Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Brian O. Bodemann"'
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Table S1 contains the summary of the TBK1 inhibitor (BX795 and Compound II) screen in NSCLC lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440ef534d9d62da992469227ad3d43d6
https://doi.org/10.1158/0008-5472.22415562.v1
https://doi.org/10.1158/0008-5472.22415562.v1
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Table S3 contains the correlation data for TBK1 inhibitor (BX795 and Compound II) toxicity vs. mRNA expression in NSCLC lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d136690783b6f4383b3a5fe3ce54ac0
https://doi.org/10.1158/0008-5472.22415556
https://doi.org/10.1158/0008-5472.22415556
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Figure S4 shows that modulation of mesenchymal status is sufficient to alter Ras-Mutant NSCLC sensitivity to TBK1 inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3288862e8349d7f46954fa5b3a3c6cf2
https://doi.org/10.1158/0008-5472.22415565.v1
https://doi.org/10.1158/0008-5472.22415565.v1
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Table S2 contains the data for the comparisons between TBK1 inhibitors (BX795 and Compound II) and published chemical breadth of efficacy screens in NSCLC lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d361410d09b18444b5b682b9ff575f2
https://doi.org/10.1158/0008-5472.22415559
https://doi.org/10.1158/0008-5472.22415559
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Emerging observations link dysregulation of TANK-binding kinase 1 (TBK1) to developmental disorders, inflammatory disease, and cancer. Biochemical mechanisms accounting for direct participation of TBK1 in host defense signaling have been well describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b2e6dc9caf3fb54201e52051208d80
https://doi.org/10.1158/0008-5472.c.6509322.v1
https://doi.org/10.1158/0008-5472.c.6509322.v1
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Figure S3 shows supporting data for the identification of a TBK1-dependent molecular subtype of NSCLC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02586eec5751f21eb64d7443a995c88b
https://doi.org/10.1158/0008-5472.22415568.v1
https://doi.org/10.1158/0008-5472.22415568.v1
Autor:
Michael A. White, Bruce A. Posner, Gurbani Makkar, Brian O. Bodemann, Aubhishek Zaman, Rachel M. Vaden, Elizabeth A. McMillan, Yi-Hung Ou, Jonathan M. Cooper
Figure S2 contains the TBK1 adaptor-focused screen assessing the relative requirement of TBK1 first- and second-degree interactors for amino acid activation of mTORC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2e90b6fab36b9500d518b0e08aff31
https://doi.org/10.1158/0008-5472.22415571
https://doi.org/10.1158/0008-5472.22415571
Autor:
Yi Hung Ou, Michael A. White, Elizabeth A. McMillan, Aubhishek Zaman, Bruce A. Posner, Rachel M. Vaden, Gurbani Makkar, Jonathan M. Cooper, Brian O. Bodemann
Publikováno v:
Cancer Research. 77:5077-5094
Emerging observations link dysregulation of TANK-binding kinase 1 (TBK1) to developmental disorders, inflammatory disease, and cancer. Biochemical mechanisms accounting for direct participation of TBK1 in host defense signaling have been well describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e997c7aacfc0eb36a752ed43d3ffdeb
https://doi.org/10.1158/0008-5472.can-17-0829
https://doi.org/10.1158/0008-5472.can-17-0829
Autor:
Michael J. Torres, Saurabh Mendiratta, Brian O. Bodemann, Michael A. White, Ugur Eskiocak, Rosalyn Ram
Publikováno v:
Molecular and Cellular Biology. 34:2350-2358
The RASSF1A gene is one of the most frequently inactivated genes in over 30 different types of cancers (H. Donninger, M. D. Vos, and G. J. Clark, J. Cell Sci. 120:3163-3172, 2007, http://dx.doi.org/10.1242/jcs.010389). Despite the prevalence of RASSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d523b58ade0ec485bb22e8859e0a47
https://doi.org/10.1128/mcb.01506-13
https://doi.org/10.1128/mcb.01506-13
Publikováno v:
Journal of Molecular and Cellular Cardiology. 59:128-138
Recent work has demonstrated that autophagy, a phylogenetically conserved, lysosome-mediated pathway of protein degradation, is a key participant in pathological cardiac remodeling. One common feature of cell growth and autophagy is membrane biogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355663338dea93cc8d8f4c264169f1b5
https://doi.org/10.1016/j.yjmcc.2013.02.015
https://doi.org/10.1016/j.yjmcc.2013.02.015