Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Brian P. Bennett"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMechanistic understanding of transient exposures that lead to adverse health outcomes will enhance our ability to recognize biological signatures of disease. Here, we measured the transcriptomic and epigenomic alterations due to exposure to
Externí odkaz:
https://doaj.org/article/51af5221d82a4dbfae9bc844350e6dd7
Autor:
Anna C. Salvador, M. Nazmul Huda, Danny Arends, Ahmed M. Elsaadi, C. Anthony Gacasan, Gudrun A. Brockmann, William Valdar, Brian J. Bennett, David W. Threadgill
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Background The gut microbiota is modulated by a combination of diet, host genetics, and sex effects. The magnitude of these effects and interactions among them is important to understanding inter-individual variability in gut microbiota. In
Externí odkaz:
https://doaj.org/article/b402e2ffdfaf458f8c7d6ff0c082a0a0
Autor:
Thanh T. Hoang, Yunsung Lee, Daniel L. McCartney, Elin T.G. Kersten, Christian M. Page, Paige M. Hulls, Mikyeong Lee, Rosie M. Walker, Charles E. Breeze, Brian D. Bennett, Adam B. Burkholder, James Ward, Anne Lise Brantsæter, Ida H. Caspersen, Alison A. Motsinger-Reif, Marie Richards, Julie D. White, Shanshan Zhao, Rebecca C. Richmond, Maria C. Magnus, Gerard H. Koppelman, Kathryn L. Evans, Riccardo E. Marioni, Siri E. Håberg, Stephanie J. London, Bastiaan Heijmans, Peter ’t Hoen, Joyce van Meurs, Rick Jansen, Lude Franke, Dorret Boomsma, René Pool, Jenny van Dongen, Jouke Hottenga, Marleen van Greevenbroek, Coen Stehouwer, Carla van der Kallen, Casper Schalkwijk, Cisca Wijmenga, Sasha Zhernakova, Ettje Tigchelaar, P. Eline Slagboom, Marian Beekman, Joris Deelen, Diana Van Heemst, Jan Veldink, Leonard van den Berg, Cornelia van Duijn, Bert Hofman, Aaron Isaacs, André Uitterlinden, P. Mila Jhamai, Michael Verbiest, H. Eka Suchiman, Marijn Verkerk, Ruud van der Breggen, Jeroen van Rooij, Nico Lakenberg, Hailiang Mei, Maarten van Iterson, Michiel van Galen, Jan Bot, Dasha Zhernakova, Peter van ‘t Hof, Patrick Deelen, Irene Nooren, Matthijs Moed, Martijn Vermaat, René Luijk, Marc Bonder, Freerk van Dijk, Wibowo Arindrarto, Szymon Kielbasa, Morris Swertz, Erik van Zwet
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104956- (2024)
Summary: Background: Smoking impacts DNA methylation, but data are lacking on smoking-related differential methylation by sex or dietary intake, recent smoking cessation (
Externí odkaz:
https://doaj.org/article/3985b627485b4ff999b2ec073dfaf4e4
Autor:
Hye-Youn Cho, Xuting Wang, Michelle R. Campbell, Vijayalakshmi Panduri, Silvina Coviello, Mauricio T. Caballero, Brian D. Bennett, Steven R. Kleeberger, Fernando P. Polack, Gaston Ofman, Douglas A. Bell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract Bronchopulmonary dysplasia (BPD) is a prevalent chronic lung disease of prematurity with limited treatment options. To uncover biomarkers of BPD risk, this study investigated epigenetic and transcriptomic signatures of prematurity at birth a
Externí odkaz:
https://doaj.org/article/8cb45c3ead1241fc8305deb96342b095
Autor:
Myungsuk Kim, M. Nazmul Huda, Levi W. Evans, Excel Que, Erik R. Gertz, Nobuyo Maeda-Smithies, Brian J. Bennett
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Atherogenesis is an insipidus but precipitating process leading to serious consequences of many cardiovascular diseases (CVD). Numerous genetic loci contributing to atherosclerosis have been identified in human genome-wide association studie
Externí odkaz:
https://doaj.org/article/632900ad99cb46ddb4f5b4ae4ee6f692
Autor:
Phillip Wulfridge, Adam Davidovich, Anna C Salvador, Gabrielle C Manno, Rakel Tryggvadottir, Adrian Idrizi, M Nazmul Huda, Brian J Bennett, L Garry Adams, Kasper D Hansen, David W Threadgill, Andrew P Feinberg
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010997 (2023)
Diet-related metabolic syndrome is the largest contributor to adverse health in the United States. However, the study of gene-environment interactions and their epigenomic and transcriptomic integration is complicated by the lack of environmental and
Externí odkaz:
https://doaj.org/article/604db79494c6422c98dfaaf4680a4193
Autor:
Yining E. Wang, Catherine P. Kirschke, Leslie R. Woodhouse, Ellen L. Bonnel, Charles B. Stephensen, Brian J. Bennett, John W. Newman, Nancy L. Keim, Liping Huang
Publikováno v:
BMC Nutrition, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Background The effect of genetic polymorphisms on fasting blood lipid levels have been widely studied but the effects of these within the context of a high-fat meal challenge remain less characterized. The current study aimed to investigate
Externí odkaz:
https://doaj.org/article/b8b7a4c4a8234204806db9d50854f054
Autor:
Armin Ahmadi, Gwenaelle Begue, Ana P. Valencia, Jennifer E. Norman, Benjamin Lidgard, Brian J. Bennett, Matthew P. Van Doren, David J. Marcinek, Sili Fan, David K. Prince, Jorge Gamboa, Jonathan Himmelfarb, Ian H. de Boer, Bryan R. Kestenbaum, Baback Roshanravan
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
Background Current studies suggest mitochondrial dysfunction is a major contributor to impaired physical performance and exercise intolerance in chronic kidney disease (CKD). We conducted a clinical trial of coenzyme Q10 (CoQ10) and nicotinamide ribo
Externí odkaz:
https://doaj.org/article/152b024fbe374d49809a5ace393cfb86
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Introduction CD44 is a candidate gene for obesity and diabetes development and may be a critical mediator of a systemic inflammation associated with obesity and diabetes. Methods We investigated the relationship of CD44 with obesity in CD44-
Externí odkaz:
https://doaj.org/article/1bda23e25ead4f5c810b06f4da128235
Autor:
Megan G. Bragg, Elizabeth L. Prado, Bess L. Caswell, Charles D. Arnold, Matthews George, Lisa M. Oakes, Aaron G. Beckner, Michaela C. DeBolt, Brian J. Bennett, Kenneth M. Maleta, Christine P. Stewart
Publikováno v:
Maternal and Child Nutrition, Vol 19, Iss 2, Pp n/a-n/a (2023)
Abstract Choline is an essential micronutrient that may influence growth and development; however, few studies have examined postnatal choline status and children's growth and development in low‐ and middle‐income countries. The aim of this obser
Externí odkaz:
https://doaj.org/article/2780eebcb6254fc5812e709e124520da