Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Brian P. Schoenfeld"'
Autor:
Brian P. Schoenfeld, Richard J. Choi, Catherine H. Choi, Allison M. Terlizzi, Paul eHinchey, Maria eKollaros, Neal J. Ferrick, Eric H. Koenigsberg, David eFerreiro, David A. Leibelt, Steve J. Siegel, Aaron J. Bell, Thomas V. McDonald, Thomas A. Jongens, Sean M.J. McBride
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Metabotropic glutamate receptors (mGluRs) have well established roles in cognition andsocial behavior in mammals. Whether or not these roles have been conserved throughoutevolution from invertebrate species is less clear. Mammals have 8 mGluRs wherea
Externí odkaz:
https://doaj.org/article/f7af92bdab5a4245982f8825c98b9b61
Autor:
Francois V. Bolduc, Rachel E. Monyak, Catherine H. Choi, Xiangzhong Zheng, Thomas V. McDonald, Thomas A. Jongens, Sean M.J. McBride, Brian P. Schoenfeld, Paul Hinchey, Amita Sehgal, Danielle Emerson, Daniel B. Chambers, Steven Langer, Cory Rosenfelt
Publikováno v:
Molecular psychiatry
Fragile X syndrome (FXS) is an undertreated neurodevelopmental disorder characterized by low intelligence quotent and a wide range of other symptoms including disordered sleep and autism. Although FXS is the most prevalent inherited cause of intellec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb2ef0d6bf638fccdd7a90ce3ac12e1
https://doi.org/10.1038/mp.2016.51
https://doi.org/10.1038/mp.2016.51
Autor:
Paul Hinchey, David A. Liebelt, Natalia Louneva, Joseph Hinchey, Allison M. Terlizzi, Steven J. Siegel, Francois V. Bolduc, Danielle Emerson, Ali Sharma, Brian P. Schoenfeld, Maria Kollaros, R. Suzanne Zukin, Michael Gertner, Catherine H. Choi, Sean Campbell, Aaron J. Bell, Neal J. Ferrick, Cory Rosenfelt, Steven Langer, Richard J. Choi, Eric Koenigsberg, Daniel B. Chambers, Steven E. Arnold, Robert E. Featherstone, Sean M.J. McBride, David Ferreiro, Thomas V. McDonald, Steven Sust, Aatika Malik, Thomas A. Jongens
Publikováno v:
Frontiers in Behavioral Neuroscience
Fragile X is the most common monogenic disorder associated with intellectual disability (ID) and autism spectrum disorders (ASD). Additionally, many patients are afflicted with executive dysfunction, ADHD, seizure disorder and sleep disturbances. Fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf00f6be203960a473f293f93172249
https://doi.org/10.3389/fnbeh.2016.00136
https://doi.org/10.3389/fnbeh.2016.00136
Autor:
Paul Hinchey, Michael Gertner, Brian P. Schoenfeld, R. Suzanne Zukin, Thomas V. McDonald, Catherine H. Choi, Newton H. Woo, Mark F. Bear, Aaron J. Bell, Michael R. Tranfaglia, Thomas A. Jongens, Maria Kollaros, Sean M.J. McBride
Publikováno v:
PMC
Fragile X syndrome is the leading single gene cause of intellectual disabilities. Treatment of a Drosophila model of Fragile X syndrome with metabotropic glutamate receptor (mGluR) antagonists or lithium rescues social and cognitive impairments. A ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4561ddb2ac8fc695fc8057c33cb951
https://doi.org/10.1016/j.brainres.2010.11.032
https://doi.org/10.1016/j.brainres.2010.11.032
Autor:
Paromita Banerjee, Sean M.J. McBride, Jae H. Park, Paul Hinchey, Thomas C. Dockendorff, Maria Kollaros, Michael P. Bradley, Brian P. Schoenfeld, Catherine H. Choi, Aaron J. Bell
Publikováno v:
The Journal of Neuroscience. 30:6782-6792
The diversity of protein isoforms arising from alternative splicing is thought to modulate fine-tuning of synaptic plasticity. Fragile X mental retardation protein (FMRP), a neuronal RNA binding protein, exists in isoforms as a result of alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09db4dc8299b9eed262bbbe128f639d
https://doi.org/10.1523/jneurosci.6369-09.2010
https://doi.org/10.1523/jneurosci.6369-09.2010
Autor:
Nicholas E. Baker, Sean M.J. McBride, Brian P. Schoenfeld, Galyna Sidyelyeva, Aaron J. Bell, Lloyd D. Fricker, Christian Wegener
Publikováno v:
Cellular and Molecular Life Sciences. 67:2991-3004
Metallocarboxypeptidase D (CPD) functions in protein and peptide processing. The Drosophila CPD svr gene undergoes alternative splicing, producing forms containing 1-3 active or inactive CP domains. To investigate the function of the various CP domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca0aa99bf035b56a5d08e1b62f5ff82
https://doi.org/10.1007/s00018-010-0369-8
https://doi.org/10.1007/s00018-010-0369-8
Autor:
Catherine H. Choi, Steven E. Arnold, Michael Gertner, Newton H. Woo, Thomas V. McDonald, Aaron J. Bell, Steven J. Siegel, Paul Hinchey, David A. Liebelt, Thomas A. Jongens, Eliana D. Weisz, Francois V. Bolduc, Brian P. Schoenfeld, Joseph Hinchey, Allison M. Terlizzi, Maria Kollaros, Nicole L. Yohn, R. Suzanne Zukin, Eric Koenigsberg, Neal J. Ferrick, Sean M.J. McBride, Natalia Louneva, Richard J. Choi, Michael R. Tranfaglia, Daniel B. Chambers
Fragile X syndrome (FXS) is the leading cause of both intellectual disability and autism resulting from a single gene mutation. Previously, we characterized cognitive impairments and brain structural defects in aDrosophilamodel of FXS and demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91fc0f7403f93081fe985fac884bec3
https://europepmc.org/articles/PMC4287155/
https://europepmc.org/articles/PMC4287155/
Autor:
Mark E. Fortini, Eric Koenigsberg, Thomas A. Jongens, Sean M.J. McBride, Paul Hinchey, David A. Liebelt, Neal J. Ferrick, Stephanie Chiorean, Hanh T. Nguyen, Catherine H. Choi, Richard J. Choi, Brian P. Schoenfeld, Allison M. Terlizzi, Maria Kollaros, Ai Sumida, David Ferreiro, Thomas V. McDonald, Rebecca L. Rudominer, Kathleen K. Siwicki, Aaron J. Bell
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(28)
Alzheimer9s disease (AD) is the leading cause of cognitive loss and neurodegeneration in the developed world. Although its genetic and environmental causes are not generally known, familial forms of the disease (FAD) are attributable to mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d98310050b7beb5d5536e953616ef8
https://pubmed.ncbi.nlm.nih.gov/20631179
https://pubmed.ncbi.nlm.nih.gov/20631179
Autor:
Ai Sumida, Paul Hinchey, David A. Liebelt, Catherine H. Choi, Thomas A. Jongens, Eric Koenigsberg, Maria Kollaros, Aaron J. Bell, Neal J. Ferrick, Sean M.J. McBride, Hanh T. Nguyen, David Ferreiro, Thomas V. McDonald, Rebecca L. Rudominer, Yan Wang, Allison M. Terlizzi, Brian P. Schoenfeld
Publikováno v:
Biogerontology. 11(3)
Fragile X syndrome afflicts 1 in 2,500 individuals and is the leading heritable cause of mental retardation worldwide. The overriding clinical manifestation of this disease is mild to severe cognitive impairment. Age-dependent cognitive decline has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1d38f361f019ec15e5750602ef78e2
https://pubmed.ncbi.nlm.nih.gov/20039205
https://pubmed.ncbi.nlm.nih.gov/20039205
Autor:
Salvatore Oddo, Frank M. LaFerla, Maria Gulinello, Sean M.J. McBride, Brian P. Schoenfeld, Donald S. Faber, Michael Gertner, Catherine H. Choi, Guadalupe Mendoza
We present a 2-day water maze protocol that addresses some of potential confounds present in the water maze when using the aged subjects typical of studies of neurodegenerative disorders, such as Alzheimer’s disease. This protocol is based on an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97872f220f55a0f59fb8ec344e67e97e
https://europepmc.org/articles/PMC4303046/
https://europepmc.org/articles/PMC4303046/