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pro vyhledávání: '"Brian R. Crump"'
Publikováno v:
Organic Process Research & Development. 17:1277-1286
This paper describes the influence of key reaction parameters on the development of a rate model which can be used to forecast starting material conversion independent of scale. A nitro reduction was examined via first principles reaction progress mo
Autor:
Kevin R. Campos, Felix Spindler, Yongkui Sun, J. Christopher McWilliams, Brian D. Phenix, Cheng-yi Chen, C. Scott Shultz, Shane W. Krska, Brian R. Crump, Artis Klapars, Daniel Zewge, Debra J. Wallace
Publikováno v:
Organic Process Research & Development. 13:84-90
Taranabant (1) is a cannabinoid-1 receptor (CB1R) inverse agonist that was recently in late-stage clinical development for the treatment of obesity. The previously employed synthesis exhibited a number of shortcomings for continuing development, and
Autor:
Debra J. Wallace, Kevin R. Campos, C. Scott Shultz, Artis Klapars, Daniel Zewge, Brian R. Crump, Brian D. Phenix, J. Christopher McWilliams, Shane Krska, Yongkui Sun, Cheng-yi Chen, Felix Spindler
Publikováno v:
Organic Process Research & Development; Jan2009, Vol. 13 Issue 1, p84-90, 7p