Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Brian Pepe-Mooney"'
Autor:
Wei-Chien Yuan, Brian Pepe-Mooney, Giorgio G. Galli, Michael T. Dill, Hai-Tsang Huang, Mingfeng Hao, Yumeng Wang, Han Liang, Raffaele A. Calogero, Fernando D. Camargo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Hippo-YAP pathway plays an important role in cancers; however the in vivo relevance of YAP/TAZ target genes is unclear. Here, the authors show that NUAK2 is a target of YAP and participates in a feedback loop to maximize YAP activity. Inhibition of N
Externí odkaz:
https://doaj.org/article/9fc9ce34002d427ca45e996eac694d2e
Autor:
Richard I. Gregory, Mehdi Pirouz, Daniel S. Pearson, Pavlos Missios, Amy S. Lee, George Q. Daley, Edroaldo Lummertz da Rocha, David T. Ting, Caroline Kubaczka, Kaloyan M. Tsanov, Joseph W. Franses, Daniel Dominguez, Brian Pepe-Mooney, Dorian Farache, John T. Powers, Deepak Kumar Jha, Julia Philipp, Maria M. Aleman
Publikováno v:
J Clin Invest
High expression of LIN28B is associated with aggressive malignancy and poor survival. Here, probing MYCN-amplified neuroblastoma as a model system, we showed that LIN28B expression was associated with enhanced cell migration in vitro and invasive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a147bf052b2a9df3483dfea7d1212b52
https://doi.org/10.1172/jci145142
https://doi.org/10.1172/jci145142