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7
Post-Transfusion Purpura: Current Perspectives
Autor: Jaleah Hawkins, Brian R. Curtis, Richard H. Aster
Publikováno v: Journal of Blood Medicine. 10:405-415
Post transfusion purpura (PTP) is an uncommonly reported post transfusion adverse event that can present with severe thrombocytopenia; sometimes resulting in significant bleeding and hemorrhage. Its diagnosis can be elusive given its substantial symp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99b3e25c8614d13b180a91767fc64be9
https://doi.org/10.2147/jbm.s189176
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