Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Brian O Barnstein"'
Autor:
Heather L. Caslin, Marcela T. Taruselli, Tamara Haque, Neha Pondicherry, Elizabeth A. Baldwin, Brian O. Barnstein, John J. Ryan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Cellular metabolism and energy sensing pathways are closely linked to inflammation, but there is little understanding of how these pathways affect mast cell function. Mast cells are major effectors of allergy and asthma, and can be activated by the a
Externí odkaz:
https://doaj.org/article/89b13b0cabb443c1bc42e1f2570ecac3
Autor:
Heather L. Caslin, Brian O. Barnstein, Charles E. Chalfant, Neha Pondicherry, Daniel Abebayehu, L. Alexis Hoeferlin, Patrick A Paez, Tamara T. Haque, Amina Abdul Qayum, Marcela T. Taruselli, John J. Ryan
Publikováno v:
J Immunol
Sepsis has a well-studied inflammatory phase, with a less-understood secondary immunosuppressive phase. Elevated blood lactate and slow lactate clearance are associated with mortality; however, regulatory roles are unknown. We hypothesized that lacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f6db542e2770805bd8a57b6fd1aa73
https://doi.org/10.4049/jimmunol.1801005
https://doi.org/10.4049/jimmunol.1801005
Autor:
Heather L. Caslin, Tamara T. Haque, Neha Pondicherry, Marcela T. Taruselli, Andrew J. Spence, Jordan M. Dailey, Kaitlyn Jackson, Amina Abdul Qayum, Sydney A. Kee, David B. Straus, Jason R. Burchett, John J. Ryan, Gregorio Gomez, Elizabeth Motunrayo Kolawole, Brian O. Barnstein, Daniel Abebayehu
Publikováno v:
Cell Immunol
Statins are HMG-CoA reductase inhibitors prescribed for lowering cholesterol. They can also inhibit inflammatory responses by suppressing isoprenylation of small G proteins. Consistent with this, we previously found that fluvastatin suppresses IgE-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308a25df94cee1b4124fe1827b0efc8e
https://pubmed.ncbi.nlm.nih.gov/34883342
https://pubmed.ncbi.nlm.nih.gov/34883342
Autor:
David B. Straus, Destiny Pryor, Tamara T. Haque, Sydney A. Kee, Jordan M. Dailey, Kaitlyn G. Jackson, Brian O. Barnstein, John J. Ryan
Publikováno v:
Cellular Immunology. 371:104470
Inflammatory responses are required to block pathogen infection but can also lead to hypersensitivity and chronic inflammation. Barrier tissues actively release IL-33, ATP, and other alarmins during cell stress, helping identify pathogenic stimuli. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c4c911f0ec14dbae10060655a6f0e3
https://doi.org/10.1016/j.cellimm.2021.104470
https://doi.org/10.1016/j.cellimm.2021.104470
Autor:
Brian O. Barnstein, Kasalina N. Kiwanuka, Fred D. Finkelman, Amina Abdul Qayum, John J. Ryan, Tamara T. Haque, Peter A. Nigrovic, Anuya Paranjape
Publikováno v:
Cellular immunology. 356
Mast cells, well established effectors in allergic disease, can be activated by numerous stimuli. We previously found that the Fyn-Stat5B pathway is critical for FceRI-stimulated mast cell function. Because IgG receptors employ similar signaling path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954217950d4f5fd74e617579c4b81dfa
https://pubmed.ncbi.nlm.nih.gov/32862025
https://pubmed.ncbi.nlm.nih.gov/32862025
Autor:
John J. Ryan, E. Motunrayo Kolawole, Heather L. Caslin, David B. Straus, Patrick A Paez, Rebecca K. Martin, Brian O. Barnstein, Siddarth Ajith, Jamie Josephine Avila McLeod, Marcela T. Taruselli, Lawrence B. Schwartz, David A. Gewirtz, Quang T. Le, Yoshihiro Fukuoka, Kasalina N. Kiwanuka, Tamara T. Haque, Jordan M. Dailey, Sydney A. Kee
Publikováno v:
J Pharmacol Exp Ther
Statin drugs are widely employed in the clinic to reduce serum cholesterol. Because of their hydroxymethylglutaryl coenzyme A reductase antagonism, statins also reduce isoprenyl lipids necessary for the membrane anchorage and signaling of small G-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419e1893c555a9fbd145216ab640f613
https://pubmed.ncbi.nlm.nih.gov/32434944
https://pubmed.ncbi.nlm.nih.gov/32434944
Autor:
Marcela T. Taruselli, John J. Ryan, Jamie Josephine Avila McLeod, Andrew J. Spence, Amina Abdul Qayum, Victor S. Ndaw, Bianca Baker, Heather L. Caslin, Alena P. Chumanevich, Brian O. Barnstein, Elizabeth Motunrayo Kolawole, Daniel Abebayehu, Anuya Paranjape, Carole A. Oskeritzian, Scott A. Sell
Publikováno v:
The Journal of Immunology. 197:2909-2917
Lactic acid (LA) is present in tumors, asthma, and wound healing, environments with elevated IL-33 and mast cell infiltration. Although IL-33 is a potent mast cell activator, how LA affects IL-33–mediated mast cell function is unknown. To investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17b2eb884379d36d090d6c06dfdf2c0
https://doi.org/10.4049/jimmunol.1600651
https://doi.org/10.4049/jimmunol.1600651
Autor:
Kevin O. Rivera, Daniel H. Conrad, Nicholas Pullen, Jamie Josephine Avila McLeod, Brian O. Barnstein, John J. Ryan, Elizabeth Motunrayo Kolawole, Josephine Fernando, Travis Faber, Marcela T. Taruselli, Kathryn L. Williams
Publikováno v:
Cellular Immunology. 290:80-88
A Disintegrin And Metalloproteinase (ADAM)-10 plays critical roles in neuronal migration and distribution. Recently, ADAM10 deletion was shown to disrupt myelopoiesis. We found that inducible deletion of ADAM10 using Mx1-driven Cre recombinase for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1605913c271f8808a8ba627eb25d2b35
https://doi.org/10.1016/j.cellimm.2014.05.005
https://doi.org/10.1016/j.cellimm.2014.05.005
The HMGCR Inhibitor Fluvastatin Induces Apoptosis and Autophagy in Primary and Neoplastic Mast Cells
Publikováno v:
The Journal of Immunology. 202:54.12-54.12
Mast cell hyperplasia is noted in many inflammatory and allergic diseases. Mast cells can also generate a subtype of acute myelogenous leukemia. Understanding and treating mast cell hyperplasia and leukemia could be beneficial to both inflammatory an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acd8dac67cbbb23adc70fb0438c63444
https://doi.org/10.4049/jimmunol.202.supp.54.12
https://doi.org/10.4049/jimmunol.202.supp.54.12
Autor:
Brian O. Barnstein, John J. Ryan, L. Franzel, Travis Faber, Massimo F. Bertino, Stephen Mutisya
Publikováno v:
Applied Surface Science. 264:27-30
Au nanoparticles were generated by laser ablation in PBS buffer and conjugated to immunoglobulin E (IgE) during ablation ( in situ ) and after ablation ( ex situ ). Exposure for 5 min to 532 nm pulses with a duration of 150 ps, an energy of 8 mJ and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21db43704c385911ab9ec201eb0027a6
https://doi.org/10.1016/j.apsusc.2012.09.064
https://doi.org/10.1016/j.apsusc.2012.09.064