Organization of cellular receptors into a nanoscale junction during HIV-1 adhesion.

Autor: Terrence M Dobrowsky, Brian R Daniels, Robert F Siliciano, Sean X Sun, Denis Wirtz

Publikováno v: PLoS Computational Biology, Vol 6, Iss 7, p e1000855 (2010)

The fusion of the human immunodeficiency virus type 1 (HIV-1) with its host cell is the target for new antiretroviral therapies. Viral particles interact with the flexible plasma membrane via viral surface protein gp120 which binds its primary cellul

Externí odkaz: https://doaj.org/article/bf5510f8f1614efcbee09954fed30e25

Multi-ethnic genome-wide association study for atrial fibrillation

Autor: Marcus E. Kleber, Raji P. Grewal, Yingchang Lu, Sanghamitra Mohanty, Harry J.G.M. Crijns, Han Sun, Ilkka Seppälä, Jonathan D. Smith, Albert Hofman, Yii-Der Ida Chen, Diane Fatkin, Patrik K. E. Magnusson, Pil Sung Yang, Jari Laurikka, Saman Nazarian, Peter W. Macfarlane, Natalia S. Rost, Sekar Kathiresan, Heribert Schunkert, Sandosh Padmanabhan, Tõnu Esko, Bruno H. Stricker, Rebecca Gutmann, Alfredo José Mansur, Jonathan Rosand, Jesper Hastrup Svendsen, Alvaro Alonso, J. Gustav Smith, Benjamin Neumann, John Barnard, Christopher D. Anderson, Joanna Pera, Samir Saba, Lynne J. Hocking, Siew-Kee Low, Daniel I. Chasman, Patrick T. Ellinor, Nancy L. Pedersen, Stephan B. Felix, Vilmundur Gudnason, Kjell Nikus, Kahraman Tanriverdi, David J. Porteous, Samuel C. Dudley, Clive R. Pullinger, Tamara B. Harris, Barry London, Lorenz Risch, Ruth J. F. Loos, Rainer Malik, Isabelle C. Van Gelder, John F. Carlquist, Lena Refsgaard, Carolina Roselli, Albert Y. Sun, Man Li, Lenore J. Launer, Anders Hamsten, Svati H. Shah, Lin Y. Chen, Martina Müller-Nurasyid, Michiel Rienstra, Kent D. Taylor, Katharina Schramm, Jennifer A. Brody, Honghuang Lin, Eric Boerwinkle, Rozenn N. Lemaitre, Olle Melander, Hugh Calkins, Elsayed Z. Soliman, Moritz F. Sinner, Heather L. Bloom, Nicholas L. Smith, Nada Esa, John W. Cole, Maartje N. Niemeijer, David R. Van Wagoner, Anubha Mahajan, Roopinder K. Sandhu, Henry J. Lin, Jordi Jimenez-Conde, Ian Ford, Eue Keun Choi, Stacey Knight, Scott M. Damrauer, Markku Eskola, Claudia Schurman, Stuart A. Scott, Sara L. Pulit, Raymond Noordam, Mika Kähönen, Jay A. Montgomery, Agnieszka Slowik, Esra Gucuk Ipek, Joylene E. Siland, Lingyao Zeng, Andrew P. Morris, Oscar H. Franco, Bas L.J.H. Kietselaer, Adnan Kastrati, Dan E. Arking, José Eduardo Krieger, J. Wouter Jukema, Stefan Gustafsson, Nathan R. Tucker, Zachary T. Yoneda, Daniel Woo, Winfried März, Lauren Margolin, Uwe Völker, Stefan Kääb, Marju Orho-Melander, Lars Lind, Yoichiro Kamatani, Maris Teder-Laving, Paul M. Ridker, Bradford B. Worrall, Jaemin Shim, Bob Weijs, Ingrid E. Christophersen, Kenneth B. Margulies, James P. Cook, Graciela Delgado, Andrea Natale, Stefan Weiss, Gustav Ahlberg, Jie Huang, Guillaume Paré, M. Benjamin Shoemaker, Marcus Dörr, Arnljot Tveit, Elton A. M. P. Dudink, Thomas P. Cappola, Bruce M. Psaty, Alaa Shalaby, Gregory M. Marcus, Sébastien Thériault, Niek Verweij, Traci M. Bartz, Thorsten Kessler, Michael Morley, Xiuqing Guo, Alexandre C. Pereira, Efthymia Vlachopoulou, Albert V. Smith, Andrea R. V. R. Horimoto, David Conen, Erik Ingelsson, Jie Yao, Raul Weiss, David D. McManus, Michiaki Kubo, Lu-Chen Weng, Michael A. Rosenberg, Nona Sotoodehnia, Jennifer E. Huffman, Hui Nam Pak, Dan M. Roden, Peter Weeke, Joshua C. Bis, Archie Campbell, Marta Ribasés, Renee Johnson, Renate B. Schnabel, Christian M. Shaffer, Krishna G. Aragam, Seung Hoan Choi, André G. Uitterlinden, Morten S. Olesen, Toshihiro Tanaka, Daniel J. Rader, Mina K. Chung, Stella Trompet, Steven A. Lubitz, Martin Dichgans, Peter Almgren, Christine M. Albert, Blair H. Smith, Petra Katschnig-Winter, Joshua C. Denny, Christopher Newton-Cheh, Paulus Kirchhof, Namrata Gupta, Emelia J. Benjamin, Stefanie Aeschbacher, Marja-Liisa Lokki, Jorge A. Wong, Quinn S. Wells, Jussi Hernesniemi, Cecilia M. Lindgren, Mark Chaffin, Kaoru Ito, Jerome I. Rotter, Michael J. Cutler, Kerri L. Wiggins, Maryam Kavousi, Nathan A. Bihlmeyer, Bastiaan Geelhoed, Susan R. Heckbert, Caroline Hayward, Alexander Teumer, Paul L. Huang, Terho Lehtimäki, Juha Sinisalo, John P. Kane, Kirsten Leineweber, Tanja Zeller, Hong Euy Lim, Kathryn L. Lunetta, Brian R. Daniels, Heidi Oellers, Biqi Wang, Pim van der Harst, Peter M. Nilsson, Dawood Darbar, Erwin B. Bottinger, Leo-Pekka Lyytikäinen

Publikováno v: Nature Genetics, 50(9), 1225-+. Nature Publishing Group
Nature Genetics, 50(9), 1225-1233. Nature Publishing Group
Roselli, C, Chaffin, M, Weng, L-C, Aeschbacher, S, Ahlberg, G & Campbell, A 2018, ' Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation ', Nature Genetics, vol. 50, pp. 1225–1233 . https://doi.org/10.1038/s41588-018-0133-9
Nature Genetics
Nature Genetics, 50(9), 1225
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature genetics 50(9), 1225-1233 (2018). doi:10.1038/s41588-018-0133-9
Nat. Genet. 50, 1225–1233 (2018)

Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (GWAS) for AF to date, consisting of more than half a million i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf529668217fc475bd2fc1a391160e85
https://pure.eur.nl/en/publications/c85488bf-d180-41eb-aa8f-673f87bd2134

A Test of Current Models for the Mechanism of Milk-Lipid Droplet Secretion

Autor: Anil K. G. Kadegowda, Jerome Schaack, Hyunsu Shin, Ivonne Lisinski, Ian H. Mather, Jaekwang Jeong, Brian R. Daniels, F. B. Peter Wooding

Publikováno v: Traffic. 14:974-986

Milk lipid is secreted by a unique process, during which triacylglycerol droplets bud from mammary cells coated with an outer bilayer of apical membrane. In all current schemes, the integral protein butyrophilin 1A1 (BTN) is postulated to serve as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b962ca8d90be6099cdbbe4c6461c971
https://doi.org/10.1111/tra.12087

Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins

Autor: Robert F. Siliciano, James I. Mullins, Brian R. Daniels, Denis Wirtz, S. Alireza Rabi, Terrence M. Dobrowsky, Donald E. Mosier, Rebecca Nedellec

Publikováno v: Scientific Reports

In about half of patients infected with HIV-1 subtype B, viral populations shift from utilizing the transmembrane protein CCR5 to CXCR4, as well as or instead of CCR5, during late stage progression of the disease. How the relative adhesion efficiency

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9400440d3cd6aff61fb9ecb50c8b243
https://doi.org/10.1038/srep03014

Multiscale diffusion in the mitotic Drosophila melanogaster syncytial blastoderm

Autor: Terrence M. Dobrowsky, Brian R. Daniels, Jennifer Lippincott-Schwartz, Richa Rikhy, Malte Renz

Despite the fundamental importance of diffusion for embryonic morphogen gradient formation in the early Drosophila melanogaster embryo, there remains controversy regarding both the extent and the rate of diffusion of well-characterized morphogens. Fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d97e600cd1b3fb8e94ffe84a7b4b742
https://europepmc.org/articles/PMC3365200/