Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Brian Paul Lockhart"'
Autor:
Hélène Salaun, Charlotte Proudhon, Chantal Bourrier, Ellen Heitzer, Laura Xuereb, Michael R. Speicher, Nolwen Guigal-Stephan, Jean-Yves Pierga, Brian Paul Lockhart, Jelena Belic
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1481, p 1481 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1481, p 1481 (2020)
Volume 12
Issue 6
Background: Focal amplification of fibroblast growth factor receptor 1 (FGFR1) defines a subgroup of breast cancers with poor prognosis and high risk of recurrence. We sought to demonstrate the potential of circulating cell-free DNA (cfDNA) analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a9efe83b4ac36ea964b5756c762566
Autor:
Sabrina Le Bouter, Marianne Rodriguez, Nolwen Guigal-Stephan, Sophie Courtade-Gaïani, Laura Xuereb, Catherine de Montrion, Vincent Croixmarie, Thierry Umbdenstock, Claire Boursier-Neyret, Michel Lonchampt, Manuel Brun, Catherine Dacquet, Alain Ktorza, Brian-Paul Lockhart, Jean-Pierre Galizzi
Publikováno v:
PPAR Research, Vol 2010 (2010)
Rosiglitazone (RSG), developed for the treatment of type 2 diabetes mellitus, is known to have potent effects on carbohydrate and lipid metabolism leading to the improvement of insulin sensitivity in target tissues. To further assess the capacity of
Externí odkaz:
https://doaj.org/article/46df16f6182e4c53869defeac3035f9f
Autor:
Catherine Dacquet, Catherine de Montrion, Sabrina Le Bouter, Michel Lonchampt, Manuel Brun, Claire Boursier-Neyret, Nolwen Guigal-Stephan, Vincent Croixmarie, Brian-Paul Lockhart, Thierry Umbdenstock, Marianne Rodriguez, Sophie Courtade-Gaiani, Laura Xuereb, Jean-Pierre Galizzi, Alain Ktorza
Publikováno v:
PPAR Research, Vol 2010 (2010)
PPAR Research
PPAR Research
Rosiglitazone (RSG), developed for the treatment of type 2 diabetes mellitus, is known to have potent effects on carbohydrate and lipid metabolism leading to the improvement of insulin sensitivity in target tissues. To further assess the capacity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ea1b8a1b175f54305c4e09deb9c0ec
https://doi.org/10.1155/2010/679184
https://doi.org/10.1155/2010/679184
Publikováno v:
Brain Research. 670:313-316
In a previous study (Lockhart et al., Brain Res., 630 (1993) 32-40) we demonstrated a NMDA receptor-mediated neurotoxic effect for the anti-HIV drugs D-aspartate beta-hydroxamate and structurally related analogues in rat primary cortical neurons. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63698b12bf3c2b93211fb92e1a0306a7
https://doi.org/10.1016/0006-8993(94)01351-h
https://doi.org/10.1016/0006-8993(94)01351-h
Autor:
Brian Paul Lockhart, Martine Largeron, Maurice-Bernard Fleury, Leslie Schwendimann, Estelle Blattes, Pierre Gressens, P. Lestage
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2005, 48 (4), pp.1282-1286. ⟨10.1021/jm040874m⟩
Journal of Medicinal Chemistry, American Chemical Society, 2005, 48 (4), pp.1282-1286. ⟨10.1021/jm040874m⟩
International audience; 2-Alkylamino-substituted-1,4-benzoxazine derivatives, a new class of potential neuroprotective agents, were synthesized and examined for their intrinsic cytotoxicity and their capacity to inhibit oxidative stress-mediated neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e58754c16a4f7ee6e141626208e3949
https://pubmed.ncbi.nlm.nih.gov/15715499
https://pubmed.ncbi.nlm.nih.gov/15715499
Publikováno v:
Brain research. 675(1-2)
Substantiating evidence has raised the possibility that sigma ligands may have therapeutic potential as neuroprotective agents in brain ischemia. It has been suggested that the neuroprotective capacity of sigma ligands is related primarily to their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0293d90b5e33da703bbb642bdd14ab2
https://pubmed.ncbi.nlm.nih.gov/7796119
https://pubmed.ncbi.nlm.nih.gov/7796119
Publikováno v:
Journal of neuroscience research. 39(4)
The direct neurotoxic action of the beta-amyloid protein, the major constituent of senile plaques, may represent the underlying cause of neuronal degeneration observed in Alzheimer's disease. The apoptotic-mediated neuronal death induced by beta-amyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af657034b181ea765963c6607cb602f
https://pubmed.ncbi.nlm.nih.gov/7533847
https://pubmed.ncbi.nlm.nih.gov/7533847
Publikováno v:
Brain research. 630(1-2)
The anti-tumor drug d -aspartate β-hydroxamate ( d -AβH), selectively destroys HIV-1 infected peripheral blood mononuclear cells, but produces anorexia and nausea during prolonged treatment of AIDS patients. Consequently, based on the structural si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb410e43c79b75cbee39c42e6dbcc5c0
https://pubmed.ncbi.nlm.nih.gov/8118699
https://pubmed.ncbi.nlm.nih.gov/8118699