Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Brian R Hoffmann"'
Autor:
Eric C Exner, Aron M Geurts, Brian R Hoffmann, Marc Casati, Timothy Stodola, Nikita R Dsouza, Michael Zimmermann, Julian H Lombard, Andrew S Greene
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232067 (2020)
The heptapeptide angiotensin-(1-7) (Ang-(1-7)) is protective in the cardiovascular system through its induction of vasodilator production and angiogenesis. Despite acting antagonistically to the effects of elevated, pathophysiological levels of angio
Externí odkaz:
https://doaj.org/article/7d9ac7567d2d453b8563af686f8ac3f7
Autor:
Anthony R Prisco, John D Bukowy, Brian R Hoffmann, Jamie R Karcher, Eric C Exner, Andrew S Greene
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94599 (2014)
Diabetes Mellitus (DM) has reached epidemic levels globally. A contributing factor to the development of DM is high blood glucose (hyperglycemia). One complication associated with DM is a decreased angiogenesis. The Matrigel tube formation assay (TFA
Externí odkaz:
https://doaj.org/article/56f50220b18240449ea0e80f008dd84d
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32762 (2012)
Thrombospondin-1 (TSP-1) is known to be subject to three unusual carbohydrate modifications: C-mannosylation, O-fucosylation, and O-glucosylation. We now describe a fourth: O-β-N-acetylglucosaminylation. Previously, O-β-N-acetylglucosamine (O-β-Gl
Externí odkaz:
https://doaj.org/article/187c02e5708e4db0a15177d03bfa8f77
Autor:
Kaitlyn Thatcher, Carol R. Mattern, Daniel Chaparro, Veronica Goveas, Michael R. McDermott, Jessica Fulton, Joshua D. Hutcheson, Brian R. Hoffmann, Joy Lincoln
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 8, p 355 (2023)
Organization of extracellular matrix (ECM) components, including collagens, proteoglycans, and elastin, is essential for maintaining the structure and function of heart valves throughout life. Mutations in ECM genes cause connective tissue disorders,
Externí odkaz:
https://doaj.org/article/2d6f5df9379543fbbdfb52af7c2481e5
Autor:
Satoshi Shimada, Brian R. Hoffmann, Chun Yang, Theresa Kurth, Andrew S. Greene, Mingyu Liang, Ranjan K. Dash, Allen W. Cowley
Publikováno v:
bioRxiv
In the present study, novel methods were developed which allowed continuous (24/7) measurement of blood pressure (BP) and renal blood flow (RBF) in freely moving rats and the intermittent collection of arterial and renal venous blood to estimate kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73fcbc2a3df481d549401f3daf665a2
https://doi.org/10.1101/2023.01.18.524636
https://doi.org/10.1101/2023.01.18.524636
Autor:
Satoshi Shimada, Brian R Hoffmann, Andrew S Greene, Mingyu Liang, Ranjan K Dash, Allen W Cowley
Publikováno v:
Hypertension. 79
Goal: The effects of a high salt diet on renal cortical ( Cx ) and outer medulla ( OM ) tissue metabolism of normal age matched male Sprague-Dawley rats (SD; 15-16 wk age; n-5) was determined with rats fed 0.4% NaCl (LS) and after switching to 4.0% N
Autor:
Brian R. Hoffmann, Satoshi Shimada, Andrew S. Greene, Mingyu Liang, Ranjan Dash, Allen Cowley
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Kidney360
Background. The 5/6 nephrectomy (5/6Nx) rat model recapitulates many elements of human chronic kidney disease (CKD). Within weeks of surgery 5/6Nx rats spontaneously exhibit proximal tubular damage including the production of very large extracellular
Publikováno v:
Urolithiasis
Urine proteins are thought to control calcium oxalate stone formation, but over 1000 proteins have been reported in stone matrix obscuring their relative importance. Proteins critical to stone formation should be present at increased relative abundan
Publikováno v:
Urolithiasis
Calcium oxalate monohydrate (COM) crystals are the primary constituent of most kidney stones, but urine proteins in stone matrix are believed to be critical elements for stone formation from these crystals. Recent data have shown that hundreds of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce335f1b7e452a6eac357b97f9cdabec
https://europepmc.org/articles/PMC8316271/
https://europepmc.org/articles/PMC8316271/