Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Brian R, Edlin"'
Autor:
Benjamin Eckhardt, Pedro Mateu-Gelabert, Yesenia Aponte-Melendez, Chunki Fong, Shashi Kapadia, Melinda Smith, Brian R. Edlin, Kristen M. Marks
Publikováno v:
JAMA Intern Med
IMPORTANCE: To achieve hepatitis C elimination, treatment programs need to engage, treat, and cure people who inject drugs. OBJECTIVE: To compare a low-threshold, nonstigmatizing hepatitis C treatment program that was colocated at a syringe service p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef39ab1b371891ab62a12f69490042ef
https://pubmed.ncbi.nlm.nih.gov/35816336
https://pubmed.ncbi.nlm.nih.gov/35816336
Autor:
Sheila M Keating, Jennifer L Dodge, Philip J Norris, John Heitman, Stephen J Gange, Audrey L French, Marshall J Glesby, Brian R Edlin, Patricia S Latham, Maria C Villacres, Ruth M Greenblatt, Marion G Peters, Women’s Interagency HIV Study
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0181004 (2017)
Hepatitis C virus infection induces inflammation and while it is believed that HIV co-infection enhances this response, HIV control may reduce inflammation and liver fibrosis in resolved or viremic HCV infection. Measurement of systemic biomarkers in
Externí odkaz:
https://doaj.org/article/09bb6db1c27f444eab88b3eeb836c2e7
Autor:
Benjamin Eckhardt, Emily R Winkelstein, Marla A Shu, Michael R Carden, Courtney McKnight, Don C Des Jarlais, Marshall J Glesby, Kristen Marks, Brian R Edlin
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177341 (2017)
BACKGROUND:Hepatitis C virus (HCV) infection remains a significant problem in the United States, with people who inject drugs (PWID) disproportionately afflicted. Over the last decade rates of heroin use have more than doubled, with young persons (18
Externí odkaz:
https://doaj.org/article/269e80da5fce4aaf96c55870b43a5305
Autor:
Priya Duggal, James J. Goedert, Sharyne M. Donfield, Raymond T. Chung, Laurent Alric, Thomas R. O'Brien, Marion G. Peters, Gregory D. Kirk, Brian R. Edlin, Andrea L. Cox, Alex H. Kral, Valeria Piazzolla, Shruti H. Mehta, Eric O. Johnson, Michael P. Busch, Candelaria Vergara, Alessandra Mangia, Chloe L. Thio, Salim I. Khakoo, Genevieve L. Wojcik, Ana Valencia, Margaret A. Taub, Edward L. Murphy, Hugo R. Rosen, Arthur Y. Kim, Matthew E. Cramp, Georg M. Lauer, David L. Thomas, Graeme J.M. Alexander
Publikováno v:
J Infect Dis
The Journal of infectious diseases, vol 223, iss 12
The Journal of infectious diseases, vol 223, iss 12
Background Spontaneous clearance of acute hepatitis C virus (HCV) infection is more common in women than in men, independent of known risk factors. Methods To identify sex-specific genetic loci, we studied 4423 HCV-infected individuals (2903 male, 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df469e3a74d8f3c27575ce995c90ebf6
https://doi.org/10.1093/infdis/jiaa677
https://doi.org/10.1093/infdis/jiaa677
Autor:
Arthur Y. Kim, Matthew E. Cramp, David L. Thomas, Graeme J.M. Alexander, Sharyne M. Donfield, Georg M. Lauer, Valeria Piazzola, Raymond T. Chung, Candelaria Vergara, Priya Duggal, Salim I. Khakoo, Laurent Alric, Winston Timp, James J. Goedert, Marion G. Peters, Ana Valencia, Shruti H. Mehta, Andrea L. Cox, Chloe L. Thio, Eric O. Johnson, Michael P. Busch, Alessandra Mangia, Genevieve L. Wojcik, Thomas R. O'Brien, Gregory D. Kirk, Rachel Latanich, Alex H. Kral, Brian R. Edlin, Sarah J. Wheelan, Hugo R. Rosen, Margaret A. Taub, Edward L. Murphy
Publikováno v:
Genes and immunity
Genes and immunity, vol 21, iss 5
Genes and immunity, vol 21, iss 5
Clearance of acute infection with hepatitis C virus (HCV) is associated with the chr19q13.13 region containing the rs368234815 (TT/ΔG) polymorphism. We fine-mapped this region to detect possible causal variants that may contribute to HCV clearance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bc516e8c629b05f6e7f05b6ba298b8
http://europepmc.org/articles/PMC7657970
http://europepmc.org/articles/PMC7657970
Publikováno v:
J Infect Dis
BackgroundWe assessed prevalence of testing for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection among persons who inject drugs (PWID).MethodsUsing a nationwide health insurance database for claims paid during 2010–2017, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dccf5e41602725ca580f9751abc5cf
https://doi.org/10.1093/infdis/jiaa017
https://doi.org/10.1093/infdis/jiaa017
Autor:
Ana Valencia, Candelaria Vergara, Chloe L. Thio, Nicolas Vince, Venceslas Douillard, Alba Grifoni, Andrea L. Cox, Eric O. Johnson, Alex H. Kral, James J. Goedert, Alessandra Mangia, Valeria Piazzolla, Shruti H. Mehta, Gregory D. Kirk, Arthur Y. Kim, Georg M. Lauer, Raymond T. Chung, Jennifer C. Price, Salim I. Khakoo, Laurent Alric, Matthew E. Cramp, Sharyne M. Donfield, Brian R. Edlin, Michael P. Busch, Graeme Alexander, Hugo R. Rosen, Edward L. Murphy, Genevieve L. Wojcik, Mary Carrington, Pierre-Antoine Gourraud, Alessandro Sette, David L. Thomas, Priya Duggal
Publikováno v:
Am J Hum Genet
American journal of human genetics, vol 109, iss 2
American journal of human genetics, vol 109, iss 2
Spontaneous clearance of acute hepatitis C virus (HCV) infection is associated with single nucleotide polymorphisms (SNPs) on the MHC class II. We fine-mapped the MHC region in European (n = 1,600; 594 HCV clearance/1,006 HCV persistence) and African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50841c532ef830961912f68308d7e71f
https://europepmc.org/articles/PMC8874224/
https://europepmc.org/articles/PMC8874224/
Autor:
Krystle A Lang Kuhs, Mark H Kuniholm, Ruth M Pfeiffer, Sabrina Chen, Seema Desai, Brian R Edlin, Marion G Peters, Michael Plankey, Gerald B Sharp, Howard D Strickler, Maria C Villacres, Thomas C Quinn, Stephen J Gange, Ludmila Prokunina-Olsson, Ruth M Greenblatt, Thomas R O'Brien
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138827 (2015)
IFNL4-ΔG/TT (rs368234815) genotype is associated with hepatitis C virus clearance and may play a role in other infections. IFN-λ4 protein is generated only in individuals who carry the IFNL4-ΔG allele. The IFNL4 rs12979860-T allele, which is in st
Externí odkaz:
https://doaj.org/article/4c23707d1d064dcc951b98347b93808f
Publikováno v:
PLoS Medicine, Vol 3, Iss 10, p e452 (2006)
BackgroundStreet-based heroin injectors represent an especially vulnerable population group subject to negative health outcomes and social stigma. Effective clinical treatment and public health intervention for this population requires an understandi
Externí odkaz:
https://doaj.org/article/4c7f9de483204a39a72abccf6e6a6d4a
Autor:
Gregory D. Kirk, Raymond T. Chung, Priya Duggal, Alessandra Mangia, David L. Thomas, Margaret A. Taub, Brian R. Edlin, Rachel Latanich, Chloe L. Thio, Edward L. Murphy, Salim I. Khakoo, Alex H. Kral, Graeme J.M. Alexander, Thomas R. O'Brien, Hugo R. Rosen, Valeria Piazzolla, Sharyne M. Donfield, Shruti H. Mehta, James J. Goedert, Georg M. Lauer, Marion G. Peters, Arthur Y. Kim, Eric O. Johnson, Michael P. Busch, Andrea L. Cox, Matthew E. Cramp, Ana Valencia, Candelaria Vergara, Genevieve L. Wojcik, Laurent Alric
Publikováno v:
Gastroenterology
Gastroenterology, 2019, 156 (5), pp.1496-1507.e7. ⟨10.1053/j.gastro.2018.12.014⟩
Gastroenterology, WB Saunders, 2019, 156 (5), pp.1496-1507.e7. ⟨10.1053/j.gastro.2018.12.014⟩
Gastroenterology, vol 156, iss 5
Gastroenterology, 2019, 156 (5), pp.1496-1507.e7. ⟨10.1053/j.gastro.2018.12.014⟩
Gastroenterology, WB Saunders, 2019, 156 (5), pp.1496-1507.e7. ⟨10.1053/j.gastro.2018.12.014⟩
Gastroenterology, vol 156, iss 5
Background & aimsSpontaneous clearance of hepatitis C virus (HCV) occurs in approximately 30% of infected persons and less often in populations of African ancestry. Variants in major histocompatibility complex (MHC) and in interferon lambda genes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a6c322fdf1d8844a00a2ac2fd3f378
https://ut3-toulouseinp.hal.science/hal-03467677
https://ut3-toulouseinp.hal.science/hal-03467677