Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Brian P. Helmke"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128799 (2015)
Despite the life-preserving function blood clotting serves in the body, inadequate or excessive blood clot stiffness has been associated with life-threatening diseases such as stroke, hemorrhage, and heart attack. The relationship between blood clot
Externí odkaz:
https://doaj.org/article/6f5b47cc24a84cbabc04e7db7ae692fa
Publikováno v:
Biomedical Engineering Education. 1:243-243
Publikováno v:
Molecular Biology of the Cell
A laser trap was used to measure the molecular-scale forces generated at the surface of living Toxoplasma gondii in order to test the dominant theory of how these parasites move and invade host cells. The direction and magnitude of the cortical force
Publikováno v:
Annu Conf Expo (Am Soc Eng Educ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f45b02295f4000afacbd27e155c5ed4
https://europepmc.org/articles/PMC8479758/
https://europepmc.org/articles/PMC8479758/
Publikováno v:
Biomedical Engineering Education
Autor:
Brian P. Helmke, Lawrence Huang
Publikováno v:
Cellular and Molecular Bioengineering. 8:160-177
Endothelial cell (EC) alignment to directional flow or stretch supports anti-inflammatory functions, but mechanisms controlling polarized structural adaptation in response to physical cues remain unclear. This study aimed to determine whether factors
Autor:
Anshu B. Mathur, David W. Chang, Sanjay Kumar, C. Forbes Dewey, Geert W. Schmid-Schönbein, Cheng Zhu, Yingxiao Wang, Genevieve N. Brown, Peter J. Butler, Henry Hess, Robert M. Clegg, Brian P. Helmke, Roland Kaunas, X. Edward Guo, Shu Chien, Christopher R. Jacobs, Helen H. Lu, Roman J. Skoracki, Van C. Mow, Ning Wang, Cheng Dong
Publikováno v:
Cellular and Molecular Bioengineering. 5:239-253
In January of 2011, the Biomedical Engineering Society (BMES) and the Society for Physical Regulation in Biology and Medicine (SPRBM) held its inaugural Cellular and Molecular Bioengineering (CMBE) conference. The CMBE conference assembled worldwide
Publikováno v:
Annals of Biomedical Engineering. 38:1728-1740
Several custom-built and commercially available devices are available to investigate cellular responses to substrate strain. However, analysis of structural dynamics by microscopy in living cells during stretch is not readily feasible. We describe a
Publikováno v:
physica status solidi (a). 206:1356-1360
Bovine aortic endothelial cells were grown on nanostructured substrates consisting of pillars with height 10 μm, pitch 6 μm, and tip diameter 0.15 μm. Cells cultured on a pillar-covered substrate were more successful than those cultured on flat si
Autor:
Brian P. Helmke, Xiefan Lin
Publikováno v:
Cellular and Molecular Bioengineering. 2:231-243
Cobblestone-shaped endothelial cells in confluent monolayers undergo triphasic mechanotaxis in response to steady unidirectional shear stress, but cells that are elongated and aligned on micropatterned substrates do not change their migration behavio