Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Brian P McSharry"'
Autor:
Megan Steain, Max O D G Baker, Chi L L Pham, Nirukshan Shanmugam, Yann Gambin, Emma Sierecki, Brian P McSharry, Selmir Avdic, Barry Slobedman, Margaret Sunde, Allison Abendroth
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008473 (2020)
Herpesviruses are known to encode a number of inhibitors of host cell death, including RIP Homotypic Interaction Motif (RHIM)-containing proteins. Varicella zoster virus (VZV) is a member of the alphaherpesvirus subfamily and is responsible for causi
Externí odkaz:
https://doaj.org/article/4e3a10f9cb814c6dadddf2e5f88a920c
Autor:
Ceri A Fielding, Rebecca Aicheler, Richard J Stanton, Eddie C Y Wang, Song Han, Sepehr Seirafian, James Davies, Brian P McSharry, Michael P Weekes, P Robin Antrobus, Virginie Prod'homme, Fabien P Blanchet, Daniel Sugrue, Simone Cuff, Dawn Roberts, Andrew J Davison, Paul J Lehner, Gavin W G Wilkinson, Peter Tomasec
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004058 (2014)
NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MI
Externí odkaz:
https://doaj.org/article/7136c5273c614b6592fe5fe8187ff405
Autor:
Carolyn Samer, Hamish E.G. McWilliam, Brian P. McSharry, Thilaga Velusamy, James G. Burchfield, Richard J. Stanton, David C. Tscharke, Jamie Rossjohn, Jose A. Villadangos, Allison Abendroth, Barry Slobedman
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108801- (2024)
Summary: The major histocompatibility complex (MHC), Class-I-related (MR1) molecule presents microbiome-synthesized metabolites to Mucosal-associated invariant T (MAIT) cells, present at sites of herpes simplex virus (HSV) infection. During HSV type
Externí odkaz:
https://doaj.org/article/6e9ab8496a94412f99c1c5df7b46f8e0
Autor:
Caroline L. Ashley, Brian P. McSharry, Hamish E. G. McWilliam, Richard J. Stanton, Ceri A. Fielding, Rommel A. Mathias, David P. Fairlie, James McCluskey, Jose A. Villadangos, Jamie Rossjohn, Allison Abendroth, Barry Slobedman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe antigen presentation molecule MHC class I related protein-1 (MR1) is best characterized by its ability to present bacterially derived metabolites of vitamin B2 biosynthesis to mucosal-associated invariant T-cells (MAIT cells).MethodsT
Externí odkaz:
https://doaj.org/article/53babfbfbc814e488fc54d15c6f86de6
Adenoviruses in Avian Hosts: Recent Discoveries Shed New Light on Adenovirus Diversity and Evolution
Publikováno v:
Viruses, Vol 14, Iss 8, p 1767 (2022)
While adenoviruses cause infections in a wide range of vertebrates, members of the genus Atadenovirus, Siadenovirus, and Aviadenovirus predominantly infect avian hosts. Several recent studies on avian adenoviruses have encouraged us to re-visit previ
Externí odkaz:
https://doaj.org/article/958dd4221dfe4b16ad57e11e8e3c0419
Autor:
Brian P. McSharry, Carolyn Samer, Hamish E.G. McWilliam, Caroline L. Ashley, Michael B. Yee, Megan Steain, Ligong Liu, David P. Fairlie, Paul R. Kinchington, James McCluskey, Allison Abendroth, Jose A. Villadangos, Jamie Rossjohn, Barry Slobedman
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2948-2962.e4 (2020)
Summary: The antigen-presenting molecule MR1 presents microbial metabolites related to vitamin B2 biosynthesis to mucosal-associated invariant T cells (MAIT cells). Although bacteria and fungi drive the MR1 biosynthesis pathway, viruses have not prev
Externí odkaz:
https://doaj.org/article/8166c32232ce4ae29169a6ca737613b4
Autor:
Chelsea Gerada, Tessa M. Campbell, Jarrod J. Kennedy, Brian P. McSharry, Megan Steain, Barry Slobedman, Allison Abendroth
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Varicella zoster virus (VZV) is the causative agent of chickenpox (varicella) and shingles (herpes zoster). VZV and other members of the herpesvirus family are distinguished by their ability to establish a latent infection, with the potential to reac
Externí odkaz:
https://doaj.org/article/9b33cae0306745489a3f2560cc491dd5
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The critical role of interferons (IFNs) in mediating the innate immune response to cytomegalovirus (CMV) infection is well established. However, in recent years the functional importance of the IFN-independent antiviral response has become clearer. I
Externí odkaz:
https://doaj.org/article/9cdfaa50edfa47b5b0c9057973555bd4
Autor:
Hann Low, Nigora Mukhamedova, Huanhuan L. Cui, Brian P. McSharry, Selmir Avdic, Anh Hoang, Michael Ditiatkovski, Yingying Liu, Ying Fu, Peter J. Meikle, Martin Blomberg, Konstantinos A. Polyzos, William E. Miller, Piotr Religa, Michael Bukrinsky, Cecilia Soderberg-Naucler, Barry Slobedman, Dmitri Sviridov
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 186-200 (2016)
Cytomegalovirus (HCMV) contains cholesterol, but how HCMV interacts with host cholesterol metabolism is unknown. We found that, in human fibroblasts, HCMV infection increased the efflux of cellular cholesterol, despite reducing the abundance of ABCA1
Externí odkaz:
https://doaj.org/article/3e8942e781bd49fe8b389bb8108a2d62
Autor:
Mary Horgan, John MacSharry, Aimee McGreal, Corinna Sadlier, Susan Lapthorne, Cormac Everard, Liam O'Mahony, Brian P. McSharry, Nonhlanhla Lunjani, Gerard Murphy, Colin Sherlock, Sinead Ahearn-Ford, Anna McKeogh, Aoife Barry, Liam J. Fanning, Sultan Mohamed al Lawati, Arthur Jackson, Eamonn Faller
Publikováno v:
Allergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4276e4516bb06cca43aee8d570039d95
https://doi.org/10.1111/all.14953
https://doi.org/10.1111/all.14953