Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Brian P. Timko"'
Autor:
Olurotimi A. Bolonduro, Zijing Chen, Corey P. Fucetola, Yan‐Ru Lai, Megan Cote, Rofiat O. Kajola, Akshita A. Rao, Haitao Liu, Emmanuel S. Tzanakakis, Brian P. Timko
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Bioelectronic medicine is emerging as a powerful approach for restoring lost endogenous functions and addressing life‐altering maladies such as cardiac disorders. Systems that incorporate both modulation of cellular function and recording
Externí odkaz:
https://doaj.org/article/020f370655614048a95eb2fa744a9cb1
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 12, Pp n/a-n/a (2021)
Retinal prostheses are a promising therapeutic intervention for patients afflicted by outer retinal degenerative diseases such as retinitis pigmentosa and age‐related macular degeneration. Although significant advances in the development of retinal
Externí odkaz:
https://doaj.org/article/23c8e63760b14dbd8bbdd9b54f703378
Publikováno v:
Proc Natl Acad Sci U S A
Bioelectronic scaffolds that support devices while promoting tissue integration could enable tissue hybrids with augmented electronic capabilities. Here, we demonstrate a photo–cross-linkable silk fibroin (PSF) derivative and investigate its struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204f7f16cb57314cb0692a37e9b4af90
https://doi.org/10.1073/pnas.2003696117
https://doi.org/10.1073/pnas.2003696117
Publikováno v:
Nano Research. 13:1253-1267
Effective strategies in cardiac tissue engineering require matrices that recapitulate the mechanical, topographic and electrical cues present in the native extracellular matrix. In this review, we discuss recent efforts in materials science and nanot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca8f3f81c7aae5b537722eed24d1074
https://doi.org/10.1007/s12274-020-2682-3
https://doi.org/10.1007/s12274-020-2682-3
Autor:
Ning Hu, Breanna M. Duffy, Akshita A. Rao, Zhaohui Huang, Lauren D. Black, Jie Ju, Olurotimi A. Bolonduro, Haitao Liu, Brian P. Timko
Publikováno v:
Nano Letters. 20:2585-2593
We demonstrated a bioelectronic heart-on-a-chip model for studying the effects of acute hypoxia on cardiac function. A microfluidic channel enabled rapid modulation of medium oxygenation, which mimicked the regimes induced by a temporary coronary occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a10af2200716eda1438d18c7d3e3eb2
https://doi.org/10.1021/acs.nanolett.0c00076
https://doi.org/10.1021/acs.nanolett.0c00076
Autor:
Olurotimi A. Bolonduro, Haitao Liu, Brian P. Timko, Vineeth Raghuram, Jie Ju, Holden R. Fried, Bilal Haider
Publikováno v:
Nano Research. 11:5372-5399
Solid-state nanomaterials exhibit complementary interactions with biological systems because of their biologically-relevant size scales and rationally tunable electrical, chemical and mechanical properties. In this review, we focus specifically on on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::953ddaf6243b1040030566bc6ee035e7
https://doi.org/10.1007/s12274-018-2189-3
https://doi.org/10.1007/s12274-018-2189-3
Autor:
Brian P. Timko, Thanh D. Nguyen
Publikováno v:
Tissue Engineering for Artificial Organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24dfb24bb55f1508fd9d348dc7a882ba
https://doi.org/10.1002/9783527689934.ch21
https://doi.org/10.1002/9783527689934.ch21
Autor:
Brian P. Timko, Changyou Zhan, Alina Y. Rwei, Bruce Wang, Weiping Wang, Daniel S. Kohane, Claudia M. Santamaria
An injectable local anesthetic producing repeatable on-demand nerve block would be desirable for pain management. Here we present a phototriggerable device to achieve repeatable and adjustable on-demand local anesthesia in superficial or deep tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e6b3c8bce79a8d5d90dfdf34c8d944
https://europepmc.org/articles/PMC5469101/
https://europepmc.org/articles/PMC5469101/
Autor:
Brian P. Timko, Daniel S. Kohane
Publikováno v:
Expert Opinion on Drug Delivery. 11:1681-1685
Remotely triggered drug delivery devices have recently been realized as injectable or implantable formulations that enable the patient or physician to control the timing and dose of drug release over an extended period of time. Such devices could inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98953f3d190fd512b6c8a9999fd7c15
https://doi.org/10.1517/17425247.2014.930435
https://doi.org/10.1517/17425247.2014.930435
Autor:
Obiajulu S. Okonkwo, Leyre Gomez, J. Brian McAlvin, Sahadev A. Shankarappa, Daniel S. Kohane, Angela Zhu, Jia Zhu, Cristina F. Stefanescu, Jesus Santamaria, Robert Langer, Manuel Arruebo, Brian P. Timko, Boaz Mizrahi
Publikováno v:
Proceedings of the National Academy of Sciences. 111:1349-1354
A reservoir that could be remotely triggered to release a drug would enable the patient or physician to achieve on-demand, reproducible, repeated, and tunable dosing. Such a device would allow precise adjustment of dosage to desired effect, with a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f33f1087d81c3730df4a09016aef595
https://doi.org/10.1073/pnas.1322651111
https://doi.org/10.1073/pnas.1322651111